Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Padrig B. Flynn"'
Autor:
Jordanne-Amee Maybin, Thomas P. Thompson, Padrig B. Flynn, Timofey Skvortsov, Noreen J. Hickok, Theresa A. Freeman, Brendan F. Gilmore
Publikováno v:
Biofilm, Vol 5, Iss , Pp 100122- (2023)
Cold atmospheric-pressure plasma (CAP) has emerged as a potential alternative or adjuvant to conventional antibiotics for the treatment of bacterial infections, including those caused by antibiotic-resistant pathogens. The potential of sub-lethal CAP
Externí odkaz:
https://doaj.org/article/960d787fd4364b89b705c558d3ebe4c5
Autor:
Ewa Wielogorska, Padrig B. Flynn, Julie Meneely, Thomas P. Thompson, William G. Graham, Brendan F. Gilmore, Christopher T. Elliott
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1115 (2023)
The presence of antibiotic residues in water is linked to the emergence of antibiotic resistance globally and necessitates novel decontamination strategies to minimize antibiotic residue exposure in both the environment and food. A holistic assessmen
Externí odkaz:
https://doaj.org/article/d14646ffaf7d46b3af5c0d7cad8e49a6
Autor:
Elliott, Ewa Wielogorska, Padrig B. Flynn, Julie Meneely, Thomas P. Thompson, William G. Graham, Brendan F. Gilmore, Christopher T.
Publikováno v:
Antibiotics; Volume 12; Issue 7; Pages: 1115
The presence of antibiotic residues in water is linked to the emergence of antibiotic resistance globally and necessitates novel decontamination strategies to minimize antibiotic residue exposure in both the environment and food. A holistic assessmen
Autor:
Padrig B. Flynn, Nida Alshraiedeh, Michael M. Tunney, Brendan Gilmore, Thomas P. Thompson, Stephen A. Kelly
Publikováno v:
Alshraiedeh, N H, Kelly, S A, Thompson, T P, Flynn, P B, Tunney, M M & Gilmore, B F 2020, ' Extracellular polymeric substance-mediated tolerance of Pseudomonas aeruginosa biofilms to atmospheric pressure nonthermal plasma treatment ', Plasma Processes and Polymers, vol. 17, no. 12, 2000108 . https://doi.org/10.1002/ppap.202000108
Pseudomonas aeruginosa is an opportunistic disease-causing bacterium, with a number of strains exhibiting a mucus-forming (mucoid) phenotype during infection, producing biofilms with a surrounding matrix containing alginate. Atmospheric pressure nont
Autor:
Noreen J. Hickok, Paula Bourke, Padrig B. Flynn, Seamus O'Brien, Brendan Gilmore, Theresa A. Freeman
Publikováno v:
Trends in biotechnology. 36(6)
Bacterial biofilm infections account for a major proportion of chronic and medical device associated infections in humans, yet our ability to control them is compromised by their inherent tolerance to antimicrobial agents. Cold atmospheric plasma (CA
Autor:
William Graham, Nida Alshraiedeh, Padrig B. Flynn, Sean P. Gorman, Brendan Gilmore, Sarah Higginbotham
Publikováno v:
International Journal of Antimicrobial Agents. 46:101-107
The emergence of multidrug-resistant pathogens within the clinical environment is presenting a mounting problem in hospitals worldwide. The ‘ESKAPE’ pathogens ( Enterococcus faecium , Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter
Autor:
Mairéad Connor, Padrig B. Flynn, Derek J. Fairley, Nikki Marks, Panagiotis Manesiotis, William G. Graham, Brendan F. Gilmore, John W. McGrath
Publikováno v:
Scientific Reports
Clostridium difficile is a spore forming bacterium and the leading cause of colitis and antibiotic associated diarrhoea in the developed world. Spores produced by C. difficile are robust and can remain viable for months, leading to prolonged healthca
Autor:
William Graham, Padrig B. Flynn, Mahmoud Y. Alkawareek, Nida Alshraiedeh, Sean P. Gorman, Qais Th. Algwari, Sarah Higginbotham, Brendan Gilmore
Publikováno v:
Plasma Medicine. 4:211-219
The nature and kinetics of plasmid DNA damage after DNA exposure to a kHz-driven atmospheric pressure nonthermal plasma jet has been investigated. Both single-strand break (SSB) and double-strand break (DSB) processes are reported here. While SSB had
Autor:
Padrig B. Flynn, Muna Barakat, Louise Carson, Yahya H. Dallal Bashi, Brendan Gilmore, William Graham
Publikováno v:
Microbial Pathogenesis. 136:103679
Lipopolysaccharide (LPS) is an endotoxin composed of a polysaccharide and lipid component. It is intrinsically responsible for the pathogenicity of Gram-negative bacteria and is involved in the development of bacterial sepsis. Atmospheric pressure no
Autor:
Padrig B. Flynn, Alessandro Busetti, Ewa Wielogorska, Olivier P. Chevallier, Christopher T. Elliott, Garry Laverty, Sean P. Gorman, William G. Graham, Brendan F. Gilmore
Publikováno v:
Scientific Reports
Flynn, P, Busetti, A, Wielogorska, E, Chevallier, O P, Elliott, C T, Laverty, G, Gorman, S, Graham, W G & Gilmore, B F 2016, ' Non-thermal Plasma Exposure Rapidly Attenuates Bacterial AHL-Dependent Quorum Sensing and Virulence. ', Scientific Reports, vol. 6, 26320 . https://doi.org/10.1038/srep26320
Flynn, P, Busetti, A, Wielogorska, E, Chevallier, O P, Elliott, C T, Laverty, G, Gorman, S, Graham, W G & Gilmore, B F 2016, ' Non-thermal Plasma Exposure Rapidly Attenuates Bacterial AHL-Dependent Quorum Sensing and Virulence. ', Scientific Reports, vol. 6, 26320 . https://doi.org/10.1038/srep26320
The antimicrobial activity of atmospheric pressure non-thermal plasma has been exhaustively characterised, however elucidation of the interactions between biomolecules produced and utilised by bacteria and short plasma exposures are required for opti