Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paige Winokur"'
Autor:
Samantha V. Shetty, Michael R. Mazzucco, Paige Winokur, Sylvia V. Haigh, Kareem Rashid Rumah, Vincent A. Fischetti, Timothy Vartanian, Jennifer R. Linden
Publikováno v:
Toxins, Vol 15, Iss 7, p 423 (2023)
Clostridium perfringens epsilon toxin (ETX) is the third most lethal bacterial toxin and has been suggested to be an environmental trigger of multiple sclerosis, an immune-mediated disease of the human central nervous system. However, ETX cytotoxicit
Externí odkaz:
https://doaj.org/article/888a14a889c84693a63a1d03514c6b36
Autor:
Linden, Samantha V. Shetty, Michael R. Mazzucco, Paige Winokur, Sylvia V. Haigh, Kareem Rashid Rumah, Vincent A. Fischetti, Timothy Vartanian, Jennifer R.
Publikováno v:
Toxins; Volume 15; Issue 7; Pages: 423
Clostridium perfringens epsilon toxin (ETX) is the third most lethal bacterial toxin and has been suggested to be an environmental trigger of multiple sclerosis, an immune-mediated disease of the human central nervous system. However, ETX cytotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::43b626db3e67ba5ff49da4019fabc2fc
Autor:
Mika Komori, Anil A. Panackal, Yen Chih Lin, Paige Winokur, Tianxia Wu, Andrew Blake, Danish Ghazali, Simone C. Wuest, Muktha S Natrajan, Bibiana Bielekova, Elena Romm, Peter Kosa, Peter R. Williamson, Mark C. Greenwood
Publikováno v:
Annals of Neurology. 78:3-20
Objective The management of complex patients with neuroimmunological diseases is hindered by an inability to reliably measure intrathecal inflammation. Currently implemented laboratory tests developed >40 years ago either are not dynamic or fail to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afcc9bc4b16168f842aacfde9fbe8d44
https://doi.org/10.1002/ana.24408
https://doi.org/10.1002/ana.24408
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Novel treatments such as natalizumab and fingolimod achieve their therapeutic efficacy in multiple sclerosis (MS) by blocking access of subsets of immune cells into the central nervous system, thus creating nonphysiological intrathecal immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afd1361d48609fad02a101878e4c8a5
https://doi.org/10.1002/acn3.181
https://doi.org/10.1002/acn3.181
Autor:
Graham D. Brown, Craig S. Moore, Jean Pyo Lee, Ernesto R. Bongarzone, Stephen J. Crocker, Kumiko Ijichi, Evan Y. Snyder, Paige Winokur, Roberto Pagarigan
Publikováno v:
Glia. 61:765-777
Globoid cell leukodystrophy (GLD) or Krabbe disease, is a fatal demyelinating disease attributed to mutations in the galactocerebrosidase (GALC) gene. Loss of function mutations in GALC result in accumulation of the glycolipid intermediate, galactosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd9dc15b0ede824b81e2c3d019558d9
https://doi.org/10.1002/glia.22471
https://doi.org/10.1002/glia.22471
Autor:
Jody Manischewitz, Hana Golding, Yen Chih Lin, Elena Romm, Tianxia Wu, Lisa R. King, Paige Winokur, Bibiana Bielekova, Andrew Blake
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
Objective: The purpose of this study was to assess the potential immunosuppressive role of daclizumab, a humanized monoclonal antibody against the α chain of the interleukin 2 receptor, in vivo, by comparing immune responses to the 2013 seasonal inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ff17d5fd195280a6741eccd178c752
https://pubmed.ncbi.nlm.nih.gov/26848487
https://pubmed.ncbi.nlm.nih.gov/26848487
Autor:
Paige Winokur, Ernesto R. Bongarzone, Stephen J. Crocker, Kumiko I. Claycomb, Alexandra M. Nicaise, Kasey M. Johnson, Elisa Barbarese, Anthony Giampetruzzi, Evan Y. Snyder, Anthony V. Sacino
Globoid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galactosylsphingosine (psychosine). We recently reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47a97d2adbf18c64981703a54aa84e6
https://europepmc.org/articles/PMC4169335/
https://europepmc.org/articles/PMC4169335/
Autor:
Mika, Komori, Andrew, Blake, Mark, Greenwood, Yen Chih, Lin, Peter, Kosa, Danish, Ghazali, Paige, Winokur, Muktha, Natrajan, Simone C, Wuest, Elena, Romm, Anil A, Panackal, Peter R, Williamson, Tianxia, Wu, Bibiana, Bielekova
Publikováno v:
Annals of neurology. 78(1)
The management of complex patients with neuroimmunological diseases is hindered by an inability to reliably measure intrathecal inflammation. Currently implemented laboratory tests developed40 years ago either are not dynamic or fail to capture low l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d72f308897eb04b8038a8c222652f11
https://pubmed.ncbi.nlm.nih.gov/25808056
https://pubmed.ncbi.nlm.nih.gov/25808056
Publikováno v:
Brain Sciences
Brain Sciences, Vol 3, Iss 3, Pp 1109-1127 (2013)
Brain Sciences, Vol 3, Iss 3, Pp 1109-1127 (2013)
Astrocytes regulate fundamentally important functions to maintain central nervous system (CNS) homeostasis. Altered astrocytic function is now recognized as a primary contributing factor to an increasing number of neurological diseases. In this revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6fde4cfcb6a80686a6be433ca40e0b
https://pubmed.ncbi.nlm.nih.gov/24961523
https://pubmed.ncbi.nlm.nih.gov/24961523