Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Pablo Sobrado"'
Autor:
Keane J. Dye, Nancy J. Vogelaar, Megan O’Hara, Pablo Sobrado, Webster Santos, Paul R. Carlier, Zhaomin Yang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT With the pressing antibiotic resistance pandemic, antivirulence has been increasingly explored as an alternative strategy against bacterial infections. The bacterial type IV pilus (T4P) is a well-documented virulence factor and an attractive
Externí odkaz:
https://doaj.org/article/4c05d73fe5684cdb8db1f193e97bcb71
Autor:
Hannah Valentino, David A. Korasick, Tabbetha J. Bohac, Justin A. Shapiro, Timothy A. Wencewicz, John J. Tanner, Pablo Sobrado
Publikováno v:
ACS Omega, Vol 6, Iss 28, Pp 18537-18547 (2021)
Externí odkaz:
https://doaj.org/article/43a20f12ab4e4abea5c5c7c513e7d5df
Publikováno v:
mSphere, Vol 6, Iss 2 (2021)
Many bacterial pathogens use their type IV pili (T4P) to facilitate and maintain infection of a human host. Small chemical compounds that inhibit the production or assembly of T4P have promise in the treatment and prevention of infections, especially
Externí odkaz:
https://doaj.org/article/4cb177181c3544439641c6b5decdb39a
Autor:
Benjamin A. Webb, K. Karl Compton, Julia S. Martin del Campo, Doris Taylor, Pablo Sobrado, Birgit E. Scharf
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 30, Iss 10, Pp 770-777 (2017)
The legume symbiont Sinorhizobium meliloti is chemoattracted to compounds exuded by germinating seeds of its host alfalfa. This response is mainly mediated by the S. meliloti chemoreceptor McpU. McpU also has a prominent contribution in sensing a syn
Externí odkaz:
https://doaj.org/article/1e16725fbe204b6c88eeb99dee6d6355
Autor:
Hannah Valentino, Pablo Sobrado
Publikováno v:
Biochemistry. 60:2851-2864
N-hydroxylating monooxygenases (NMOs) are a subclass of flavin-dependent enzymes that hydroxylate nitrogen atoms. Recently, unique NMOs that perform multiple reactions on one substrate molecule have been identified. Fosfazinomycin M (FzmM) is one suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741929ac84dc917a312626eedb0396c7
https://doi.org/10.1021/acs.biochem.1c00512
https://doi.org/10.1021/acs.biochem.1c00512
Acinetobacter baumannii is a Gram-negative opportunistic pathogen that causes nosocomial infections, especially among immunocompromised individuals. The rise of multidrug resistant strains of A. baumannii has limited the use of standard antibiotics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ce33ebad2239afb7eb07809f9532ad
https://hdl.handle.net/10919/113361
https://hdl.handle.net/10919/113361
Publikováno v:
Biochemistry. 61(22)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::498e0644d86a030048d0a914ac6008c8
https://pubmed.ncbi.nlm.nih.gov/36314559
https://pubmed.ncbi.nlm.nih.gov/36314559
Autor:
Pablo Sobrado, José Luis Neira
Publikováno v:
Archives of Biochemistry and Biophysics. 742:109635
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae9ae12afc8e9aa45e0876248e112a4
https://doi.org/10.1016/j.abb.2023.109635
https://doi.org/10.1016/j.abb.2023.109635
Autor:
John J. Tanner, Justin A. Shapiro, Timothy A. Wencewicz, David A. Korasick, Hannah Valentino, Tabbetha J Bohac, Pablo Sobrado
Publikováno v:
ACS Omega, Vol 6, Iss 28, Pp 18537-18547 (2021)
ACS Omega
ACS Omega
Acinetobacter baumannii is an opportunistic pathogen with a high mortality rate due to multi-drug-resistant strains. The synthesis and uptake of the iron-chelating siderophores acinetobactin (Acb) and preacinetobactin (pre-Acb) have been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60aceee810ddbf19f3343c63c1719f45
https://doaj.org/article/43a20f12ab4e4abea5c5c7c513e7d5df
https://doaj.org/article/43a20f12ab4e4abea5c5c7c513e7d5df
Autor:
Hao Li, Meital Eckshtain-Levi, John J. Tanner, Pablo Sobrado, Julia S. Martin del Campo, Hannah Valentino, Benedicta Forson
Publikováno v:
Biochemistry. 60:31-40
The flavin reductase (FRED) and isobutylamine N-hydroxylase (IBAH) from Streptomyces viridifaciens constitute a two-component, flavin-dependent monooxygenase system that catalyzes the first step in valanimycin biosynthesis. FRED is an oxidoreductase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8b318daa57858d4216356da159ea53
https://doi.org/10.1021/acs.biochem.0c00679
https://doi.org/10.1021/acs.biochem.0c00679