Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Pablo Sobrado"'
Autor:
Keane J. Dye, Nancy J. Vogelaar, Megan O’Hara, Pablo Sobrado, Webster Santos, Paul R. Carlier, Zhaomin Yang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT With the pressing antibiotic resistance pandemic, antivirulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive
Externí odkaz:
https://doaj.org/article/4c05d73fe5684cdb8db1f193e97bcb71
Autor:
Hannah Valentino, David A. Korasick, Tabbetha J. Bohac, Justin A. Shapiro, Timothy A. Wencewicz, John J. Tanner, Pablo Sobrado
Publikováno v:
ACS Omega, Vol 6, Iss 28, Pp 18537-18547 (2021)
Externí odkaz:
https://doaj.org/article/43a20f12ab4e4abea5c5c7c513e7d5df
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
Many bacterial pathogens use their type IV pili (T4P) to facilitate and maintain infection of a human host. Small chemical compounds that inhibit the production or assembly of T4P have promise in the treatment and prevention of infections, especially
Externí odkaz:
https://doaj.org/article/4cb177181c3544439641c6b5decdb39a
Autor:
Benjamin A. Webb, K. Karl Compton, Julia S. Martin del Campo, Doris Taylor, Pablo Sobrado, Birgit E. Scharf
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 30, Iss 10, Pp 770-777 (2017)
The legume symbiont Sinorhizobium meliloti is chemoattracted to compounds exuded by germinating seeds of its host alfalfa. This response is mainly mediated by the S. meliloti chemoreceptor McpU. McpU also has a prominent contribution in sensing a syn
Externí odkaz:
https://doaj.org/article/1e16725fbe204b6c88eeb99dee6d6355
Autor:
Heba Abdelwahab, Julia S Martin Del Campo, Yumin Dai, Camelia Adly, Sohby El-Sohaimy, Pablo Sobrado
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0162578 (2016)
A novel mechanism of rifampicin (Rif) resistance has recently been reported in Nocardia farcinica. This new mechanism involves the activity of rifampicin monooxygenase (RifMO), a flavin-dependent monooxygenase that catalyzes the hydroxylation of Rif,
Externí odkaz:
https://doaj.org/article/b0a4509e78204c20a6a3fbbb821676da
Autor:
Kendra Bufkin, Pablo Sobrado
Publikováno v:
Molecules, Vol 22, Iss 10, p 1652 (2017)
N-Hydroxylating monooxygenases (NMOs) are involved in siderophore biosynthesis. Siderophores are high affinity iron chelators composed of catechol and hydroxamate functional groups that are synthesized and secreted by microorganisms and plants. Recen
Externí odkaz:
https://doaj.org/article/0c35d0925667416fa36289dad64583a7
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32918 (2012)
UDP-galactopyranose mutase (UGM) is a flavoenzyme that catalyzes the conversion of UDP-galactopyranose to UDP-galactofuranose, the precursor of galactofuranose (Galf). Galf is found in several pathogenic organisms, including the parasite Trypanosoma
Externí odkaz:
https://doaj.org/article/6ed5401f6de747da94f074b23c1956d7
Autor:
Hannah Valentino, Pablo Sobrado
Publikováno v:
Biochemistry. 60:2851-2864
N-hydroxylating monooxygenases (NMOs) are a subclass of flavin-dependent enzymes that hydroxylate nitrogen atoms. Recently, unique NMOs that perform multiple reactions on one substrate molecule have been identified. Fosfazinomycin M (FzmM) is one suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741929ac84dc917a312626eedb0396c7
https://doi.org/10.1021/acs.biochem.1c00512
https://doi.org/10.1021/acs.biochem.1c00512
Acinetobacter baumannii is a Gram-negative opportunistic pathogen that causes nosocomial infections, especially among immunocompromised individuals. The rise of multidrug resistant strains of A. baumannii has limited the use of standard antibiotics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ce33ebad2239afb7eb07809f9532ad
https://hdl.handle.net/10919/113361
https://hdl.handle.net/10919/113361
Publikováno v:
Biochemistry. 61(22)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::498e0644d86a030048d0a914ac6008c8
https://pubmed.ncbi.nlm.nih.gov/36314559
https://pubmed.ncbi.nlm.nih.gov/36314559