Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Padma Nadella"'
Autor:
Robert C. Whorf, Adam Brufsky, Mauro Orlando, Michael Frontiera, Joan Kroener, Jane Bromund, John D. Hainsworth, Martin D. Marciniak, Thaddeus Beck, Fritz Tai, Mark Keaton, Timothy Panella, Padma Nadella, Devchand Paul, Coleman K. Obasaju, Luping Zhao, Karen Hoelzer, Edward Middleman, Elisa Krill-Jackson
Publikováno v:
Clinical Breast Cancer. 11:211-220
Background The addition of bevacizumab to paclitaxel improved progression-free survival (PFS) of patients with metastatic breast cancer (MBC). We examined the efficacy and safety of adding gemcitabine to paclitaxel/bevacizumab (PB). Patients and Meth
Autor:
Charles L. Shapiro, Bhuvaneswari Ramaswamy, Kari Kendra, Miguel A. Villalona-Calero, Marsha Hauger, Tim Moore, Ewa Mrozek, Padma Nadella, Chris A. Rhoades, Nancy J. Merriman, Holly Watson, Donn C. Young, Joan Allen
Publikováno v:
Clinical Breast Cancer. 7:141-145
Purpose This phase II study evaluated the safety and efficacy of weekly docetaxel and capecitabine in patients with metastatic breast cancer. Patients and Methods Thirty-nine patients with metastatic breast cancer received 30 mg/m 2 of docetaxel on d
Autor:
Rhonda Jensen, Adrian Lewis, Donn C. Young, Julie Dierksheide, Charles L. Shapiro, Padma Nadella, Cynthia M. Magro, Carrie De Hoff, Robin Parihar, Anne M. VanBuskirk, William E. Carson
Publikováno v:
Clinical Cancer Research. 10:5027-5037
Purpose: On the basis of preclinical studies, we hypothesized that interleukin (IL)12 would potentiate the antitumor actions of an antihuman epidermal growth factor receptor-2 (HER2) monoclonal antibody (trastuzumab). We conducted a Phase I trial to
Autor:
Eric H. Kraut, Steven K. Clinton, Paul Monk, Marsha Hauger, Padma Nadella, Gregory A. Otterson, Selnur Erdal, Manisha H. Shah, Mike Stanek, Miguel A. Villalona-Calero, Charles L. Shapiro
Publikováno v:
Journal of Clinical Oncology. 20:2616-2623
PURPOSE: Capecitabine and docetaxel have demonstrated preclinical antitumor synergy. This synergy is thought to occur from docetaxel-mediated upregulation of thymidine phosphorylase (dThdPase), an enzyme responsible for the relative tumor selectivity
Autor:
Michael Walker, Padma Nadella, Donn C. Young, Poongothai Sundaram, Mirela Anghelina, Gregory B. Lesinski, William E. Carson, Mario Sznol, Robin Parihar, Charles F. Eisenbeis, Jing Liu, Daniel Valentino
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(34)
PurposeTo evaluate the safety of sequentially administered recombinant (r) human (h) interleukin-12 (IL-12) and interferon alfa-2b (IFN-α-2b) in patients with advanced cancer and to determine the effects of endogenously produced IFN-γ on Janus kina
Autor:
Robin, Parihar, Padma, Nadella, Adrian, Lewis, Rhonda, Jensen, Carrie, De Hoff, Julie E, Dierksheide, Anne M, VanBuskirk, Cynthia M, Magro, Donn C, Young, Charles L, Shapiro, William E, Carson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(15)
On the basis of preclinical studies, we hypothesized that interleukin (IL)12 would potentiate the antitumor actions of an antihuman epidermal growth factor receptor-2 (HER2) monoclonal antibody (trastuzumab). We conducted a Phase I trial to determine