GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.

Autor: Shade LMP; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA., Katsumata Y; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA., Abner EL; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Epidemiology and Environmental Health, College of Public Health, University of Kentucky, Lexington, KY, USA., Aung KZ; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA., Claas SA; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA., Qiao Q; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA., Heberle BA; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, USA., Brandon JA; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, USA., Page ML; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Mukherjee S; Department of Medicine, University of Washington, Seattle, WA, USA., Mayeux RP; Department of Neurology, Columbia University, New York City, NY, USA., Farrer LA; Department of Medicine (Biomedical Genetics), Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA.; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.; Department of Epidemiology, School of Public Health, Boston University, Boston, MA, USA., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Penn Neurodegeneration Genomics Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Haines JL; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Kukull WA; National Alzheimer's Coordinating Center, Department of Epidemiology, University of Washington, Seattle, WA, USA., Nho K; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA., Saykin AJ; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA., Bennett DA; Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush Medical College, Chicago, IL, USA., Schneider JA; Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush Medical College, Chicago, IL, USA.; Department of Pathology, Rush Medical College, Chicago, IL, USA., Ebbert MTW; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, USA.; Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY, USA., Nelson PT; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA.; Department of Pathology and Laboratory Medicine, University of Kentucky College of Medicine, Lexington, KY, USA., Fardo DW; Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA. david.fardo@uky.edu.; Sanders-Brown Center on Aging and Alzheimer's Disease Research Center, University of Kentucky, Lexington, KY, USA. david.fardo@uky.edu.

Publikováno v: Nature genetics [Nat Genet] 2024 Nov; Vol. 56 (11), pp. 2407-2421. Date of Electronic Publication: 2024 Oct 08.

Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq.

Autor: Aguzzoli Heberle B; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, USA., Brandon JA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Page ML; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Nations KA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Dikobe KI; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., White BJ; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Gordon LA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Fox GA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, USA., Wadsworth ME; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Doyle PH; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, USA., Williams BA; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA., Fox EJ; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Shantaraman A; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA., Ryten M; UK Dementia Research Institute at The University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK., Goodwin S; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Ghiban E; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Wappel R; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Mavruk-Eskipehlivan S; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Miller JB; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Division of Biomedical Informatics, Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, USA.; Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, KY, USA., Seyfried NT; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Nelson PT; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA., Fryer JD; Department of Neuroscience, Mayo Clinic, Scottsdale, AZ, USA., Ebbert MTW; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA. mark.ebbert@uky.edu.; Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, USA. mark.ebbert@uky.edu.; Division of Biomedical Informatics, Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA. mark.ebbert@uky.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2024 May 22. Date of Electronic Publication: 2024 May 22.

Evidence of exploitative competition between honey bees and native bees in two California landscapes.

Autor: Page ML; Department of Entomology and Nematology, University of California, Davis, California, USA.; Department of Entomology, Cornell University, Ithaca, New York, USA., Williams NM; Department of Entomology and Nematology, University of California, Davis, California, USA.

Publikováno v: The Journal of animal ecology [J Anim Ecol] 2023 Sep; Vol. 92 (9), pp. 1802-1814. Date of Electronic Publication: 2023 Jun 29.

Myositis with prominent B cell aggregates may meet classification criteria for sporadic inclusion body myositis.

Autor: Meyer A; Exploration fonctionnelle musculaire, Service de physiologie, Service de rhumatologie, Centre de références des maladies autoimmunes rares, Hôpitaux universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France. Electronic address: alain.meyer1@chru-strasbourg.fr., Troyanov Y; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Rheumatology, Hôpital du Sacré-Coeur, Montreal, Québec, Canada., Korathanakhun P; Department of Neurology, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada., Landon-Cardinal O; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Montreal, Québec, Canada; CHUM Research Center, Montreal, Québec, Canada., Leclair V; Department of Medicine, McGill University, Montreal, Québec, Canada; Division of Rheumatology, Jewish General Hospital, Montreal, Québec, Canada., Allard-Chamard H; Department of Medicine, Sherbrooke University, Sherbrooke, Québec, Canada; Division of Rheumatology, CHUS, Sherbrooke, Québec, Canada., Bourré-Tessier J; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Montreal, Québec, Canada; CHUM Research Center, Montreal, Québec, Canada., Makhzoum JP; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Internal Medicine, Hôpital du Sacré-Coeur, Montreal, Québec, Canada., Isabelle C; Department of Medicine, Sherbrooke University, Sherbrooke, Québec, Canada; Division of Rheumatology, Hôpital Charles-Lemoyne, Longueuil, Québec, Canada., Larue S; Department of Medicine, Sherbrooke University, Sherbrooke, Québec, Canada; Division of Neurology, Hôpital Charles-Lemoyne, Longueuil, Québec, Canada., Grand'Maison F; Department of Medicine, Sherbrooke University, Sherbrooke, Québec, Canada; Division of Neurology, Hôpital Charles-Lemoyne, Longueuil, Québec, Canada., Massie R; Department of Neurology, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada., Page ML; Division of Rheumatology, Centre hospitalier régional de Lanaudière, Saint-Charles-Borromée, Québec, Canada., Mansour AM; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Internal Medicine, Hôpital du Sacré-Coeur, Montreal, Québec, Canada., Routhier N; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Internal Medicine, Hôpital du Sacré-Coeur, Montreal, Québec, Canada., Zarka F; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Internal Medicine, Hôpital du Sacré-Coeur, Montreal, Québec, Canada., Roy F; Department of Medicine, University of Montreal, Montreal, Québec, Canada., Sonnen J; Department of Neurology, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada; Department of Pathology, McGill University, Montreal, Québec, Canada., Satoh M; Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan., Fritzler M; Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Hudson M; Department of Medicine, McGill University, Montreal, Québec, Canada; Division of Rheumatology, Jewish General Hospital, Montreal, Québec, Canada; Lady Davis Institute, Jewish General Hospital, Montreal, Québec, Canada., Senécal JL; Department of Medicine, University of Montreal, Montreal, Québec, Canada; Division of Rheumatology, Centre hospitalier de l'Université de Montréal, Montreal, Québec, Canada; CHUM Research Center, Montreal, Québec, Canada., Karamchandani J; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada; Department of Pathology, McGill University, Montreal, Québec, Canada., Ellezam B; Department of Pathology and Cell Biology, University of Montreal, Montreal, Québec, Canada; Department of Pathology, Hôpital Sainte-Justine, Montreal, Québec, Canada., O'Ferrall E; Department of Neurology, McGill University, Montreal, Québec, Canada; Montreal Neurological Institute and Hospital, Montreal, Québec, Canada; Department of Pathology, McGill University, Montreal, Québec, Canada.

Publikováno v: Neuromuscular disorders : NMD [Neuromuscul Disord] 2023 Feb; Vol. 33 (2), pp. 169-182. Date of Electronic Publication: 2022 Dec 05.

Yoga and the Healing of Interpersonal Trauma: A Qualitative Meta-Analysis.

Autor: Ong Gaffney I; Independent Researcher., Gulden AW; North Memorial Health, Robbinsdale, Minn., Jennings L; Graduate School of Professional Psychology, University of St. Thomas., Page ML; Graduate School of Professional Psychology, University of St. Thomas.

Publikováno v: International journal of yoga therapy [Int J Yoga Therap] 2023 Jan 01; Vol. 33 (2023).