Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Pablo Prieto Matos"'
Autor:
Noemi Ferrito, Juan Báez-Flores, Mario Rodríguez-Martín, Julián Sastre-Rodríguez, Alessio Coppola, María Isidoro-García, Pablo Prieto-Matos, Jesus Lacal
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8563 (2024)
RASopathies are a group of related genetic disorders caused by mutations in genes within the RAS/MAPK signaling pathway. This pathway is crucial for cell division, growth, and differentiation, and its disruption can lead to a variety of developmental
Externí odkaz:
https://doaj.org/article/77a15fd02540400c99f020faeb01582e
Autor:
Marta Isidro-Hernández, Ana Casado-García, Ninad Oak, Silvia Alemán-Arteaga, Belén Ruiz-Corzo, Jorge Martínez-Cano, Andrea Mayado, Elena G. Sánchez, Oscar Blanco, Ma Luisa Gaspar, Alberto Orfao, Diego Alonso-López, Javier De Las Rivas, Susana Riesco, Pablo Prieto-Matos, África González-Murillo, Francisco Javier García Criado, María Begoña García Cenador, Manuel Ramírez-Orellana, Belén de Andrés, Carolina Vicente-Dueñas, César Cobaleda, Kim E. Nichols, Isidro Sánchez-García
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The initial steps of B-cell acute lymphoblastic leukemia (B-ALL) development usually pass unnoticed in children. Several preclinical studies have shown that exposure to immune stressors triggers the transformation of preleukemic B cells to f
Externí odkaz:
https://doaj.org/article/7edbe4149620489b8ca43749dc557848
Autor:
Patricia González Ildefonso, Ana Belén Nieto Librero, Montserrat Martín Alonso, María Luisa Hernández Cerceño, Esther García Serrano, Pablo Prieto-Matos
Publikováno v:
Anales de Pediatría (English Edition), Vol 98, Iss 5, Pp 329-337 (2023)
Introduction: The acid-labile subunit (ALS) plays an important role in the endocrine effects of insulin-like growth factors (IGFs) on target tissues. Historically, it has attracted limited attention. The aim of our study was to describe the normal ra
Externí odkaz:
https://doaj.org/article/3dedaddc0e11444a8fd31d08b6d68074
Autor:
Mario Rodríguez-Martín, Juan Báez-Flores, Vanessa Ribes, María Isidoro-García, Jesus Lacal, Pablo Prieto-Matos
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 841 (2024)
RASopathies, a group of neurodevelopmental congenital disorders stemming from mutations in the RAS/MAPK pathway, present a unique opportunity to delve into the intricacies of complex neurological disorders. Afflicting approximately one in a thousand
Externí odkaz:
https://doaj.org/article/4c8aa995b5554e85b9935a3d60f683db
Autor:
Ana Casado-García, Marta Isidro-Hernández, Silvia Alemán-Arteaga, Belén Ruiz-Corzo, Susana Riesco, Pablo Prieto-Matos, Lucía Sánchez, Isidro Sánchez-García, Carolina Vicente-Dueñas
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
B-cell acute lymphoblastic leukemia (B-ALL) stands as the primary contributor to childhood cancer-related mortality on a global scale. The development of the most conventional forms of this disease has been proposed to be conducted by two different s
Externí odkaz:
https://doaj.org/article/6d4b227c03d74feebcef1b28c45d90df
Autor:
Guillermo Rodríguez-Hernández, Ana Casado-García, Marta Isidro-Hernández, Daniel Picard, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alberto Orfao, Oscar Blanco, Susana Riesco, Pablo Prieto-Matos, Francisco Javier García Criado, María Begoña García Cenador, Hanno Hock, Tariq Enver, Isidro Sanchez-Garcia, Carolina Vicente-Dueñas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ETV6-RUNX1 is almost exclusively associated with childhood B-cell acute lymphoblastic leukemia (B-ALL), but the consequences of ETV6-RUNX1 expression on cell lineage decisions during B-cell leukemogenesis are completely unknown. Clinically silent ETV
Externí odkaz:
https://doaj.org/article/b30e171f55164cd082c50a7a24ed634f
Autor:
Marta Isidro-Hernández, Silvia Alemán-Arteaga, Ana Casado-García, Belén Ruiz-Corzo, Susana Riesco, Pablo Prieto-Matos, Jorge Martínez-Cano, Lucía Sánchez, César Cobaleda, Isidro Sánchez-García, Carolina Vicente-Dueñas
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7562 (2022)
Leukemia is the most usual childhood cancer, and B-cell acute lymphoblastic leukemia (B-ALL) is its most common presentation. It has been proposed that pediatric leukemogenesis occurs through a “multi-step” or “multi-hit” mechanism that inclu
Externí odkaz:
https://doaj.org/article/6fcb55c894724879b3e36d4814338e87
Autor:
Patricia González Ildefonso, Ana Belén Nieto Librero, Montserrat Martín Alonso, María Luisa Hernández Cerceño, Esther García Serrano, Pablo Prieto-Matos
Publikováno v:
Anales de Pediatría. 98:329-337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d76205781c52c13bbafb3fcecda922e0
https://doi.org/10.1016/j.anpedi.2023.01.008
https://doi.org/10.1016/j.anpedi.2023.01.008
Autor:
Isidro Sánchez-García, Kim E. Nichols, Andreas Weiss, Carolina Vicente-Dueñas, Jun J. Yang, César Cobaleda, Manuel Ramírez-Orellana, Thomas Radimerski, María Begoña García Cenador, Francisco Javier García Criado, África González-Murillo, Pablo Prieto-Matos, Susana Riesco, Javier De Las Rivas, Diego Alonso-López, Alberto Orfao, Oscar Blanco, Jorge Martínez-Cano, Elena G. Sánchez, Dario Sterker, Alexandra Buhles, Silvia Alemán-Arteaga, Javier Raboso-Gallego, Christine Mann-Ran, Andrea Mayado, Ninad Oak, Marta Isidro-Hernández, Ana Casado-García
Supplementary Data from Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727afcdf4ae3e49d8ce4cc51b3aadc6f
https://doi.org/10.1158/0008-5472.22431237.v1
https://doi.org/10.1158/0008-5472.22431237.v1
Autor:
Ana Casado-García, Marta Isidro-Hernández, Ninad Oak, Andrea Mayado, Christine Mann-Ran, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alexandra Buhles, Dario Sterker, Elena G. Sánchez, Jorge Martínez-Cano, Oscar Blanco, Alberto Orfao, Diego Alonso-López, Javier De Las Rivas, Susana Riesco, Pablo Prieto-Matos, África González-Murillo, Francisco Javier García Criado, María Begoña García Cenador, Thomas Radimerski, Manuel Ramírez-Orellana, César Cobaleda, Jun J. Yang, Carolina Vicente-Dueñas, Andreas Weiss, Kim E. Nichols, Isidro Sánchez-García
Publikováno v:
Cancer Research. 82:1098-1109
Preventing development of childhood B-cell acute lymphoblastic leukemia (B-ALL), a disease with devastating effects, is a longstanding and unsolved challenge. Heterozygous germline alterations in the PAX5 gene can lead to B-ALL upon accumulation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b72de6fa5ba3d728c6fd3434d4803f
https://doi.org/10.1158/0008-5472.can-21-3386
https://doi.org/10.1158/0008-5472.can-21-3386