Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer: A Randomized Clinical Trial.

Autor: Takahashi N; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland.; National Cancer Center Hospital East, Kashiwa, Japan., Hao Z; Division of Medical Oncology, University of Kentucky College of Medicine, Lexington., Villaruz LC; Division of Hematology/Oncology, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, Pennsylvania., Zhang J; Division of Medical Oncology, University of Kansas Medical Center, Kansas City, Kansas., Ruiz J; Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, North Carolina., Petty WJ; Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, North Carolina., Mamdani H; Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan., Riess JW; UC Davis Comprehensive Cancer Center, Sacramento, California., Nieva J; Norris Cancer Center, University of Southern California, Los Angeles., Pachecho JM; University of Colorado Cancer Center, Aurora., Fuld AD; Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Shum E; Laura and Isaac Perlmutter Cancer Center, New York, New York., Chauhan A; Division of Medical Oncology, University of Kentucky College of Medicine, Lexington., Nichols S; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Shimellis H; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., McGlone J; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Sciuto L; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Pinkiert D; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Graham C; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Shelat M; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Kattappuram R; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Abel M; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Schroeder B; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Upadhyay D; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Krishnamurthy M; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Sharma AK; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Kumar R; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Malin J; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Schultz CW; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Goyal S; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Redon CE; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Pommier Y; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Aladjem MI; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Gore SD; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Steinberg SM; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Vilimas R; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Desai P; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland., Thomas A; National Cancer Institute, Center for Cancer Research, Bethesda, Maryland.

Publikováno v: JAMA oncology [JAMA Oncol] 2023 Dec 01; Vol. 9 (12), pp. 1669-1677.