A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells

Autor: Elgjo Kjell, Padovini Valentina, De Angelis Paula M, Annulli Lucia, Mancinelli Loretta, Gianfranceschi Gian

Publikováno v: Molecular Cancer, Vol 8, Iss 1, p 55 (2009)

Abstract Background Deproteinized DNA from eukaryotic and prokaryotic cells still contains a low-molecular weight peptidic fraction which can be dissociated by alkalinization of the medium. This fraction inhibits RNA transcription and tumor cell grow

Externí odkaz: https://doaj.org/article/1d0a2e4ae6c54136b1bef804cc16c48d

A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells.

Autor: Mancinelli L; Department of Cellular and Environmental Biology, CEMIN (Center of Excellence on Innovative Nanostructured Materials for chemical, physical and biomedical applications), University of Perugia, Perugia, Italy. loretta@unipg.it, De Angelis PM, Annulli L, Padovini V, Elgjo K, Gianfranceschi GL

Publikováno v: Molecular cancer [Mol Cancer] 2009 Jul 31; Vol. 8, pp. 55. Date of Electronic Publication: 2009 Jul 31.