Translating the potential of the urine steroid metabolome to stage NAFLD (TrUSt-NAFLD): study protocol for a multicentre, prospective validation study

Autor: David Sheridan, Jeremy F Cobbold, Jeremy W Tomlinson, William Alazawi, Richard Parker, Alice J Sitch, Fredrik Karpe, David Harman, Hamish Miller, Márta Korbonits, Philip N Newsome, Guruprasad Padur Aithal, Pinelopi Manousou, Wiebke Arlt, Matthew Neville, Michael Biehl

Publikováno v: BMJ Open, Vol 14, Iss 1 (2024)

Introduction Non-alcoholic fatty liver disease (NAFLD) affects approximately one in four individuals and its prevalence continues to rise. The advanced stages of NAFLD with significant liver fibrosis are associated with adverse morbidity and mortalit

Externí odkaz: https://doaj.org/article/c214c03f55b64cb2948ce7f6c0914dce

Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification

Autor: Lara C. Lewis, Peggy Cho Kiu Lo, Jeremy M. Foster, Nan Dai, Ivan R. Corrêa, Paulina M. Durczak, Gary Duncan, Ashley Ramsawhook, Guruprasad Padur Aithal, Chris Denning, Nicholas R. F. Hannan, Alexey Ruzov

Publikováno v: Epigenetics, Vol 12, Iss 4, Pp 277-286 (2017)

Patterns of DNA methylation (5-methylcytosine, 5mC) are rearranged during differentiation contributing to the regulation of cell type-specific gene expression. TET proteins oxidize 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-

Externí odkaz: https://doaj.org/article/20cafdd844e340c596c7cad776addb54

A cadaveric study of variations of external iliac artery and its implication in trauma and radiology

Autor: Deepthinath Regunathan, Nayanatara Arun Kumar, A. Padur Aithal, P. Alathady Maloor, S.B. Badagabettu Nayak, Prasanna Kumar Shetty

Publikováno v: Morphologie. 103:24-31

Summary Objectives A severe and potentially lethal complication in pelvic injuries is arterial bleeding commonly involving the iliac arteries. Hence, the objective of our study was to systematically document the morphology and variations of the exter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf722ebab330ea24baf05523c99e942
https://doi.org/10.1016/j.morpho.2018.10.001

Treatment and Outcome of Autoimmune Hepatitis (AIH): Audit of 28 UK Centres

Autor: Victoria Gordon, Ratul Adhikary, Victoria Appleby, Debasish Das, James Day, Toby Delahooke, Selena Dixon, David Elphick, Claire Hardie, Michael A. Heneghan, Barbara Hoeroldt, Patricia Hooper, John Hutchinson, Rebecca Jones, Faisal Khan, Guruprasad Padur Aithal, Jane Metcalf, Alick Nkhoma, Stavroula Pelitari, Martin Prince, Annell Prosser, Vinay Sathanarayana, Sushma Saksena, Deven Vani, Andrew Yeoman, George Abouda, Andrew Nelson, Dermot Gleeson, UK Multi-Centre AIH Audit Group

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac944f3ba322763788a19c91b61aa847
https://doi.org/10.2139/ssrn.3927062

Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

Autor: Emmanuel Anandraj Selvaraj, Ferenc Emil Mózes, Arjun Narayan Ajmer Jayaswal, Mohammad Hadi Zafarmand, Yasaman Vali, Jenny A. Lee, Christina Kim Levick, Liam Arnold Joseph Young, Naaventhan Palaniyappan, Chang-Hai Liu, Guruprasad Padur Aithal, Manuel Romero-Gómez, M. Julia Brosnan, Theresa A. Tuthill, Quentin M. Anstee, Stefan Neubauer, Stephen A. Harrison, Patrick M. Bossuyt, Michael Pavlides, Quentin Anstee, Ann Daly, Katherine Johnson, Olivier Govaere, Simon Cockell, Dina Tiniakos, Pierre Bedossa, Fiona Oakley, Heather Cordell, Chris Day, Kristy Wonders, Patrick Bossuyt, Hadi Zafarmand, Jenny Lee, Vlad Ratziu, Karine Clement, Raluca Pais, Detlef Schuppan, Jörn Schattenberg, Toni Vidal-Puig, Michele Vacca, Sergio Rodrigues-Cuenca, Mike Allison, Ioannis Kamzolas, Evangelia Petsalaki, Matej Oresic, Tuulia Hyötyläinen, Aiden McGlinchey, Jose M. Mato, Oscar Millet, Jean-François Dufour, Annalisa Berzigotti, Stephen Harrison, Jeremy Cobbold, Ferenc Mozes, Salma Akhtar, Rajarshi Banerjee, Matt Kelly, Elizabeth Shumbayawonda, Andrea Dennis, Charlotte Erpicum, Emilio Gómez-González, Javier Ampuero, Javier Castell, Rocío Gallego-Durán, Isabel Fernández, Rocío Montero-Vallejo, Morten Karsdal, Elisabeth Erhardtsen, Daniel Rasmussen, Diana Julie Leeming, Mette Juul Fisker, Antonia Sinisi, Kishwar Musa, Fay Betsou, Estelle Sandt, Manuela Tonini, Elisabetta Bugianesi, Chiara Rosso, Angelo Armandi, Fabio Marra, Amalia Gastaldelli, Gianluca Svegliati, Jérôme Boursier, Sven Francque, Luisa Vonghia, Mattias Ekstedt, Stergios Kechagias, Hannele Yki-Jarvinen, Panu Luukkonen, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Luca Valenti, Salvatore Petta, Luca Miele, Andreas Geier, Christian Trautwein, Guru Aithal, Paul Hockings, Philip Newsome, David Wenn, Cecília Maria Pereira Rodrigues, Pierre Chaumat, Rémy Hanf, Aldo Trylesinski, Pablo Ortiz, Kevin Duffin, Julia Brosnan, Theresa Tuthill, Euan McLeod, Judith Ertle, Ramy Younes, Rachel Ostroff, Leigh Alexander, Mette Skalshøi Kjær, Lars Friis Mikkelsen, Maria-Magdalena Balp, Clifford Brass, Lori Jennings, Miljen Martic, Juergen Loeffler, Guido Hanauer, Sudha Shankar, Céline Fournier, Kay Pepin, Richard Ehman, Joel Myers, Gideon Ho, Richard Torstenson, Rob Myers, Lynda Doward

Publikováno v: Journal of hepatology
J Hepatol
Journal of hepatology, 75(4), 770-785. Elsevier
Digital.CSIC. Repositorio Institucional del CSIC
instname

[Background and Aims] Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic resonance elastography (MRE), and magnetic resonance imaging (MRI) have been propo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948de6fb35a479446181515de02296f2