Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pagona, Oikonomou"'
Autor:
Fotini Kostopoulou, Vasiliki Gkretsi, Konstantinos N Malizos, Dimitrios Iliopoulos, Pagona Oikonomou, Lazaros Poultsides, Aspasia Tsezou
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35753 (2012)
Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating
Externí odkaz:
https://doaj.org/article/d5da84d7baf848c6b3e548bb4a4a104e
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3740 (2008)
BACKGROUND: Osteoarthritis is a multifactorial disease characterized by destruction of the articular cartilage due to genetic, mechanical and environmental components affecting more than 100 million individuals all over the world. Despite the high pr
Externí odkaz:
https://doaj.org/article/26c6598819c44af3b37d363cd49769d1
The catabolic role of toll-like receptor 2 (TLR-2) mediated by the NF-κB pathway in septic arthritis
Autor:
Konstantinos N. Malizos, Aspasia Tsezou, Ioanna V. Papathanasiou, Theofilos Karachalios, Pagona Oikonomou, Lazaros Poultsides
Publikováno v:
Journal of Orthopaedic Research. 29:247-251
Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial components. Our objective was to investigate the role of TLR-2 mediated by the NF-κB pathway in septic arthritic chondrocytes. TLR-1, -2, and -6 mRNA
Publikováno v:
Journal of Orthopaedic Research. 26:136-140
Genetic factors have been shown to play an important role in the etiology of osteoarthritis (OA). A functional single nucleotide polymorphism (SNP) +104T/C; rs143383 in the 5' UTR of the GDF5 gene was recently associated with susceptibility to osteoa
Autor:
Aspasia Tsezou, Nikolaos Papadoulis, Danai Abazis-Stamboulieh, Panayiotis Panayiotidis, Efimia Vrakidou, Pagona Oikonomou
Publikováno v:
Leukemia & Lymphoma. 48:2196-2203
Interleukin-1 (IL-1) is a cytokine involved in the maturation and proliferation of B cells and plays a significant role in the development of lytic bone lesions, a major clinical feature of multiple myeloma (MM) patients. Genes that regulate products
Publikováno v:
Human Pathology. 37:135-142
Expression of human telomerase reverse transcriptase (hTERT) messenger RNA (mRNA) and human papillomavirus (HPV)-16 load were quantified using real-time polymerase chain reaction and correlated with cytological findings and the presence of HPV infect
Autor:
P. Kollia, Pagona Oikonomou, Ioannis E. Messinis, Iordanis Mademtzis, N. Vamvakopoulos, Aspasia Tsezou, Evanthia Kostopoulou
Publikováno v:
Experimental Biology and Medicine. 230:263-270
Telomerase activity and human telomerase reverse transcriptase (hTERT) mRNA expression were investigated in cervical specimens and were correlated with cytologic findings and the presence of human papilloma virus (HPV) infection. Telomerase activity
Autor:
F. Kostopoulou, Dimitrios Iliopoulos, Vasiliki Gkretsi, Pagona Oikonomou, Aspasia Tsezou, Konstantinos N. Malizos, Lazaros Poultsides
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35753 (2012)
PLoS ONE
PLoS ONE
Background Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors
Publikováno v:
Oncology reports. 22(1)
DNA hypermethylation occurs during the multistep process of cervical carcinogenesis. We investigated whether the methylation status in the promoter region of a potential oncogene, the human telomerase reverse transcriptase (hTERT), and the tumor supp
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 232(7)
Human telomerase reverse transcriptase (hTERT) mRNA expression seems to play an important role in cervical carcinogenesis. Analysis of the hTERT promoter region revealed the presence of a CpG island and a high overall GC content, suggesting a possibl