A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.

Autor: Paciaroni, Nicholas G.^1,2, Ratnayake, Ranjala^1,2, Matthews, James H.^1,2, Norwood, Verrill M.^1,2, Arnold, Austin C.¹, Dang, Long H.^1,2,3, Luesch, Hendrik^1,2, Huigens, Robert W.^1,2 rhuigens@cop.ufl.edu

Publikováno v: Chemistry - A European Journal. 3/28/2017, Vol. 23 Issue 18, p4327-4335. 9p.

Microwave-enhanced, stereospecific ring-closure of medium-ring cyanamide ethers to yohimbine

Autor: Paciaroni, Nicholas G., Norwood, Verrill M., IV, Garcia, Daniel E., Huigens, Robert W., III

Publikováno v: In Tetrahedron Letters 25 April 2019 60(17):1182-1185

Beyond protein binding: recent advances in screening DNA-encoded libraries.

Autor: Kodadek, Thomas, Paciaroni, Nicholas G., Balzarini, Madeline, Dickson, Paige

Publikováno v: Chemical Communications; 11/18/2019, Vol. 55 Issue 89, p13330-13341, 12p

Back Cover: A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine (Chem. Eur. J. 18/2017).

Autor: Paciaroni, Nicholas G.^1,2, Ratnayake, Ranjala^1,2, Matthews, James H.^1,2, Norwood, Verrill M.^1,2, Arnold, Austin C.¹, Dang, Long H.^1,2,3, Luesch, Hendrik^1,2, Huigens, Robert W.^1,2 rhuigens@cop.ufl.edu

Publikováno v: Chemistry - A European Journal. 3/28/2017, Vol. 23 Issue 18, p4463-4463. 1p.

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.

Autor: Guijarro MV; Department of Anatomy and Cell Biology., Kellish PC; Department of Anatomy and Cell Biology., Dib PE; Department of Anatomy and Cell Biology., Paciaroni NG; Department of Medicinal Chemistry, and., Nawab A; Department of Anatomy and Cell Biology., Andring J; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA., Kulemina L; Department of Anatomy and Cell Biology., Borrero NV; Department of Medicinal Chemistry, and., Modenutti C; Department of Biological Chemistry, Faculty of Exact and Natural Sciences, University of Buenos Aires, and.; Institute of Biological Chemistry of the Faculty of Exact and Natural Sciences (IQUIBICEN) CONICET, University City, Pab. II (CE1428EHA), Buenos Aires, Argentina., Feely M; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA., Nasri E; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA., Seifert RP; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA., Luo X; Department of Anatomy and Cell Biology., Bennett RL; Department of Medicine, University of Florida Health Cancer Center, Gainesville, Florida, USA., Shabashvili D; Department of Anatomy and Cell Biology., Licht JD; Department of Medicine, University of Florida Health Cancer Center, Gainesville, Florida, USA., McKenna R; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA., Roitberg A; Department of Chemistry, University of Florida, Gainesville, Florida, USA., Huigens RW 3rd; Department of Medicinal Chemistry, and., Kaye FJ; Department of Medicine, University of Florida Health Cancer Center, Gainesville, Florida, USA., Zajac-Kaye M; Department of Anatomy and Cell Biology.; Department of Medicine, University of Florida Health Cancer Center, Gainesville, Florida, USA.

Publikováno v: JCI insight [JCI Insight] 2023 Apr 25; Vol. 8 (10). Date of Electronic Publication: 2023 Apr 25.