Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Paige K. Arnold"'
Autor:
Srivarsha Rajshekar, Jun Yao, Paige K Arnold, Sara G Payne, Yinwen Zhang, Teresa V Bowman, Robert J Schmitz, John R Edwards, Mary Goll
Publikováno v:
eLife, Vol 7 (2018)
Pericentromeric satellite repeats are enriched in 5-methylcytosine (5mC). Loss of 5mC at these sequences is common in cancer and is a hallmark of Immunodeficiency, Centromere and Facial abnormalities (ICF) syndrome. While the general importance of 5m
Externí odkaz:
https://doaj.org/article/17b088700f0a408984fdd17bfa82fe16
Autor:
Paige K. Arnold, Lydia W.S. Finley
Publikováno v:
The Journal of biological chemistry.
The tricarboxylic acid (TCA) cycle, otherwise known as the Krebs cycle, is a central metabolic pathway that performs the essential function of oxidizing nutrients to support cellular bioenergetics. More recently, it has become evident that TCA cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa428722fe3e0b93b00fd4575395a60
https://pubmed.ncbi.nlm.nih.gov/36581208
https://pubmed.ncbi.nlm.nih.gov/36581208
Autor:
Lydia W.S. Finley, Craig B. Thompson, Santosha Vardhana, Bryce W. Carey, Paige K. Arnold, Carlos Carmona-Fontaine, Yanyang Chen, Bess P. Rosen, Danwei Huangfu
Publikováno v:
Nature metabolism
Most rapidly proliferating mammalian cells rely on the oxidation of exogenous glutamine to support cell proliferation. We previously found that culture of mouse embryonic stem cells (ESCs) in the presence of inhibitors against MEK and GSK3β to maint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a5dfddce9dfa356244d8bc2fdbfad
https://doi.org/10.1038/s42255-019-0082-3
https://doi.org/10.1038/s42255-019-0082-3
Autor:
Paige K. Arnold, Benjamin T. Jackson, Katrina I. Paras, Julia S. Brunner, Madeleine L. Hart, Oliver J. Newsom, Sydney P. Alibeckoff, Jennifer Endress, Esther Drill, Lucas B. Sullivan, Lydia W. S. Finley
Publikováno v:
Nature
The tricarboxylic acid (TCA) cycle is a central hub of cellular metabolism, oxidizing nutrients to generate reducing equivalents for energy production and critical metabolites for biosynthetic reactions. Despite the importance of TCA cycle products f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8201ffa8f357cc1b8ae54b235279cbfc
https://pubmed.ncbi.nlm.nih.gov/35764605
https://pubmed.ncbi.nlm.nih.gov/35764605
Autor:
Lydia W.S. Finley, Esther Drill, Paige K. Arnold, Benjamin T. Jackson, Lucas B. Sullivan, Sydney P. Alibeckoff
Publikováno v:
Cancer Research. 80:PO-021
Cells utilize diverse metabolic strategies to support cell type-specific bioenergetic requirements. The enzymes that mediate cellular metabolic processes have been well studied. However, how cells coordinate these factors into metabolic networks rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17041ddf216d3a13577ca38c2c0d835
https://doi.org/10.1158/1538-7445.epimetab20-po-021
https://doi.org/10.1158/1538-7445.epimetab20-po-021
Autor:
Jun Yao, Paige K. Arnold, Sara G. Payne, John R. Edwards, Yinwen Zhang, Robert J. Schmitz, Mary G. Goll, Srivarsha Rajshekar, Teresa V. Bowman
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Pericentromeric satellite repeats are enriched in 5-methylcytosine (5mC). Loss of 5mC at these sequences is common in cancer and is a hallmark of Immunodeficiency, Centromere and Facial abnormalities (ICF) syndrome. While the general importance of 5m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aca3cfcfa5a501c030f20ca2741968e
https://doi.org/10.7554/elife.39658
https://doi.org/10.7554/elife.39658
Autor:
Mary G. Goll, Robert J. Schmitz, John R. Edwards, Sara G. Payne, Jun Yao, Paige K. Arnold, Srivarsha Rajshekar, Teresa V. Bowman, Yinwen Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070faf44f120a723836fc23b5686cc5a
https://doi.org/10.7554/elife.39658.033
https://doi.org/10.7554/elife.39658.033
Autor:
Pierre P. Massion, Julien Sage, Paige K. Arnold, Afshin Dowlati, Charles M. Rudin, John T. Poirier, John Campbell, Patrice Desmeules, Natasha Rekhtman, Benjamin H. Lok, Eric E. Gardner, Scott Ribich, Thuyen Nguyen, Andy Ni, Valentina E. Schneeberger, Elisa de Stanchina, Inna Khodos, Linde A. Miles
Publikováno v:
Cancer cell. 31(2)
Small cell lung cancer is initially highly responsive to cisplatin and etoposide but in almost every case becomes rapidly chemoresistant, leading to death within one year. We modeled acquired chemoresistance in vivo using a series of patient-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9488df885368774211b8afddc7b474e0
https://pubmed.ncbi.nlm.nih.gov/28196592
https://pubmed.ncbi.nlm.nih.gov/28196592