Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Page C. Spiess"'
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 265-275 (2013)
Cigarette smoking remains a major health concern worldwide, and many of the adverse effects of cigarette smoke (CS) can be attributed to its abundant electrophilic aldehydes, such as acrolein (2-propenal). Previous studies indicate that acrolein read
Externí odkaz:
https://doaj.org/article/142586c60b7b406f82c034df28d3ad1f
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 265-275 (2013)
Redox Biology
Redox Biology
Cigarette smoking remains a major health concern worldwide, and many of the adverse effects of cigarette smoke (CS) can be attributed to its abundant electrophilic aldehydes, such as acrolein (2-propenal). Previous studies indicate that acrolein read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075c5c7c06c7dbe271d39a171701b93b
https://doi.org/10.1016/j.redox.2013.02.001
https://doi.org/10.1016/j.redox.2013.02.001
Publikováno v:
Journal of Proteomics. 74:2380-2394
Acrolein (2,3-propenal) is a major indoor and outdoor air pollutant originating largely from tobacco smoke or organic combustion. Given its high reactivity, the adverse effects of inhaled acrolein are likely due to direct interactions with the airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29113a09d11600ecd23960888fd23f01
https://doi.org/10.1016/j.jprot.2011.05.039
https://doi.org/10.1016/j.jprot.2011.05.039
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 43:316-325
Naphthalene (NA) is a semivolatile aromatic hydrocarbon to which humans are exposed from a variety of sources. NA results in acute cytotoxicity to respiratory epithelium in rodents. Cytochrome P450-dependent metabolic activation to form reactive inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ea8f0fa15f26862537da412030446e
https://doi.org/10.1165/rcmb.2009-0135oc
https://doi.org/10.1165/rcmb.2009-0135oc
Publikováno v:
Chemical Research in Toxicology. 21:1074-1085
The significance of free radicals in biology has been established by numerous investigations spanning a period of over 40 years. Whereas there are many intracellular targets for these radical species, the importance of cysteine thiol posttranslationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd85506444a6fb77c46b6666b87882e
https://doi.org/10.1021/tx8000708
https://doi.org/10.1021/tx8000708
Autor:
Milena Hristova, Matthew J. Randall, Matthew E. Poynter, Robert A. Bauer, Aida Habibovic, Edmund O'Brien, Albert van der Vliet, Page C. Spiess
Acrolein (ACR), an α,β-unsaturated aldehyde and a major component of tobacco smoke, is a highly reactive electrophilic respiratory irritant implicated in asthma pathogenesis and severity. However, few studies have directly investigated the influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81554bca778fdad3488626702c7c4cb
https://europepmc.org/articles/PMC4678038/
https://europepmc.org/articles/PMC4678038/
Autor:
Sameer Kaiser, Arti Shukla, Albert Emery, Page C. Spiess, Christopher C. Landry, Ted A. James, Maximilian B. MacPherson, Albert van der Vliet
Publikováno v:
Cancer Nanotechnology
Introduction Five year survival for metastatic melanoma (MM) is very low at Methods In vitro experiments were performed to assess docetaxel loading onto APMS-TEG particles and release kinetics. Toxicity experiments were performed using docetaxel and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d829251b61363bb4aeb5bb60fbef0eef
http://europepmc.org/articles/PMC4305083
http://europepmc.org/articles/PMC4305083
Publikováno v:
Environmental Health Perspectives
Red tides have been documented on the Gulf Coast of Florida as early as 1530 (Taylor 1917). They occur almost annually and often persist for many months (Woodcock 1948). Red tides are caused by the dinoflagellate Karenia brevis (formerly Gymnodinium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89af72b47b016863a6064bf498d1e056
https://doi.org/10.1289/ehp.8010
https://doi.org/10.1289/ehp.8010
Autor:
Brooke T. Mossman, Maximilian B. MacPherson, Page C. Spiess, Nicholas H. Heintz, Catherine M. Westbom, Joyce K. Thompson, Arti Shukla
Publikováno v:
Particle and Fibre Toxicology
Background Asbestos exposure is related to various diseases including asbestosis and malignant mesothelioma (MM). Among the pathogenic mechanisms proposed by which asbestos can cause diseases involving epithelial and mesothelial cells, the most widel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d9ed7d45e540311c9d65956ae6b124
https://doi.org/10.1186/1743-8977-11-24
https://doi.org/10.1186/1743-8977-11-24
Autor:
Matthew J. Randall, Milena Hristova, Matthew E. Poynter, Albert van der Vliet, Page C. Spiess, Aida Habibovic, David I. Kasahara
Publikováno v:
Respiratory Research
BackgroundAdverse health effects of tobacco smoke arise partly from its influence on innate and adaptive immune responses, leading to impaired innate immunity and host defense. The impact of smoking on allergic asthma remains unclear, with various re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3180af2835bbcc25e9f4d539abcaf1
https://doi.org/10.1186/1465-9921-14-107
https://doi.org/10.1186/1465-9921-14-107