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Tailoring enhanced production and identification of isoflavones in the callus cultures of Pueraria thomsonii Benth and its model verification using response surface methodology (RSM): a combined in vitro and statistical optimization

Autor: Yu Li, Pachaiyappan Saravana Kumar, Yu Liu, Jiao Qiu, Yalan Ran, Mingyuan Yuan, Xinyue Fang, Xuhui Tan, Renjun Zhao, Ji zhu, Meijun He

Publikováno v: Beni-Suef University Journal of Basic and Applied Sciences, Vol 11, Iss 1, Pp 1-13 (2022)

Abstract Background Scientifically, isoflavones from Pueraria thomsonii Benth possess diverse pharmacological activities and have been used to treat various diseases. In vitro propagation of callus has contributed to the reliability for large-scale p

Externí odkaz: https://doaj.org/article/b552e818f2a24bff8cb0d60ce8db1e18

Diversity and chemical fingerprinting of endo-metabolomes from endophytes associated with Ampelopsis grossedentata (Hand.-Mazz.) W. T. Wang possessing antibacterial activity against multidrug resistant bacterial pathogens

Autor: Yu Li, Pachaiyappan Saravana Kumar, Quansheng Tan, Xuhui Tan, Mingyuan Yuan, Jianqiong Luo, Meijun He

Publikováno v: Journal of Infection and Public Health, Vol 14, Iss 12, Pp 1917-1926 (2021)

Background: Serious infections caused by bacteria and their resistance to antibiotics are one of the biggest healthcare threats to mankind. Therefore, the present study aimed to isolate endophytes from medicinal plant Ampelopsis grossedentata, an end

Externí odkaz: https://doaj.org/article/dfe2a7f9721148e09554d1ab2efd7334

Genome Sequencing of Streptomyces griseus SCSIO PteL053, the Producer of 2,2′-Bipyridine and Actinomycin Analogs, and Associated Biosynthetic Gene Cluster Analysis

Autor: Ganesan Govindarajan, Ziwei Yao, Zhenbin Zhou, Xiaohong Zheng, Junying Ma, Pachaiyappan Saravana Kumar, Jianhua Ju, Changli Sun

Publikováno v: Journal of Marine Science and Engineering, Vol 11, Iss 2, p 396 (2023)

Marine symbiotic actinomycetes play a key role in drug development and their ecological niches can influence a variety of natural product biosynthesis, providing potential defensive benefits. In this study, we report the whole-genome sequence analysi

Externí odkaz: https://doaj.org/article/d90fe5069e224818b2b03a9fd92061fe

Antibacterial Activity study of Musizin isolated from Rhamnus wightii Wight and Arn.

Autor: Tharsius Raja WR; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai., Antony S; 2Division of Bioinformatics,Entomology Research Institute, Loyola College, Chennai.; Centre of Advanced Studies in Botany and Centre for Herbal Sciences,University of Madras, Guindy Campus, Chennai 600 025, India., Pachaiyappan S; Division of Microbiology, Entomology Research Institute, LoyolaCollege, Chennai - Chennai., Amalraj J; Division of Microbiology, Entomology Research Institute, LoyolaCollege, Chennai - Chennai., Narasimhan P; Centre of Advanced Studies in Botany and Centre for Herbal Sciences,University of Madras, Guindy Campus, Chennai 600 025, India., Keduki B; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai., Veeramuthu D; Division of Microbiology, Entomology Research Institute, LoyolaCollege, Chennai - Chennai.; Department of Botany and Microbiology, Addiriyah Chair for Environmental Studies Collegeof Science, King Saud University, Riyadh 11451, Saudi Arabia., Perumal P; Centre of Advanced Studies in Botany and Centre for Herbal Sciences,University of Madras, Guindy Campus, Chennai 600 025, India., Savarimuthu I; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai.; International Scientific Partnership Program, King Saud University, PostBox 2455, Riyadh 1011 11451, Kingdom of Saudi Arabia.

Publikováno v: Bioinformation [Bioinformation] 2018 Dec 21; Vol. 14 (9), pp. 511-520. Date of Electronic Publication: 2018 Dec 21 (Print Publication: 2018).