Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Pachiappan Manickam"'
Autor:
Kehler, James, Greco, Marianna, Martino, Valentina, Pachiappan, Manickam, Yokoe, Hiroko, Chen, Alice, Yang, Miranda, Auerbach, Jonathan, Jessee, Joel, Gotte, Martin, Milanesi, Luciano, Albertini, Alberto, Bellipanni, Gianfranco, Zucchi, Ileana, Reinbold, Rolland A, Giordano, Antonio
Publikováno v:
Journal of cellular physiology
(2016). doi:10.1002/jcp.25597
info:cnr-pdr/source/autori:Kehler, James; Greco, Marianna; Martino, Valentina; Pachiappan, Manickam; Yokoe, Hiroko; Chen, Alice; Yang, Miranda; Auerbach, Jonathan; Jessee, Joel; Gotte, Martin; Milanesi, Luciano; Albertini, Alberto; Bellipanni, Gianfranco; Zucchi, Ileana; Reinbold, Rolland A; Giordano, Antonio/titolo:RNA-Generated and Gene-Edited Induced Pluripotent Stem Cells for Disease Modeling and Therapy./doi:10.1002%2Fjcp.25597/rivista:Journal of cellular physiology (Print)/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume
(2016). doi:10.1002/jcp.25597
info:cnr-pdr/source/autori:Kehler, James; Greco, Marianna; Martino, Valentina; Pachiappan, Manickam; Yokoe, Hiroko; Chen, Alice; Yang, Miranda; Auerbach, Jonathan; Jessee, Joel; Gotte, Martin; Milanesi, Luciano; Albertini, Alberto; Bellipanni, Gianfranco; Zucchi, Ileana; Reinbold, Rolland A; Giordano, Antonio/titolo:RNA-Generated and Gene-Edited Induced Pluripotent Stem Cells for Disease Modeling and Therapy./doi:10.1002%2Fjcp.25597/rivista:Journal of cellular physiology (Print)/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume
Cellular reprogramming by epigenomic remodeling of chromatin holds great promise in the field of human regenerative medicine. As an example, human-induced Pluripotent Stem Cells (iPSCs) obtained by reprograming of patient somatic cells are sufficient
Autor:
Peethambaran Arun, Toshitaka Nabeshima, Prasanth S. Ariyannur, John R. Moffett, Nagarajan Pattabiraman, Atsumi Nitta, Pachiappan Manickam, Chikkathur N. Madhavarao, Aryan M.A. Namboodiri
Publikováno v:
Brain Research. 1335:1-13
N-acetylaspartate (NAA) is a concentrated, neuron-specific brain metabolite routinely used as a magnetic resonance spectroscopy marker for brain injury and disease. Despite decades of research, the functional roles of NAA remain unclear. Biochemical
Autor:
David J. Handelsman, Pachiappan Manickam, Da-Wei Gong, Jas Singh, Gareth Denyer, Michael Shmoish, Sara Natik, Qihan Dong
Publikováno v:
Cancer Letters. 237:298-304
In silico methods and array technologies have identified genes differentially expressed in prostate cancer. Biological functions of the identified genes are often unclear. Considering the biological significance of androgens in prostate cancer, we pr
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Publikováno v:
Infection and Immunity. 73:4381-4384
Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of theAspergillusallergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA. Of the 12,000 genes studied, 1,300 genes showe
Autor:
Takaya Oda, Settara C. Chandrasekharappa, Brant M. Weinstein, Pachiappan Manickam, Andreas M. Vogel, Allen M. Spiegel, Francis S. Collins, Sunita K. Agarwal, Stephen J. Marx
Publikováno v:
Mammalian Genome. 11:448-454
Mutations in the MEN1 gene lead to an autosomal dominant disorder, multiple endocrine neoplasia type 1 (MEN1), which is characterized by tumors of the parathyroid, entero-pancreatic neuroendocrine, and pituitary tissues. The protein encoded by MEN1,
Autor:
Elisabeth Brambilla, Sunita K. Agarwal, Stephen J. Marx, Galina Baibakov, Michael R. Emmert-Buck, William D. Travis, Michael J. Kelley, Francis S. Collins, Allen M. Spiegel, Settara C. Chandrasekharappa, Pachiappan Manickam, Larisa V. Debelenko, Jennifer I. Swalwell
Publikováno v:
Genes, Chromosomes and Cancer. 28:58-65
Neuroendocrine tumors of the lung consist of a spectrum of neoplasms, including typical carcinoids, atypical carcinoids, large-cell neuroendocrine carcinomas (LCNEC), and small-cell lung carcinomas (SCLC). We previously reported frequent inactivation
Autor:
Settara C. Chandrasekharappa, J. Leslie Redpath, C. Sun, Eric J. Stanbridge, Ulla Bengtsson, Eri S. Srivatsan, Payam Benyamini, Pachiappan Manickam
Publikováno v:
Genes, Chromosomes and Cancer. 29:157-165
Previous cytogenetic and molecular genetic studies have shown that the HeLa (cervical carcinoma) cell line D98/AH-2 contains two apparently normal copies of chromosome 11 and additional 11q13-25 material translocated onto a chromosome 3 marker. To de
Autor:
R. H. Alexander, Allen M. Spiegel, Michael R. Emmert-Buck, Lance A. Liotta, J L Doppman, Irina A. Lubensky, Siradanahalli C. Guru, A L Burns, Larisa V. Debelenko, S E Olufemi, Christina Heppner, Young Sik Kim, Mary Beth Kester, Sunita K. Agarwal, Stephen J. Marx, Z. Zhuang, Settara C. Chandrasekharappa, Monica C. Skarulis, Pachiappan Manickam, Frank H. Collins
Publikováno v:
Journal of Internal Medicine. 243:447-453
Dideoxyfingerprinting was used to screen for germline and somatic MEN1 mutations. This method, applied to a panel of germline DNA from 15 probands with multiple endocrine neoplasia type 1 (MEN-1), allowed confident discovery of the MEN1 gene. Germlin
Autor:
Shodimu Emmanuel Olufemi, Allen M. Spiegel, Francis S. Collins, Sunita K. Agarwal, Settara C. Chandrasekharappa, Stephen J. Marx, A. Lee Burns, Jane Green, Qihan Dong, Siradanahalli C. Guru, Mary Beth Kester, Pachiappan Manickam
Publikováno v:
Human Mutation. 11:264-269
Familial multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder with affected individuals developing parathyroid, gastrointestinal (GI) endocrine, and anterior pituitary tumors. Four large kindreds from the Burin peninsula/Fortu