Analyzing the basic principles of tissue microarray data measuring the cooperative phenomena of marker proteins in invasive breast cancer

Autor: Buerger, H, Boecker, F, Packeisen, J, Agelopoulos, K, Poos, K, Nadler, W, Korsching, E

Publikováno v: Open Access Bioinformatics, 2013, 5(1):1-21, 10.2147/OAB.S36565

The analysis of a protein-expression pattern from tissue microarray (TMA) data will not immediately give an answer on synergistic or antagonistic effects between the expression of the observed proteins. But contrary to apparent first impression, it i

Externí odkaz: http://arxiv.org/abs/1803.02287

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Interlaboratory variability of Ki67 staining in breast cancer

Autor: Focke, Cornelia M., Bürger, Horst, van Diest, Paul J., Finsterbusch, Kai, Gläser, Doreen, Korsching, Eberhard, Decker, Thomas, Anders, M., Bollmann, R., Eiting, Fr, Friedrich, K., Habeck, J. O., Haroske, G., Hinrichs, B., Behrens, A., Krause, Lars Udo, Braun-Lang, U., Lorenzen, J., Minew, N., Mlynek-Kersjes, M., Nenning, H., Packeisen, J., Poche-de Vos, F., Reyher-Klein, S., Rothacker, D., Schultz, M., Sturm, U., Tawfik, M., Berghäuser, K. H., Böcker, W, Cserni, G., Habedank, S., Lax, S., Moinfar, F., Regitnig, P., Reiner-Concin, A., Rüschoff, J., Varga, Z., Woziwodski, J., German Breast Screening Pathology Initiative

Background Postanalytic issues of Ki67 assessment in breast cancers like counting method standardisation and interrater bias have been subject of various studies, but little is known about analytic variability of Ki67 staining between pathology labs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10691::b228e4d52c5440623fee490f71d64eb7
https://dspace.library.uu.nl/handle/1874/355882

Expression of the p14ARF tumor suppressor predicts survival in acute myeloid leukemia

Autor: Carsten Müller-Tidow, Packeisen J, Th. Büchner, Arnold Ganser, K. Kügler, Horst Buerger, W.-D. Ludwig, Wolfgang E. Berdel, Achim Heinecke, Metzelder Sk, Adigüzel G, Hubert Serve, Joachim Schwäble, Gerhard Heil, Björn Steffen

Publikováno v: Leukemia. 18:720-726

Cell cycle aberrations are associated with therapy outcome in many types of cancer. We analyzed mRNA expression levels of 18 cell cycle-related genes in bone marrow samples from 78 acute myeloid leukemia (AML) patients and six controls using high-thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaf0172abe0a934598bee64a8a3229e
https://doi.org/10.1038/sj.leu.2403296

Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene

Autor: Raaphorst, F.M., Chris, J.L.M., Meijer, C.J.L.M., Fieret, E., Blokzijl, T., Mommers, E., Buerger, H., Packeisen, J., Sewalt, R.G.A.B., Otte, A.P., van Diest, P.J.

Publikováno v: Neoplasia, 5(6), 481-8. Elsevier Inc.
Raaphorst, F M, Meijer, C J L M, Fieret, E, Blokzijl, T, Mommers, E, Buerger, H, Packeisen, J, Sewalt, RA, Otte, AP & van Diest, P J 2003, ' Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene. ', Neoplasia, vol. 5, no. 6, pp. 481-8 . https://doi.org/10.1016/S1476-5586(03)80032-5
Neoplasia, 5, 481-488. Elsevier
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 6, Pp 481-488 (2003)

Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. We describe the expression of five PcG genes (BMI-1, RING1, HPC1, HPC2, and EZH2) in normal breast tissues, invasive breast carcinomas,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6646d794667e8e1d8b88dc2f7c50b0af
https://research.vumc.nl/en/publications/afcadb5c-e38d-4ebb-984a-f578879f523b