Imidazopyridine chalcones as potent anticancer agents: Synthesis, single-crystal X-ray, docking, DFT and SAR studies.

Autor: Soumyashree DK; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi, Karnataka, India., Reddy DS; Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Bangalore, Karnataka, India., Nagarajaiah H; Department of Chemistry, School of Applied Sciences, REVA University, Bangalore, Karnataka, India., Naik L; Department of Physics and Electronics, CHRIST University, Bangalore, Karnataka, India., Savanur HM; Department of Chemistry, P. C. Jabin Science College, Hubballi, Karnataka, India., Shilpa CD; Department of Chemistry, School of Applied Sciences, REVA University, Bangalore, Karnataka, India., Sunitha Kumari M; Department of Physics, Yuvaraja's College, University of Mysore, Mysuru, Karnataka, India., Shanavaz H; Department of Chemistry, Faculty of Engineering and Technology, Jain University, Jain Global Campus, Bangalore, Karnataka, India., Padmashali B; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi, Karnataka, India.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Jul; Vol. 356 (7), pp. e2300106. Date of Electronic Publication: 2023 May 19.

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Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme.

Autor: Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.; Department of Biotechnology and Food Technology, Durban University of Technology, Durban, South Africa., Chandrashekharappa S; Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India., Deb PK; Faculty of Pharmacy, Department of Pharmaceutical Sciences, Philadelphia University, Amman, Jordan., Tratrat C; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Pillay M; Department of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban, South Africa., Chopra D; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, India., Al-Shar'i NA; Faculty of Pharmacy, Department of Medicinal Chemistry and Pharmacognosy, Jordan University of Science and Technology, Irbid, Jordan., Hourani W; Faculty of Pharmacy, Department of Pharmaceutical Sciences, Philadelphia University, Amman, Jordan., Dahabiyeh LA; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan., Borah P; Pratiksha Institute of Pharmaceutical Sciences, Guwahati, India., Nagdeve RD; Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur, India., Nayak SK; Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur, India., Padmashali B; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi, India., Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.; Faculty of Medicine, Department of Pharmacology, Minia University, El-Minia, Egypt., Aldhubiab BE; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Attimarad M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Sreeharsha N; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.; Department of Pharmaceutics, Vidya Siri College of Pharmacy, Bangalore, India., Haroun M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Shashikanth S; Department of Studies in Organic Chemistry, University of Mysore, Mysore, India., Mohanlall V; Department of Biotechnology and Food Technology, Durban University of Technology, Durban, South Africa., Mailavaram R; Pharmaceutical Chemistry Division, Sri Vishnu College of Pharmacy, Bhimavaram, India.

Publikováno v: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1472-1487.

Investigation of Antifungal Properties of Synthetic Dimethyl-4-Bromo-1-(Substituted Benzoyl) Pyrrolo[1,2-a] Quinoline-2,3-Dicarboxylates Analogues: Molecular Docking Studies and Conceptual DFT-Based Chemical Reactivity Descriptors and Pharmacokinetics Evaluation.

Autor: Uppar V; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi 591156, Karnataka, India., Chandrashekharappa S; Institute for Stem Cell Science and Regenerative Medicine, NCBS, TIFR, GKVK-Campus Bellary road, Bengaluru 560065, Karnataka, India.; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER) Raebareli, Lucknow (UP) 226002, India., Shivamallu C; Department of Biotechnology & Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education and Research, Mysore 570015, Karnataka, India., P S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER) Raebareli, Lucknow (UP) 226002, India., Kollur SP; Department of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru 570026, Karnataka, India., Ortega-Castro J; Departament de Química, Universitat de les Illes Balears, E-07122 Palma de Malllorca, Spain., Frau J; Departament de Química, Universitat de les Illes Balears, E-07122 Palma de Malllorca, Spain., Flores-Holguín N; Laboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, Chih 31136, Mexico., Basarikatti AI; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi 591156, Karnataka, India., Chougala M; Department of Biotechnology, JSS College of Arts, Commerce and Science (Autonomous), Mysore 570025, Karnataka, India., Mohan M M; Department of Biotechnology & Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education and Research, Mysore 570015, Karnataka, India., Banuprakash G; Department of Chemistry, SJB Institute of Technology, Bengaluru 560060, Kengeri, India., Jayadev; Department of Chemistry, SJB Institute of Technology, Bengaluru 560060, Kengeri, India., Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Department of Biotechnology and Food Technology, Faculty of Applied Sciences, Durban University of Technology, Durban 4001, South Africa., Nandeshwarappa BP; Department of Studies in Chemistry, Shivagangothri, Davangere University, Davangere 577007, Karnataka, India., Veerapur R; Department of Metallurgy and Materials Engineering, Malawi Institute of Technology, Malawi University of Science and Technology, P.O. Box-5916 Limbe, Malawi., Al-Kheraif AA; Dental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi Arabia., Elgorban AM; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Syed A; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Mudnakudu-Nagaraju KK; Department of Biotechnology & Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education and Research, Mysore 570015, Karnataka, India., Padmashali B; Department of Chemistry, School of Basic Science, Rani Channamma University, Belagavi 591156, Karnataka, India., Glossman-Mitnik D; Laboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, Chih 31136, Mexico.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 May 06; Vol. 26 (9). Date of Electronic Publication: 2021 May 06.