Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Padmapriya Sathiyanathan"'
Autor:
Ling Ling, Xiafei Ren, Xue Cao, Afizah Binte Mohd Hassan, Sophia Mah, Padmapriya Sathiyanathan, Raymond A.A. Smith, Clarissa L.L. Tan, Michelle Eio, Rebekah M. Samsonraj, Andre J. van Wijnen, Michael Raghunath, Victor Nurcombe, James H. Hui, Simon M. Cool
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 105-121 (2020)
Summary: Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular hep
Externí odkaz:
https://doaj.org/article/20588c373c4b42dcb4070cc8ac8229d2
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Development of primary open-angle glaucoma (POAG) is associated with the malfunctioning trabecular meshwork (TM). Cell therapy offers great potential for the treatment of POAG, but requires the generation of functional TM cells in
Externí odkaz:
https://doaj.org/article/aac059d43a9c40279c60d7139278c130
Autor:
Haojie Yu, Hong Hwa Lim, Natalia O. Tjokro, Padmapriya Sathiyanathan, Suchitra Natarajan, Tian Wei Chew, Thomas Klonisch, Steven D. Goodman, Uttam Surana, Peter Dröge
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 684-697 (2014)
Maintaining genome integrity requires the accurate and complete replication of chromosomal DNA. This is of the utmost importance for embryonic stem cells (ESCs), which differentiate into cells of all lineages, including germ cells. However, endogenou
Externí odkaz:
https://doaj.org/article/e0c0f79bc2d94e02a34db0d3f595b528
Autor:
Clarissa L.L. Tan, Rebekah M. Samsonraj, Ling Ling, Victor Nurcombe, Padmapriya Sathiyanathan, Alexander Lezhava, Simon M. Cool, Lawrence W. Stanton
Publikováno v:
Stem Cells. 38:1124-1136
Although the application of human mesenchymal stem cells (hMSCs) to repair damaged or diseased tissues has proven relatively effective, both the donor-to-donor variability in ex vivo expansion rates and the maintenance of stemness remain a bottleneck
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f832e9e248ff7cb782dac189599da99c
https://doi.org/10.1002/stem.3203
https://doi.org/10.1002/stem.3203
Autor:
Akshaya Srinivasan, Padmapriya Sathiyanathan, Lu Yin, Tong Ming Liu, Alan Lam, Maanasa Ravikumar, Raymond Alexander Alfred Smith, Han Ping Loh, Ying Zhang, Ling Ling, Say Kong Ng, Yuan Sheng Yang, Alexander Lezhava, James Hui, Steve Oh, Simon M. Cool
Publikováno v:
Cytotherapy. 24(5)
Therapies using mesenchymal stromal cells (MSCs) to treat immune and inflammatory conditions are now at an exciting stage of development, with many MSC-based products progressing to phase II and III clinical trials. However, a major bottleneck in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db4dc234704e0e83862e1635e2dbfe5
https://pubmed.ncbi.nlm.nih.gov/35227601
https://pubmed.ncbi.nlm.nih.gov/35227601
Autor:
Sophia Mah, Michelle Eio, Rebekah M. Samsonraj, Raymond A. A. Smith, Afizah Hassan, Ling Ling, Clarissa L.L. Tan, James Hoi Po Hui, Padmapriya Sathiyanathan, Xue Cao, Andre J. van Wijnen, Simon M. Cool, Victor Nurcombe, Xiafei Ren, Michael Raghunath
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 105-121 (2020)
Stem Cell Reports
Stem Cell Reports
Summary Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c8183789180b15c28e15d335250cbf
Autor:
Simon M. Cool, Padmapriya Sathiyanathan, Rebekah M. Samsonraj, Clarissa L. L. Tan, Ling Ling, Alexander Lezhava, Victor Nurcombe, Lawrence W. Stanton
Publikováno v:
Stem Cells. 38:E7-E8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98acddc305454ab5390d5077a921ec87
https://doi.org/10.1002/stem.3264
https://doi.org/10.1002/stem.3264
Autor:
L. Stanton, Rebekah M. Samsonraj, Xiaohua Lu, Ling Ling, Victor Nurcombe, A. Lezhava, Simon M. Cool, Padmapriya Sathiyanathan, Michelle Eio, Clarissa L.L. Tan
Publikováno v:
Cytotherapy. 22:S197-S198
Background & Aim Extreme donor-to-donor variability in scalability and the maintenance of stemness remain a major bottleneck to the therapeutic application of human mesenchymal stem cells (hMSCs). Current best practice monitors stemness by an array o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be989e8f05d7365226df950a621424c3
https://doi.org/10.1016/j.jcyt.2020.04.064
https://doi.org/10.1016/j.jcyt.2020.04.064
Autor:
Bach Quang Le, Jae Won Choi, Seong-baek Lee, Young Sik Kim, Victor Nurcombe, Ju Woong Jang, Tuan Chun Tan, Simon M. Cool, Jung-Soo Lee, Padmapriya Sathiyanathan
Publikováno v:
Gene. 769:145217
Bone morphogenetic protein 2 (BMP2)-induced bone regeneration is most efficacious when a carrier can deliver the growth factor into the defect site while minimizing off-target effects. The control of BMP2 release by such carriers is proving one of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4983740c722deb2e5c7643a0cbd964
https://doi.org/10.1016/j.gene.2020.145217
https://doi.org/10.1016/j.gene.2020.145217
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
BMC Genomics
BMC Genomics
Background Development of primary open-angle glaucoma (POAG) is associated with the malfunctioning trabecular meshwork (TM). Cell therapy offers great potential for the treatment of POAG, but requires the generation of functional TM cells in vitro to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c97b0a2390122aceb04bb29dd4b642
https://doi.org/10.1186/s12864-017-3758-7
https://doi.org/10.1186/s12864-017-3758-7