Enhancing gene editing specificity by attenuating DNA cleavage kinetics.

Autor: Miller JC; Sangamo Therapeutics, Inc., Richmond, CA, USA., Patil DP; Sangamo Therapeutics, Inc., Richmond, CA, USA., Xia DF; Sangamo Therapeutics, Inc., Richmond, CA, USA., Paine CB; Sangamo Therapeutics, Inc., Richmond, CA, USA., Fauser F; Sangamo Therapeutics, Inc., Richmond, CA, USA., Richards HW; Sangamo Therapeutics, Inc., Richmond, CA, USA., Shivak DA; Sangamo Therapeutics, Inc., Richmond, CA, USA., Bendaña YR; Sangamo Therapeutics, Inc., Richmond, CA, USA., Hinkley SJ; Sangamo Therapeutics, Inc., Richmond, CA, USA., Scarlott NA; Sangamo Therapeutics, Inc., Richmond, CA, USA., Lam SC; Sangamo Therapeutics, Inc., Richmond, CA, USA., Reik A; Sangamo Therapeutics, Inc., Richmond, CA, USA., Zhou Y; Sangamo Therapeutics, Inc., Richmond, CA, USA., Paschon DE; Sangamo Therapeutics, Inc., Richmond, CA, USA., Li P; Sangamo Therapeutics, Inc., Richmond, CA, USA., Wangzor T; Sangamo Therapeutics, Inc., Richmond, CA, USA., Lee G; Sangamo Therapeutics, Inc., Richmond, CA, USA., Zhang L; Sangamo Therapeutics, Inc., Richmond, CA, USA., Rebar EJ; Sangamo Therapeutics, Inc., Richmond, CA, USA. erebar@sangamo.com.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2019 Aug; Vol. 37 (8), pp. 945-952. Date of Electronic Publication: 2019 Jul 29.