Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pablo Saenz-Lopez"'
Autor:
Anthony V. Serritella, Pablo Saenz-Lopez Larrocha, Payal Dhar, Sizhe Liu, Milan M. Medd, Shengxian Jia, Qi Cao, Jennifer D. Wu
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 196 (2024)
NKG2D is an activating receptor expressed by all human NK cells and CD8 T cells. Harnessing the NKG2D/NKG2D ligand axis has emerged as a viable avenue for cancer immunotherapy. However, there is a long-standing controversy over whether soluble NKG2D
Externí odkaz:
https://doaj.org/article/c9111402da72415097efdb40a0bfedd3
Autor:
Jinyu Zhang, Pablo Saenz-lopez Larrocha, Bin Zhang, Derek Wainwright, Payal Dhar, Jennifer D. Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background Insufficient co-stimulation accounts for a great deal of the suboptimal activation of cytotoxic CD8 T cells (CTLs) and presumably unsatisfactory clinical expectation of PD1/PD-L1 therapy. Tumor-derived soluble NKG2D ligands are as
Externí odkaz:
https://doaj.org/article/87a84d4e39904cee95a00e1d5ff9564f
Autor:
John C. Tran, Thomas Hunsaker, Christina Bell, Taylur P. Ma, Emily Chan, Pablo Saenz-Lopez Larrocha, Kelsey Homyk, Liling Liu, Hank La, Jialin Mao, Cecile C. de la Cruz, Kebing Yu, Maureen Beresini, William F. Forrest, Yang Xiao, Anne Jang, Natalia Samus, Nicholas Dupuis Stesco, Marija Mentinova, Stephane Parent, Gwenael Pottiez, Michael Schirm, Hans E. Purkey, Yichin Liu, Mark Merchant
Publikováno v:
Analytical Chemistry. 95:4834-4839
Autor:
Hadir Marei, Wen-Ting K. Tsai, Yee-Seir Kee, Karen Ruiz, Jieyan He, Chris Cox, Tao Sun, Sai Penikalapati, Pankaj Dwivedi, Meena Choi, David Kan, Pablo Saenz-Lopez, Kristel Dorighi, Pamela Zhang, Yvonne T. Kschonsak, Noelyn Kljavin, Dhara Amin, Ingrid Kim, Andrew G. Mancini, Thao Nguyen, Chunling Wang, Eric Janezic, Alexander Doan, Elaine Mai, Hongkang Xi, Chen Gu, Melanie Heinlein, Brian Biehs, Jia Wu, Isabelle Lehoux, Seth Harris, Laetitia Comps-Agrar, Dhaya Seshasayee, Frederic J. de Sauvage, Matthew Grimmer, Jing Li, Nicholas J. Agard, Felipe de Sousa e Melo
Publikováno v:
Nature. 610:182-189
Most current therapies that target plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. However, typical mammalian proteins comprise multiple domains that execute discrete but coordinated activities. Thus, inhibi
Akademický článek
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Akademický článek
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Autor:
Jinyu Zhang, Larrocha, Pablo Saenz-lopez, Bin Zhang, Wainwright, Derek, Dhar, Payal, Wu, Jennifer D.
Publikováno v:
Journal for ImmunoTherapy of Cancer; 12/1/2019, Vol. 7 Issue 1, p1-15, 15p
Akademický článek
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Autor:
Irene Gazquez, Antonia Ruiz Moreno, Andrés Soto-Varela, Sofia Santos, Carlos Gonzalez-Oller, Águeda Ibañez, Ismael Aran, Miguel A. López-Nevot, Jose A. Lopez-Escamez, Herminio Pérez-Garrigues, Pablo Saenz-Lopez
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 12, Iss 1, p 2 (2011)
BMC Medical Genetics, Vol 12, Iss 1, p 2 (2011)
This study was supported by a research project FIS PI07/0035. JALE was partially supported by ISCIII research grant INT09/229. The 3130 XL Genetics Analyzer was funded by grant IF06/37291 from Ministry of Science. BACKGROUND: Autoimmune diseases with
Autor:
Jose A, Lopez-Escamez, Pablo, Saenz-Lopez, Lourdes, Acosta, Antonia, Moreno, Irene, Gazquez, Herminio, Perez-Garrigues, Alicia, Lopez-Nevot, Miguel A, Lopez-Nevot
Publikováno v:
The Laryngoscope. 120(1)
Bilateral Meniere's disease (BMD) is a severe disease that usually results in bilateral severe or profound sensorineural hearing loss and chronic disequilibrium with loss of vestibular function. We examined single nucleotide polymorphisms (SNPs) in t