Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Pablo Porras"'
Autor:
Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp 1-22 (2021)
Abstract We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe
Externí odkaz:
https://doaj.org/article/07d2352966634fc58ef9a394d1092d67
Autor:
Pablo Porras, Elisabet Barrera, Alan Bridge, Noemi del-Toro, Gianni Cesareni, Margaret Duesbury, Henning Hermjakob, Marta Iannuccelli, Igor Jurisica, Max Kotlyar, Luana Licata, Ruth C. Lovering, David J. Lynn, Birgit Meldal, Bindu Nanduri, Kalpana Paneerselvam, Simona Panni, Chiara Pastrello, Matteo Pellegrini, Livia Perfetto, Negin Rahimzadeh, Prashansa Ratan, Sylvie Ricard-Blum, Lukasz Salwinski, Gautam Shirodkar, Anjalia Shrivastava, Sandra Orchard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The IMEx consortium provides one of the largest resources of curated, experimentally verified molecular interaction data. Here, the authors review how IMEx evolved into a fundamental resource for life scientists and describe how IMEx data can support
Externí odkaz:
https://doaj.org/article/1dcc4fce40a042d9b98ea3d25e21c5d2
Autor:
Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, D A B Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff‐Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 12, Pp 1-2 (2021)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/5d30269056c148bf87fd8eb20e9f3e1c
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The Parkinson’s disease-associated Leucine-rich repeat kinase 2 (LRRK2) is a complex multi-domain protein belonging to the Roco protein family, a unique group of G-proteins. Variants of this gene are associated with an increased risk of Parkinson
Externí odkaz:
https://doaj.org/article/fd6e575e1f274b7cbaf50c6a7d72d3ac
Autor:
Thomas Wallach, Katja Schellenberg, Bert Maier, Ravi Kiran Reddy Kalathur, Pablo Porras, Erich E Wanker, Matthias E Futschik, Achim Kramer
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003398 (2013)
Essentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular timing mechanisms regulating impo
Externí odkaz:
https://doaj.org/article/269b5e0039ae40f5896b6665e1412f93
Autor:
Martin H Schaefer, Jean-Fred Fontaine, Arunachalam Vinayagam, Pablo Porras, Erich E Wanker, Miguel A Andrade-Navarro
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31826 (2012)
Protein function is often modulated by protein-protein interactions (PPIs) and therefore defining the partners of a protein helps to understand its activity. PPIs can be detected through different experimental approaches and are collected in several
Externí odkaz:
https://doaj.org/article/90a977cd48ab464fa1b18f8bd503200a
Autor:
Gareth A Palidwor, Sergey Shcherbinin, Matthew R Huska, Tamas Rasko, Ulrich Stelzl, Anup Arumughan, Raphaele Foulle, Pablo Porras, Luis Sanchez-Pulido, Erich E Wanker, Miguel A Andrade-Navarro
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 3, p e1000304 (2009)
A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel alpha-helices. Alpha-rods are flexible and expose a large surface, which makes them suitable f
Externí odkaz:
https://doaj.org/article/e5001745c12f4778a1e58afef071e9d0
Autor:
Inigo Barrio-Hernandez, Jeremy Schwartzentruber, Anjali Shrivastava, Noemi del-Toro, Asier Gonzalez, Qian Zhang, Edward Mountjoy, Daniel Suveges, David Ochoa, Maya Ghoussaini, Glyn Bradley, Henning Hermjakob, Sandra Orchard, Ian Dunham, Carl A. Anderson, Pablo Porras, Pedro Beltrao
Publikováno v:
Nature Genetics, 55 (3)
Interacting proteins tend to have similar functions, influencing the same organismal traits. Interaction networks can be used to expand the list of candidate trait-associated genes from genome-wide association studies. Here, we performed network-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83c627d04041e4fc3c3bbe9f7b3a34
Autor:
Marta Iannuccelli, Juri Rappsilber, Matteo Pellegrini, Gautam Shirodkar, Colin W. Combe, Pablo Porras, Maria Jesus Martin, Eliot Ragueneau, Anjali Shrivastava, Livia Perfetto, Margaret Duesbury, Sangya Pundir, Xavier Watkins, Lukasz Salwinski, Sandra Orchard, Sylvain D. Vallet, Bálint Mészáros, Luana Licata, Simona Panni, Karyn How, Prashansa Ratan, Gianni Cesareni, Kalpana Panneerselvam, Odilia Lu, Henning Hermjakob, Sylvie Ricard-Blum, Elisabet Barrera, Noemi del Toro, Birgit H M Meldal
Publikováno v:
del Toro, N, Shrivastava, A, Ragueneau, E, Meldal, B, Combe, C, Barrera, E, Perfetto, L, How, K, Ratan, P, Shirodkar, G, Lu, O, Mészáros, B, Watkins, X, Pundir, S, Licata, L, Iannuccelli, M, Pellegrini, M, Martin, M J, Panni, S, Duesbury, M, Vallet, S D, Rappsilber, J, Ricard-Blum, S, Cesareni, G, Salwinski, L, Orchard, S, Porras, P, Panneerselvam, K & Hermjakob, H 2021, ' The IntAct database : Efficient access to fine-grained molecular interaction data ', Nucleic Acids Research, vol. 50, no. D1, pp. D648-D653 . https://doi.org/10.1093/nar/gkab1006
Nucleic Acids Research
Nucleic Acids Research, vol 50, iss D1
Nucleic Acids Research
Nucleic Acids Research, vol 50, iss D1
The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one millio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf456c7abad01c6b8254885ffe621e6f
https://doi.org/10.1093/nar/gkab1006
https://doi.org/10.1093/nar/gkab1006
Autor:
Henning Hermjakob, Livia Perfetto, Pablo Porras, Edith D. Wong, Sandra Orchard, Noemi del-Toro, Carles Pons, Birgit H M Meldal, Patrick Aloy
Publikováno v:
Nucleic Acids Research
The EMBL-EBI Complex Portal is a knowledgebase of macromolecular complexes providing persistent stable identifiers. Entries are linked to literature evidence and provide details of complex membership, function, structure and complex-specific Gene Ont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb4b7fab935350f6f9949c52fd53e65
https://doi.org/10.1093/nar/gkab077
https://doi.org/10.1093/nar/gkab077