Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Pacita L. Roberts"'
Autor:
Thomas J. Hannan, Pacita L. Roberts, Terrence E. Riehl, Sjoerd van der Post, Jana M. Binkley, Drew J. Schwartz, Hiroyuki Miyoshi, Matthias Mack, Reto A. Schwendener, Thomas M. Hooton, Thaddeus S. Stappenbeck, Gunnar C. Hansson, William F. Stenson, Marco Colonna, Ann E. Stapleton, Scott J. Hultgren
Publikováno v:
EBioMedicine, Vol 1, Iss 1, Pp 46-57 (2014)
The spread of multidrug-resistant microorganisms globally has created an urgent need for novel therapeutic strategies to combat urinary tract infections (UTIs). Immunomodulatory therapy may provide benefit, as treatment of mice with dexamethasone dur
Externí odkaz:
https://doaj.org/article/06a88a77574746e8a4a2cabcd13ca808
Publikováno v:
Clin Infect Dis
Background Asymptomatic bacteriuria and pyuria in healthy women often trigger inappropriate antimicrobial treatment, but there is a paucity of data on their prevalence and persistence. Methods To evaluate the prevalence and persistence of asymptomati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e984682445002c125a1044256c48a10b
https://europepmc.org/articles/PMC8075033/
https://europepmc.org/articles/PMC8075033/
Autor:
Thomas R Hawn, Delia Scholes, Shuying S Li, Hongwei Wang, Yin Yang, Pacita L Roberts, Ann E Stapleton, Marta Janer, Alan Aderem, Walter E Stamm, Lue Ping Zhao, Thomas M Hooton
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5990 (2009)
BACKGROUND:Although behavioral risk factors are strongly associated with urinary tract infection (UTI) risk, the role of genetics in acquiring this disease is poorly understood. METHODOLOGY/PRINCIPAL FINDINGS:To test the hypothesis that polymorphisms
Externí odkaz:
https://doaj.org/article/388c628acdbd4cce9322124ad02956cb
Autor:
Pacita L. Roberts, Ann E. Stapleton, Robert K. Dinello, Thomas M. Hooton, Mark Geisberg, April N. Abbott, Marsha Cox
Publikováno v:
Journal of Clinical Microbiology. 53:2805-2809
Urinary tract infections (UTIs) are frequently encountered in clinical practice and most commonly caused by Escherichia coli and other Gram-negative uropathogens. We tested RapidBac, a rapid immunoassay for bacteriuria developed by Silver Lake Resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40327fc6671b9531b81039232932fcf
https://doi.org/10.1128/jcm.00353-15
https://doi.org/10.1128/jcm.00353-15
Autor:
Thomas J. Hannan, Wen-Chi Chou, Ashlee M. Earl, Thomas M. Hooton, Jonathan Livny, Abigail L. Manson, Michael E. Hibbing, Karen W. Dodson, Matt S. Conover, Henry L. Schreiber, Ann E. Stapleton, Scott J. Hultgren, Pacita L. Roberts
Publikováno v:
Science Translational Medicine. 9
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains. In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative genomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add906add930add084214eca0ae38631
https://doi.org/10.1126/scitranslmed.aaf1283
https://doi.org/10.1126/scitranslmed.aaf1283
Publikováno v:
Open Forum Infectious Diseases
Background Pyuria has long been considered key to diagnosis of urinary tract infection in women, but there is a paucity of data on its prevalence and association with asymptomatic bacteriuria (ASB) in healthy women, even though pyuria and ASB often t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6816fd1ff6a7bfa319f073e2e5bf0328
https://doi.org/10.1093/ofid/ofz360.1348
https://doi.org/10.1093/ofid/ofz360.1348
Autor:
Xuan Qin, Susan M. Butler-Wu, Pavel Aprikian, Angus Toland, Peggy Rogers, Kim Riddell, James R. Johnson, Ajit P. Limaye, Evgeni V. Sokurenko, Brian D. Johnston, Mariya Billig, Scott J. Weissman, Barbara C. Kahl, Irina Igusheva, Delia Scholes, Alena Gileva, Elena V. Linardopoulou, Pacita L. Roberts, Brad T. Cookson, Sujay Chattopadhyay, Ferric C. Fang, Veronika Skrivankova, Veronika Tchesnokova, Lance B. Price
Publikováno v:
Journal of Clinical Microbiology. 51:2991-2999
The ability to identify bacterial pathogens at the subspecies level in clinical diagnostics is currently limited. We investigated whether splitting Escherichia coli species into clonal groups (clonotypes) predicts antimicrobial susceptibility or clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624f215de9768c10311136da534b82fd
https://doi.org/10.1128/jcm.00984-13
https://doi.org/10.1128/jcm.00984-13
Autor:
Henry L, Schreiber, Matt S, Conover, Wen-Chi, Chou, Michael E, Hibbing, Abigail L, Manson, Karen W, Dodson, Thomas J, Hannan, Pacita L, Roberts, Ann E, Stapleton, Thomas M, Hooton, Jonathan, Livny, Ashlee M, Earl, Scott J, Hultgren
Publikováno v:
Science translational medicine. 9(382)
Urinary tract infections (UTIs) are caused by uropathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47519ae379e99804f3d0539466ca820b
https://pubmed.ncbi.nlm.nih.gov/29783597
https://pubmed.ncbi.nlm.nih.gov/29783597
Autor:
Thomas M. Hooton, Christopher A. Czaja, Walter E. Stamm, Yuliya Yarova-Yarovaya, David N. Fredricks, Melissa Au-Yeung, Ann E. Stapleton, Pacita L. Roberts, Marsha Cox, Tina L. Fiedler
Publikováno v:
Clinical Infectious Diseases. 52:1212-1217
Background. Urinary tract infections (UTIs) are common among women and frequently recur. Depletion of vaginal lactobacilli is associated with UTI risk, which suggests that repletion may be beneficial. We conducted a double-blind placebo-controlled tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b3d5a87c76bdbcae9498d37d2c7767
https://doi.org/10.1093/cid/cir183
https://doi.org/10.1093/cid/cir183
Autor:
Aurelio Silvestroni, Ann E. Stapleton, Thomas M. Hooton, Samuel I. Miller, Mitchell J. Brittnacher, Pacita L. Roberts, Marsha Cox, Hillary S. Hayden
Publikováno v:
Open Forum Infectious Diseases
Background We investigated vaginal colonization using repetitive sequence PCR (repPCR) and 16S rRNA sequencing in a Phase 2b DBPC trial of a L. crispatus intravaginal suppository probiotic for prevention of rUTI in premenopausal women. Methods Twenty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083b7b7b50655b04733cb6a35123cc55
http://europepmc.org/articles/PMC6252922
http://europepmc.org/articles/PMC6252922