Výsledky vyhledávání - "Paige S. Hansen"

CD47 Blockade Leads to Chemokine-Dependent Monocyte Infiltration and Loss of B Cells from the Splenic Marginal Zone

Autor: Ying Ying Yiu, Paige S. Hansen, Laughing Bear Torrez Dulgeroff, Grace Blacker, Lara Myers, Sarah Galloway, Eric Gars, Olivia Colace, Paul Mansfield, Kim J. Hasenkrug, Irving L. Weissman, Michal Caspi Tal

Publikováno v: J Immunol

CD47 is an important innate immune checkpoint through its interaction with its inhibitory receptor on macrophages, signal-regulatory protein α (SIRPα). Therapeutic blockade of CD47–SIRPα interactions is a promising immuno-oncology treatment that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506185d192a6ad6c7bf843a33ec3c6b3
https://europepmc.org/articles/PMC9012117/

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Increased macrophage phagocytic activity with TLR9 agonist conjugation of an anti- Borrelia burgdorferi monoclonal antibody

Autor: Shaghayegh, Jahanbani, Paige S, Hansen, Lisa K, Blum, Effie E, Bastounis, Nitya S, Ramadoss, Mallesh, Pandrala, Jessica Marie, Kirschmann, Grace Sisemore, Blacker, Zelda Z, Love, Irving L, Weissman, Fahimeh, Nemati, Michal Caspi, Tal, William H, Robinson

Publikováno v: Clinical Immunology. 246:109180

Borrelia burgdorferi (Bb) infection causes Lyme disease, for which there is need for more effective therapies. Here, we sequenced the antibody repertoire of plasmablasts in Bb-infected humans. We expressed recombinant monoclonal antibodies (mAbs) rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0204a0507ece940bc600dd481b31796c
https://doi.org/10.1016/j.clim.2022.109180

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