Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Padmavathi Bandhuvula"'
Autor:
Alexander D. Borowsky, Padmavathi Bandhuvula, Ashok Kumar, Yuko Yoshinaga, Mikhail Nefedov, Loren G. Fong, Meng Zhang, Brian Baridon, Lisa Dillard, Pieter de Jong, Stephen G. Young, David B. West, Julie D. Saba
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1920-1931 (2012)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer. S
Externí odkaz:
https://doaj.org/article/e772a50f7a6e4145b1aa23fcda7480ac
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 12, Pp 2769-2778 (2007)
Sphingosine-1-phosphate (S1P) lyase (SPL) catalyzes the conversion of S1P to ethanolamine phosphate and hexadecenal. This enzyme plays diverse roles in physiology and disease and, thus, may be useful as a disease marker and/or drug target. Unfortunat
Externí odkaz:
https://doaj.org/article/86e3719c83c54762af0097985abd62fa
Autor:
Julie D. Saba, Andrew R. Lee, Robert Bittman, Hoe Sup Byun, Yaqiong Gong, Padmavathi Bandhuvula, Babak Oskouian, Henrik Fyrst
Supplementary Methods, Figures 1-9, Table 1 from Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330cbbbe5d08204be44d159d77ab5eed
https://doi.org/10.1158/0008-5472.22383575
https://doi.org/10.1158/0008-5472.22383575
Autor:
Padmavathi Bandhuvula, Yuko Yoshinaga, Pieter J. de Jong, Mikhail Nefedov, Emilie Degagné, Ashok Kumar Pandurangan, Abeer Eltanawy, Julie D. Saba, Stephen G. Young, Meng Zhang, Loren G. Fong, Ashok Kumar, Robert Bittman, Yasmin Ahmedi
Publikováno v:
The Journal of clinical investigation, vol 124, iss 12
Growing evidence supports a link between inflammation and cancer; however, mediators of the transition between inflammation and carcinogenesis remain incompletely understood. Sphingosine-1-phosphate (S1P) lyase (SPL) irreversibly degrades the bioacti
Autor:
Padmavathi, Bandhuvula1, Upreti, Meenakshi2, Singh, Virendra3, Rao, A. Ramesha1, Singh, Rana P.4, Rath, Pramod C.2
Publikováno v:
Nutrition & Cancer. 2005, Vol. 51 Issue 1, p59-67. 9p.
Autor:
Padmavathi Bandhuvula, Stephen G. Young, Lisa M. Dillard, Julie D. Saba, Pieter J. de Jong, Alexander D. Borowsky, Ashok Kumar, Mikhail Nefedov, Loren G. Fong, Meng Zhang, David B. West, Yuko Yoshinaga, Brian Baridon
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1920-1931 (2012)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid involved in immunity, inflammation, angiogenesis, and cancer. S1P lyase (SPL) is the essential enzyme responsible for S1P degradation. SPL augments apoptosis and is down-regulated in cancer. S
Autor:
Norman Honbo, Padmavathi Bandhuvula, Julie D. Saba, Guanying Wang, Henrik Fyrst, Alexander D. Borowsky, Meng Zhang, Zhu-Qiu Jin, Joel S. Karliner, Lisa M. Dillard
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 300:H1753-H1761
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that promotes cardiomyocyte survival and contributes to ischemic preconditioning. S1P lyase (SPL) is a stress-activated enzyme responsible for irreversible S1P catabolism. We hypothesized that
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 12, Pp 2769-2778 (2007)
Sphingosine-1-phosphate (S1P) lyase (SPL) catalyzes the conversion of S1P to ethanolamine phosphate and hexadecenal. This enzyme plays diverse roles in physiology and disease and, thus, may be useful as a disease marker and/or drug target. Unfortunat
Autor:
Phillip Key, Stephen M. Beverley, Kai Zhang, Fong-Fu Hsu, John Turk, Julie D. Saba, Justine M Pompey, Padmavathi Bandhuvula
Publikováno v:
The EMBO Journal. 26:1094-1104
In most eukaryotes, sphingolipids (SLs) are critical membrane components and signaling molecules. However, mutants of the trypanosomatid protozoan Leishmania lacking serine palmitoyltransferase (spt2−) and SLs grow well, although they are defective
Publikováno v:
Journal of Biological Chemistry. 280:33697-33700
FTY720 is a novel immunomodulatory agent that inhibits lymphocyte trafficking and prevents allograft rejection. FTY720 is phosphorylated in vivo, and the phosphorylated drug acts as agonist for a family of G protein-coupled receptors that recognize s