Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Padmanabh Pravinchandra Bhatt"'
Publikováno v:
Drug Development and Industrial Pharmacy. 24:919-926
We have assessed the bioadhesive properties of several different mucoadhesive buccal patches. The patches consisted of custom coformulations of silicone polymers and Carbopol 974P. The contact angle of water was measured for each of the test formulat
Publikováno v:
Journal of Controlled Release. 44:43-53
Intravaginal devices (diaphragm and disc) were fabricated from silicone elastomer and evaluated for controlled release of Nonoxynol-9 (N-9). These intravaginal devices have good physical properties and reproducibility. A significant amount of N-9 was
Publikováno v:
Journal of Controlled Release. 43:283-290
Spermicide-releasing disposable vaginal devices were fabricated from silicone elastomer and evaluated for controlled release of Nonoxynol-9 (N-9). The optimal loading dose of N-9 in the diaphragm-shaped barrier device to achieve an appropriate releas
Publikováno v:
Drug Development and Industrial Pharmacy. 23:239-246
Mucoadhesive buccal patches were evaluated in vitro and in vivo using rats for release of thyrotropin-releasing homne (TRH). TRH (10% w/w) was incorporated into mucoadhesive buccal patches that were custom coformulated with silicone and organic polym
Publikováno v:
Pharmaceutical development and technology. 2(3)
A biocompatible, mucoadhesive buccal patch was evaluated in rabbits for transmucosal delivery of peptides. Oxytocin (OT) was incorporated into custom coformulations of Carbopol 974P and silicone polymer and the resulting plasma OT concentration versu
Publikováno v:
Pharmaceutical development and technology. 1(4)
A biocompatible, mucoadhesive patch was evaluated for potential use in the delivery of peptides. The model peptide oxytocin was incorporated into the polymeric patch matrix and the diffusion of oxytocin across excised rabbit buccal epithelium was stu