Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Padma S Rajagopal"'
Autor:
Piyush Agrawal, Navami Jain, Vishaka Gopalan, Annan Timon, Arashdeep Singh, Padma S. Rajagopal, Sridhar Hannenhalli
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109752- (2024)
Summary: Breast cancers (BRCA) exhibit substantial transcriptional heterogeneity, posing a significant clinical challenge. The global transcriptional changes in a disease context, however, are likely mediated by few key genes which reflect disease et
Externí odkaz:
https://doaj.org/article/bc76f4e91ec44d41abab0ce488f6be49
Autor:
Siddhartha P. Kar, Daniel P.C. Considine, Jonathan P. Tyrer, Jasmine T. Plummer, Stephanie Chen, Felipe S. Dezem, Alvaro N. Barbeira, Padma S. Rajagopal, Will T. Rosenow, Fernando Moreno, Clara Bodelon, Jenny Chang-Claude, Georgia Chenevix-Trench, Anna deFazio, Thilo Dörk, Arif B. Ekici, Ailith Ewing, George Fountzilas, Ellen L. Goode, Mikael Hartman, Florian Heitz, Peter Hillemanns, Estrid Høgdall, Claus K. Høgdall, Tomasz Huzarski, Allan Jensen, Beth Y. Karlan, Elza Khusnutdinova, Lambertus A. Kiemeney, Susanne K. Kjaer, Rüdiger Klapdor, Martin Köbel, Jingmei Li, Clemens Liebrich, Taymaa May, Håkan Olsson, Jennifer B. Permuth, Paolo Peterlongo, Paolo Radice, Susan J. Ramus, Marjorie J. Riggan, Harvey A. Risch, Emmanouil Saloustros, Jacques Simard, Lukasz M. Szafron, Linda Titus, Cheryl L. Thompson, Robert A. Vierkant, Stacey J. Winham, Wei Zheng, Jennifer A. Doherty, Andrew Berchuck, Kate Lawrenson, Hae Kyung Im, Ani W. Manichaikul, Paul D.P. Pharoah, Simon A. Gayther, Joellen M. Schildkraut
Publikováno v:
HGG Advances, Vol 2, Iss 3, Pp 100042- (2021)
Summary: Familial, sequencing, and genome-wide association studies (GWASs) and genetic correlation analyses have progressively unraveled the shared or pleiotropic germline genetics of breast and ovarian cancer. In this study, we aimed to leverage thi
Externí odkaz:
https://doaj.org/article/e7f93459716f483a8f2ed03fab6135b6
Autor:
Piyush Agrawal, Navami Jain, Vishaka Gopalan, Annan Timon, Arashdeep Singh, Padma S Rajagopal, Sridhar Hannenhalli
Breast cancers exhibit substantial transcriptional heterogeneity, posing a significant challenge to the prediction of treatment response and prognostication of outcomes. Especially, translation of TNBC subtypes to the clinic remains a work in progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c41283b30cc8da53eaf894609f5e21a
https://doi.org/10.1101/2023.05.21.541618
https://doi.org/10.1101/2023.05.21.541618
Autor:
Nishanth Ulhas Nair, Kuoyuan Cheng, Lamis Naddaf, Elad Sharon, Lipika R. Pal, Padma S. Rajagopal, Irene Unterman, Kenneth Aldape, Sridhar Hannenhalli, Chi-Ping Day, Yuval Tabach, Eytan Ruppin
Publikováno v:
Science Advances. 8
Cancer is a predominant disease across animals. We applied a comparative genomics approach to systematically characterize genes whose conservation levels correlate positively (PC) or negatively (NC) with cancer resistance estimates across 193 vertebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a0478b87703e497f5ce407ba40ce96
https://doi.org/10.1126/sciadv.abj7176
https://doi.org/10.1126/sciadv.abj7176
Autor:
Gal Dinstag, Eldad D. Shulman, Efrat Elis, Doreen S. Ben-Zvi, Omer Tirosh, Eden Maimon, Isaac Meilijson, Emmanuel Elalouf, Boris Temkin, Philipp Vitkovsky, Eyal Schiff, Danh-Tai Hoang, Sanju Sinha, Nishanth Ulhas Nair, Joo Sang-Lee, Alejandro A. Schäffer, Ze'ev Ronai, Dejan Juric, Andrea B. Apolo, William L. Dahut, Stanley Lipkowitz, Raanan Berger, Razelle Kurzrock, Antonios Papanicolau-Sengos, Fatima Karzai, Mark R. Gilbert, Kenneth Aldape, Padma S. Rajagopal, Tuvik Beker, Eytan Ruppin, Ranit Aharonov
Publikováno v:
Cancer Research. 83:957-957
