Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Pablo R, Moya"'
Autor:
Bastián I. Cortés, Rodrigo C. Meza, Carlos Ancatén-González, Nicolás M. Ardiles, María-Ignacia Aránguiz, Hideaki Tomita, David R. Kaplan, Francisca Cornejo, Alexia Nunez-Parra, Pablo R. Moya, Andrés E. Chávez, Gonzalo I. Cancino
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-15 (2024)
Abstract Background The brain cortex is responsible for many higher-level cognitive functions. Disruptions during cortical development have long-lasting consequences on brain function and are associated with the etiology of brain disorders. We previo
Externí odkaz:
https://doaj.org/article/d4a3502f9ed749f19ffeddc6183b865b
Autor:
Ramón Pérez-Núñez, Alejandro Chamorro, María Fernanda González, Pamela Contreras, Rocío Artigas, Alejandro H. Corvalán, Brigitte van Zundert, Christopher Reyes, Pablo R. Moya, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can
Externí odkaz:
https://doaj.org/article/8f88a252b77145c0982c107e62d40b7f
Autor:
Ulises Ríos, Javier Morán, Jimena Hermosilla, René González, Paulina Muñoz, Marcelo Arancibia, Luisa Herrera, Juan Pablo Jiménez, Pablo R. Moya
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundMost studies on cognitive impairment in bipolar disorder have neglected the role of early stress, despite the high frequency of childhood maltreatment in this clinical group. The aim of this study was to establish a connection between a his
Externí odkaz:
https://doaj.org/article/b1d9eff4bab74f76af68739571764c25
Autor:
Angélica P. Escobar, Jonathan Martínez-Pinto, Francisco Silva-Olivares, Ramón Sotomayor-Zárate, Pablo R. Moya
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The excitatory amino acid transporter EAAT3 plays an important role in the neuronal uptake of glutamate regulating the activation of glutamate receptors. Polymorphisms in the gene-encoding EAAT3 have been associated with obsessive–compulsive disord
Externí odkaz:
https://doaj.org/article/dfef4f7f58b4450aae4f340786ed52f2
Autor:
Luis F. González, Francisca Henríquez-Belmar, Claudia Delgado-Acevedo, Marisol Cisternas-Olmedo, Gloria Arriagada, Ramón Sotomayor-Zárate, Dennis L. Murphy, Pablo R. Moya
Publikováno v:
Biological Research, Vol 50, Iss 1, Pp 1-9 (2017)
Abstract Background Obsessive–compulsive disorder (OCD) is a severe neuropsychiatric condition affecting 1–3% of the worldwide population. OCD has a strong genetic component, and the SLC1A1 gene that encodes neuronal glutamate transporter EAAT3 i
Externí odkaz:
https://doaj.org/article/018f77851ef04a269b1903f900fac86d
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Obsessive compulsive disorder (OCD) is a heterogeneous psychiatric disorder affecting 1%–3% of the population worldwide. About half of OCD afflicted individuals do not respond to currently available pharmacotherapy, which is mainly based on seroton
Externí odkaz:
https://doaj.org/article/c61cb208d3b74b2483ca628aad433bf4
Autor:
Miguel Ángel Pérez, Camila Morales, Odra Santander, Francisca García, Isabel Gómez, Valentín Peñaloza-Sancho, Pablo Fuentealba, Alexies Dagnino-Subiabre, Pablo R. Moya, Marco Fuenzalida
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Schizophrenia (SZ) is associated with changes in the structure and function of several brain areas. Several findings suggest that these impairments are related to a dysfunction in γ-aminobutyric acid (GABA) neurotransmission in brain areas such as t
Externí odkaz:
https://doaj.org/article/239005d8197d42ec83e796f39b6f1259
Autor:
Alvaro Cavieres, Carolina Campos-Estrada, Yanneth Moya, Rocío Maldonado, René González-Vargas, María Leonor Bustamante, Pablo R. Moya
Publikováno v:
Schizophrenia Research and Treatment, Vol 2019 (2019)
Alterations in neuroinflammatory processes have been suggested to contribute to the development of Schizophrenia (SZ); one component of the inflammatory system that has been linked to this disorder is interleukin-6 (IL-6). The minor allele of rs22281
Externí odkaz:
https://doaj.org/article/771f2d538bdb41bf853ba540b9087596
Autor:
Pablo R. Moya, Niels Hellings, Tim Vanmierlo, Assia Tiane, Lieve van Veggel, Jack van Horssen, David M. Wilson, Melissa Schepers, Bert O. Eijnde, Elisabeth Piccart, Wim Derave, Jan H. Spaas, Rudy Schreiber
Publikováno v:
Cellular and Molecular Life Sciences
Spaas, J, van Veggel, L, Schepers, M, Tiane, A, van Horssen, J, Wilson, D M, Moya, P R, Piccart, E, Hellings, N, Eijnde, B O, Derave, W, Schreiber, R & Vanmierlo, T 2021, ' Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders ', Cellular and Molecular Life Sciences, vol. 78, no. 10, pp. 4615-4637 . https://doi.org/10.1007/s00018-021-03802-0
CELLULAR AND MOLECULAR LIFE SCIENCES
Spaas, J, van Veggel, L, Schepers, M, Tiane, A, van Horssen, J, Wilson, D M, Moya, P R, Piccart, E, Hellings, N, Eijnde, B O, Derave, W, Schreiber, R & Vanmierlo, T 2021, ' Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders ', Cellular and Molecular Life Sciences, vol. 78, no. 10, pp. 4615-4637 . https://doi.org/10.1007/s00018-021-03802-0
CELLULAR AND MOLECULAR LIFE SCIENCES
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that occurs due to brain injury or inflammation-induced demyelination (
Autor:
Paula Solervicens, P Muñoz, Ulises Ríos, González R, Jimena Hermosilla, Javier Moran, Pablo R. Moya, Oscar Urrejola, Juan Pablo Jiménez
Publikováno v:
Revista médica de Chile v.148 n.2 2020
SciELO Chile
CONICYT Chile
instacron:CONICYT
SciELO Chile
CONICYT Chile
instacron:CONICYT
Background: A history of child abuse is common and has a significant impact in the clinical course of patients diagnosed with bipolar disorders (BD). Aims: To assess the frequency of child abuse experiences in patients BD type I and to evaluate its a