Zobrazeno 1 - 2
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pro vyhledávání: '"Paige Kerr"'
Role of channel activation in cognitive enhancement mediated by α7 nicotinic acetylcholine receptors
Autor:
William H. Bunnelle, Tino Dyhring, Jens Halvard Grønlien, David J. Anderson, Peter Curzon, John Malysz, Gunnar M. Olsen, Kirsten Thorin-Hagene, Clark A. Briggs, Paige Kerr, Hilde Ween, Murali Gopalakrishnan, Daniel B. Timmermann, Dan Peters
Publikováno v:
British Journal of Pharmacology. 158:1486-1494
Background and purpose: Several agonists of the α7 nicotinic acetylcholine receptor (nAChR) have been developed for treatment of cognitive deficits. However, agonist efficacy in vivo is difficult to reconcile with rapid α7 nAChR desensitization in
Autor:
Clark A, Briggs, Jens Halvard, Grønlien, Peter, Curzon, Daniel B, Timmermann, Hilde, Ween, Kirsten, Thorin-Hagene, Paige, Kerr, David J, Anderson, John, Malysz, Tino, Dyhring, Gunnar M, Olsen, Dan, Peters, William H, Bunnelle, Murali, Gopalakrishnan
Publikováno v:
British journal of pharmacology. 158(6)
Several agonists of the alpha7 nicotinic acetylcholine receptor (nAChR) have been developed for treatment of cognitive deficits. However, agonist efficacy in vivo is difficult to reconcile with rapid alpha7 nAChR desensitization in vitro; and further