Background: Precision oncology is gradually advancing into mainstream clinical practice, demonstrating significant survival benefits. However, eligibility and response rates remain limited in many cases, calling for better predictive biomarkers. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4e580c6493db57d9f0838ced22807f
https://doi.org/10.1158/1538-7445.am2023-957
https://doi.org/10.1158/1538-7445.am2023-957
Autor:
Gal Dinstag, Eldad D. Shulman, Efrat Elis, Doreen S. Ben-Zvi, Omer Tirosh, Eden Maimon, Isaac Meilijson, Emmanuel Elalouf, Boris Temkin, Philipp Vitkovsky, Eyal Schiff, Danh-Tai Hoang, Sanju Sinha, Nishanth Ulhas Nair, Joo Sang Lee, Alejandro A. Schäffer, Ze’ev Ronai, Dejan Juric, Andrea B. Apolo, William L. Dahut, Stanley Lipkowitz, Raanan Berger, Razelle Kurzrock, Antonios Papanicolau-Sengos, Fatima Karzai, Mark R. Gilbert, Kenneth Aldape, Padma S. Rajagopal, Tuvik Beker, Eytan Ruppin, Ranit Aharonov
BackgroundPrecision oncology is gradually advancing into mainstream clinical practice, demonstrating significant survival benefits. However, eligibility and response rates remain limited in many cases, calling for better predictive biomarkers.Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cad0127a7138eda8c7ddea6b3390034
https://doi.org/10.1101/2022.02.27.481627
https://doi.org/10.1101/2022.02.27.481627
Autor:
Eytan Ruppin, Philip E. Castle, Padma S. Rajagopal, Nishanth Ulhas Nair, David Crawford, Ayelet Erez, Bríd M. Ryan, Alejandro A. Schäffer, Kenneth Aldape, Chi-Ping Day, Jill S. Barnholtz-Sloan, Stephen M. Mount, Sanju Sinha
Cancer occurs more frequently in men while autoimmune diseases (AIDs) occur more frequently in women. To explore whether these sex biases have a common basis, we collected 170 AID incidence studies from many countries for tissues that have both a can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c55a83817f591e4019f2e797e457cb83
https://doi.org/10.1101/2021.09.07.459207
https://doi.org/10.1101/2021.09.07.459207
Autor:
David R. Crawford, Sanju Sinha, Nishanth Ulhas Nair, Bríd M. Ryan, Jill S. Barnholtz-Sloan, Stephen M. Mount, Ayelet Erez, Kenneth Aldape, Philip E. Castle, Padma S. Rajagopal, Chi-Ping Day, Alejandro A. Schäffer, Eytan Ruppin
Publikováno v:
Cancers; Volume 14; Issue 23; Pages: 5885
Cancer occurs more frequently in men while autoimmune diseases (AIDs) occur more frequently in women. To explore whether these sex biases have a common basis, we collected 167 AID incidence studies from many countries for tissues that have both a can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fc93f68ba4cac5c9f6647ab81c124d
https://doi.org/10.3390/cancers14235885
https://doi.org/10.3390/cancers14235885
Autor:
Camilo Calvo-Alcañiz, Padma S. Rajagopal, Sanju Sinha, Fiorella Schischlik, Antonios Papanicolau-Sengos, Nishanth Ulhas Nair, Eytan Ruppin
Publikováno v:
Cancer Research. 82:985-985
Introduction: Most cancer deaths are caused by metastasis, yet understanding how metastatic cancers adapt from their origin tissues to their target tissues remains a fundamental scientific and clinical challenge. To date, no studies have systematical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9594dbf080285126186027ea4bc7538
https://doi.org/10.1158/1538-7445.am2022-985
https://doi.org/10.1158/1538-7445.am2022-985
Autor:
David Robert Crawford, Sanju Sinha, Nishanth U. Nair, Bríd M. Ryan, Jill Barnholtz-Sloan, Stephen M. Mount, Ayelet Erez, Kenneth Adalpe, Philip E. Castle, Padma S. Rajagopal, Chi-Ping Day, Alejandro A. Schäffer, Eytan Ruppin
Publikováno v:
Cancer Research. 82:27-27
Cancer occurs more frequently in men while autoimmune diseases (AIDs) occur more frequently in women. To explore whether these sex biases have a common basis, we collected 170 AID incidence studies from many countries for tissues that have both a can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75796100f519c7b3af773c83356b7082
https://doi.org/10.1158/1538-7445.am2022-27
https://doi.org/10.1158/1538-7445.am2022-27