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pro vyhledávání: '"Paige Garrison"'
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT African trypanosomes evade the immune system of the mammalian host by the antigenic variation of the predominant glycosylphosphatidylinositol (GPI)-anchored surface protein, variant surface glycoprotein (VSG). VSG is a very stable protein th
Externí odkaz:
https://doaj.org/article/ba2f479967834f469815dce8df5cb963
Autor:
Paige Garrison, Umaer Khan, Michael Cipriano, Peter J. Bush, Jacquelyn McDonald, Aakash Sur, Peter J. Myler, Terry K. Smith, Stephen L. Hajduk, James D. Bangs
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT African trypanosomes utilize glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) to evade the host immune system. VSG turnover is thought to be mediated via cleavage of the GPI anchor by endogenous GPI-specific pho
Externí odkaz:
https://doaj.org/article/bf9bd0020fb4404db69135c5e3a5c6f5
Autor:
Michael J. Cipriano, Umaer Khan, Terry K. Smith, Peter J. Bush, Stephen L. Hajduk, Aakash Sur, Peter J. Myler, Jacquelyn R McDonald, Paige Garrison, James D. Bangs
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
This work was supported by United States Public Health Service grant R01 AI035739 and funds from the Jacobs School of Medicine and Biomedical Sciences to J.D.B. and from United States Public Health Service grant 1S10OD021719-01A1 to the University of
Dissertation/ Thesis
Autor:
Paige, Garrison Danielle
Michael Tillotson’s Agency Reduction Formation theory is designed to expose, situate, and explain ideological trends that are intended to compel African people to distance themselves from their collective identity (Tillotson 2011, 62). Identity pro
Externí odkaz:
http://hdl.handle.net/20.500.12613/280
Publikováno v:
Molecular and Biochemical Parasitology. 245:111409
Glycosylphosphatidylinositol-phospholipase C (GPI-PLC) is an enzyme that has been implicated in GPI-dependent protein trafficking and phosphoinositide metabolism in the bloodstream stage of African trypanosomes. However, despite the fact that it is a
Autor:
Paige Garrison, James D. Bangs
Publikováno v:
Molecular and Biochemical Parasitology. 239:111313
Misfolded proteins trapped in the endoplasmic reticulum (ER) are specifically recognized and retrotranslocated to the cytosol by the ER-Associated Degradation (ERAD) system and delivered to the proteasome for destruction. This process was recently de