Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Padraic Fallon"'
Publikováno v:
Experimental Gerontology, Vol 183, Iss , Pp 112314- (2023)
Metabolic syndrome (MetS) is a risk factor for the development of diabetes, cardiovascular disease, and all-cause mortality. It has an estimated prevalence of 40 % among older adults. Epigenetic clocks, which measure biological age based on DNA methy
Externí odkaz:
https://doaj.org/article/555851f0f2ae4c3e80b9f34e31a0925a
Autor:
Clive Drakeford, Sonia Aguila, Fiona Roche, Karsten Hokamp, Judicael Fazavana, Mariana P. Cervantes, Annie M. Curtis, Heike C. Hawerkamp, Sukhraj Pal Singh Dhami, Hugo Charles-Messance, Emer E. Hackett, Alain Chion, Soracha Ward, Azaz Ahmad, Ingmar Schoen, Eamon Breen, Joe Keane, Ross Murphy, Roger J. S. Preston, Jamie M. O’Sullivan, Frederick J. Sheedy, Padraic Fallon, James S. O’Donnell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
von Willebrand factor (VWF) plays a critical role in primary hemostasis following vascular injury by tethering platelets to exposed collagen. Here, VWF binding to macrophages is shown to trigger NF-κB activation and induce pro-inflammatory responses
Externí odkaz:
https://doaj.org/article/0abf998c232d43bcab767dde021ae471
Autor:
Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Román Romero Ortuño, Rose Anne Kenny
Publikováno v:
Experimental Gerontology, Vol 172, Iss , Pp 112056- (2023)
Objectives: Metabolic syndrome (MetS) is a risk factor for cardiovascular disease, diabetes, and all-cause mortality. Frailty is a condition of decreased multi-system physiological reserve where one has increased vulnerability to stressors. This stud
Externí odkaz:
https://doaj.org/article/632a53b8f09947eb8260fe54ce879a26
Autor:
Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Cathal Walsh, Martin Healy, Annette L. Fitzpatrick, James B. Walsh, Belinda Hernández, Padraic Fallon, Anne M. Molloy, Rose Anne Kenny
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101654- (2022)
Summary: Background: It is hypothesized that vitamin D contributes to the aetiology of type 2 diabetes mellitus (diabetes). This study's objective was to examine the relationships between baseline vitamin D status (as measured by plasma 25-hydroxyvit
Externí odkaz:
https://doaj.org/article/cd7f862cb96a49bbb72994ed1a615f18
Autor:
Clíona Ní Cheallaigh, Laura O'Doherty, Nicole Wood, Stuart Hendricken Phelan, Jacklyn Sui, Sorcha O'Brien, Fergal Howley, Cian Mangan, Noor Adeebah Mohamed Razif, Siobhan O'Regan, Ruth Argue, Ciara Conlan, Adam Dyer, Samuel Holohan, Roman Romero-Ortuno, Liam Townsend, Fara Salleh, Colm Kerr, Gerard Hughes, Alberto Sanz, Derval Reidy, Andrea Kelly, Emma Connolly, Siobhan Gargan, Conor Reddy, Heike Hawerkamp, Eamon Breen, Ignacio Martin-Loeches, Jean Dunne, Aideen Long, Anne Marie McLaughlin, Padraic Fallon, Orla Shiels, Ciaran Bannan, Martina Hennessy, Ana Rakovac, Anna Rose Prior, Ross McManus, William McCormack, Colm Bergin, Seamus Donnelly, Mark Little, Emma Leacy, Niall Conlon
Publikováno v:
HRB Open Research, Vol 5 (2022)
Background: The current coronavirus disease 2019 (COVID-19) pandemic began in Ireland with the first confirmed positive case in March 2020. In the early stages of the pandemic clinicians and researchers in two affiliated Dublin hospitals identified t
Externí odkaz:
https://doaj.org/article/f3611967469d4829b773b45897958a77
Autor:
Kevin McCarthy, Eamon Laird, Aisling M. O’Halloran, Padraic Fallon, Deirdre O’Connor, Román Romero Ortuño, Rose Anne Kenny
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Metabolic syndrome (MetS) consists of the cluster of central obesity, insulin resistance, hypertension and atherogenic dyslipidaemia. It is a risk factor for cardiovascular disease, diabetes, and mortality. The prevalence of MetS has not been describ
Externí odkaz:
https://doaj.org/article/7db1a57a67b9468b84e79919669cc563
Autor:
Stéphanie Lavazais, Manja Jargosch, Sonia Dupont, Frédéric Labéguère, Christel Menet, Catherine Jagerschmidt, Frenz Ohm, Laszlo Kupcsik, Isabelle Parent, Céline Cottereaux, Florence Marsais, Line Oste, An Van de Water, Thierry Christophe, Steve De Vos, Padraic Fallon, Felix Lauffer, Philippe Clément-Lacroix, Kilian Eyerich, Reginald Brys
Publikováno v:
Science Translational Medicine. 15
Innate immunity not only shapes the way epithelial barriers interpret environmental cues but also drives adaptive responses. Therefore, modulators of innate immune responses are expected to have high therapeutic potential across immune-mediated infla
Autor:
Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Padraic Fallon, Román Romero Ortuño, Rose Anne Kenny
Publikováno v:
Experimental gerontology. 172
Metabolic syndrome (MetS) is a risk factor for cardiovascular disease, diabetes, and all-cause mortality. Frailty is a condition of decreased multi-system physiological reserve where one has increased vulnerability to stressors. This study aimed to e
Autor:
K Eyerich, Reginald Brys, Felix Lauffer, Philippe Clément-Lacroix, Padraic Fallon, Catherine Jagerschmidt, Frenz Ohm, Stéphanie Lavazais, Manja Jargosch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f4ce05d977b33aebb8a37ce9aebdb3e
https://doi.org/10.26226/m.62fa009c7fa14e00183c0f8f
https://doi.org/10.26226/m.62fa009c7fa14e00183c0f8f
Autor:
Laura O'Doherty, Stuart Hendricken Phelan, Nicole Wood, Sorcha O'Brien, Jacklyn Sui, Cian Mangan, Fergal Howley, Siobhan O'Regan, Noor Adeebah Mohamed Razif, Ciara Conlan, Ruth Argue, Samuel Holohan, Adam Dyer, Fara Salleh, Liam Townsend, Gerard Hughes, Colm Kerr, Derval Reidy, Alberto Sanz, Emma Connolly, Andrea Kelly, Emma Leacy, Conor Reddy, Siobhan Gargan, Eamon Breen, Heike Hawerkamp, Jean Dunne, Ignacio Martin-Loeches, Anne Marie McLaughlin, Aideen Long, Orla Shiels, Padraic Fallon, Martina Hennessy, Roman Romero-Ortuno, Ciaran Bannan, Anna Rose Prior, Ana Rakovac, William McCormack, Ross McManus, Seamus Donnelly, Colm Bergin, Mark Little, Clíona Ní Cheallaigh, Niall Conlon
Publikováno v:
HRB open research. 5
Background: The current coronavirus disease 2019 (COVID-19) pandemic began in Ireland with the first confirmed positive case in March 2020. In the early stages of the pandemic clinicians and researchers in two affiliated Dublin hospitals identified t