Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Pacman Szeto"'
Autor:
Lahiru Gangoda, Robyn L. Schenk, Lin Tai, Pacman Szeto, Jen G. Cheung, Andreas Strasser, Guillaume Lessene, Mark Shackleton, Marco J. Herold
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/fa7b8c7907f34a2890e07c751553ec89
Autor:
Ismael A. Vergara, Christopher P. Mintoff, Shahneen Sandhu, Lachlan McIntosh, Richard J. Young, Stephen Q. Wong, Andrew Colebatch, Daniel L. Cameron, Julia Lai Kwon, Rory Wolfe, Angela Peng, Jason Ellul, Xuelin Dou, Clare Fedele, Samantha Boyle, Gisela Mir Arnau, Jeanette Raleigh, Athena Hatzimihalis, Pacman Szeto, Jennifer Mooi, Daniel S. Widmer, Phil F. Cheng, Valerie Amann, Reinhard Dummer, Nicholas Hayward, James Wilmott, Richard A. Scolyer, Raymond J. Cho, David Bowtell, Heather Thorne, Kathryn Alsop, Stephen Cordner, Noel Woodford, Jodie Leditschke, Patricia O’Brien, Sarah-Jane Dawson, Grant A. McArthur, Graham J. Mann, Mitchell P. Levesque, Anthony T. Papenfuss, Mark Shackleton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genetic changes that occur in late stage metastatic melanoma are not well delineated. Here, the authors use rapid autopsy samples from metastatic melanoma patients and show that the late stage in the disease is characterised by whole genome doubl
Externí odkaz:
https://doaj.org/article/4c17fb9d0e02463397deea2b50e28d35
Autor:
Gamze Kuser-Abali, Youfang Zhang, Pacman Szeto, Peinan Zhao, Samar Masoumi-Moghaddam, Clare G. Fedele, Isobel Leece, Cheng Huang, Jen G. Cheung, Malaka Ameratunga, Fumihito Noguchi, Miles C. Andrews, Nicholas C. Wong, Ralf B. Schittenhelm, Mark Shackleton
Publikováno v:
Oncogene. 42:1360-1373
Cellular heterogeneity in cancer is linked to disease progression and therapy response, although mechanisms regulating distinct cellular states within tumors are not well understood. We identified melanin pigment content as a major source of cellular
Autor:
Mark Shackleton, Kieran F. Harvey, Anthony T. Papenfuss, Grant A. McArthur, Nicholas Hayward, Georgina V. Long, Helen Rizos, Evangeline Shaw, Katrina A. Mitchell, Lachlan McIntosh, Andrew Colebatch, Christopher Mintoff, Lie Yang, Pacman Szeto, Youfang Zhang, Ismael A. Vergara, Jian Zhong Tang, Xiaomeng Zhang
Expression of YAP, pYAP or TAZ proteins in 10 melanoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41735b01362f65a6324d78ef50ebee5e
https://doi.org/10.1158/1541-7786.22512409.v1
https://doi.org/10.1158/1541-7786.22512409.v1
Autor:
Mark Shackleton, Kieran F. Harvey, Anthony T. Papenfuss, Grant A. McArthur, Nicholas Hayward, Georgina V. Long, Helen Rizos, Evangeline Shaw, Katrina A. Mitchell, Lachlan McIntosh, Andrew Colebatch, Christopher Mintoff, Lie Yang, Pacman Szeto, Youfang Zhang, Ismael A. Vergara, Jian Zhong Tang, Xiaomeng Zhang
Melanoma is usually driven by mutations in BRAF or NRAS, which trigger hyperactivation of MAPK signaling. However, MAPK-targeted therapies are not sustainably effective in most patients. Accordingly, characterizing mechanisms that co-operatively driv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12cf2083a63aa0a263c73d0846a6dc6b
https://doi.org/10.1158/1541-7786.c.6540232.v1
https://doi.org/10.1158/1541-7786.c.6540232.v1
Autor:
Mark Shackleton, Kieran F. Harvey, Anthony T. Papenfuss, Grant A. McArthur, Nicholas Hayward, Georgina V. Long, Helen Rizos, Evangeline Shaw, Katrina A. Mitchell, Lachlan McIntosh, Andrew Colebatch, Christopher Mintoff, Lie Yang, Pacman Szeto, Youfang Zhang, Ismael A. Vergara, Jian Zhong Tang, Xiaomeng Zhang
Supplemental Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cd8174f2de9cbd20a4adbc8b1b8fc0
https://doi.org/10.1158/1541-7786.22512394.v1
https://doi.org/10.1158/1541-7786.22512394.v1
Autor:
Mark Shackleton, Anthony T. Papenfuss, Ricky W. Johnstone, Michael A. Henderson, David Gyorki, Miklos Pohl, Simon Donahoe, David Speakman, John Spillane, Robert Fuller, Annie Wong, Richard J. Young, Jeremy Lewin, Pacman Szeto, Elisha Wybacz, Vincent Corbin, Clare G. Fedele, Samantha E. Boyle
Variable re-expression patterns in PDX tumors generated from CD271- and CD271+ cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cc1f74a110271517a33ed203a32dc8
https://doi.org/10.1158/0008-5472.22406544
https://doi.org/10.1158/0008-5472.22406544
Autor:
Mark Shackleton, Anthony T. Papenfuss, Ricky W. Johnstone, Michael A. Henderson, David Gyorki, Miklos Pohl, Simon Donahoe, David Speakman, John Spillane, Robert Fuller, Annie Wong, Richard J. Young, Jeremy Lewin, Pacman Szeto, Elisha Wybacz, Vincent Corbin, Clare G. Fedele, Samantha E. Boyle
The stability of markers that identify cancer cells that propagate disease is important to the outcomes of targeted therapy strategies. In human melanoma, conflicting data exist as to whether hierarchical expression of CD271/p75/NGFR (nerve growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c890521c7089ceff883c25a0893017b1
https://doi.org/10.1158/0008-5472.c.6507099
https://doi.org/10.1158/0008-5472.c.6507099
Autor:
Mark Shackleton, Anthony T. Papenfuss, Ricky W. Johnstone, Michael A. Henderson, David Gyorki, Miklos Pohl, Simon Donahoe, David Speakman, John Spillane, Robert Fuller, Annie Wong, Richard J. Young, Jeremy Lewin, Pacman Szeto, Elisha Wybacz, Vincent Corbin, Clare G. Fedele, Samantha E. Boyle
Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8632add87e315bb9f18f8694eab907f9
https://doi.org/10.1158/0008-5472.22406532
https://doi.org/10.1158/0008-5472.22406532
Autor:
Mark Shackleton, Anthony T. Papenfuss, Ricky W. Johnstone, Michael A. Henderson, David Gyorki, Miklos Pohl, Simon Donahoe, David Speakman, John Spillane, Robert Fuller, Annie Wong, Richard J. Young, Jeremy Lewin, Pacman Szeto, Elisha Wybacz, Vincent Corbin, Clare G. Fedele, Samantha E. Boyle
Legend for Supplementary Figures S1-S8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e8374c0a745e7e0f0991d018e24d6a
https://doi.org/10.1158/0008-5472.22406562
https://doi.org/10.1158/0008-5472.22406562