Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pablo Pérez-Moreno"'
Autor:
Javiera Obreque, Luis Vergara-Gómez, Nicolás Venegas, Helga Weber, Gareth I. Owen, Pablo Pérez-Moreno, Pamela Leal, Juan Carlos Roa, Carolina Bizama
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-27 (2023)
Abstract In December 2022 the US Food and Drug Administration (FDA) removed the requirement that drugs in development must undergo animal testing before clinical evaluation, a declaration that now demands the establishment and verification of ex vivo
Externí odkaz:
https://doaj.org/article/53e2cfa4a35d4a9fae6d1f662c519da0
Publikováno v:
Diagnostics, Vol 13, Iss 19, p 3072 (2023)
MicroRNAs (miRNAs) constitute a subclass of non-coding RNAs that exert substantial influence on gene-expression regulation. Their tightly controlled expression plays a pivotal role in various cellular processes, while their dysregulation has been imp
Externí odkaz:
https://doaj.org/article/89eae576f91f4a489aade91c3303a321
Autor:
Pablo Pérez‐Moreno, Sebastián Indo, Ignacio Niechi, Hernán Huerta, Pablo Cabello, Lilian Jara, Francisco Aguayo, Manuel Varas‐Godoy, Verónica A. Burzio, Julio C. Tapia
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 347-362 (2020)
Endothelin‐1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin‐1 rely on its activation by endothelin‐converting enzyme‐1 (ECE1), which is expressed as four isoforms wi
Externí odkaz:
https://doaj.org/article/18a70dfd7d844727ac173a958ee71a6a
Autor:
Pablo Pérez-Moreno, Camila Quezada-Meza, Cristopher Chavez-Almarza, Ignacio Niechi, Eduardo Silva-Pavez, César Trigo-Hidalgo, Francisco Aguayo, Lilian Jara, Albano Cáceres-Verschae, Manuel Varas-Godoy, Víctor M. Díaz, Antonio García de Herreros, Verónica A. Burzio, Julio C. Tapia
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Endothelin-converting enzyme-1 (ECE1) activates the endothelin-1 peptide, which upregulates pathways that are related to diverse hallmarks of cancer. ECE1 is expressed as four isoforms differing in their N-terminal domains. Protein kinase CK2 phospho
Externí odkaz:
https://doaj.org/article/c5d15211b6f741cbb97cf35bac2c6ec9
Autor:
Julio C. Tapia, Sebastián Indo, Francisco Aguayo, Hernán Huerta, Lilian Jara, Pablo Pérez-Moreno, Ignacio Niechi, Manuel Varas-Godoy, Pablo Cabello, Verónica A. Burzio
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 347-362 (2020)
Molecular Oncology
Molecular Oncology
Endothelin‐1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin‐1 rely on its activation by endothelin‐converting enzyme‐1 (ECE1), which is expressed as four isoforms wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a91bee6beceb182426c7bbdb9b15ea
https://doaj.org/article/18a70dfd7d844727ac173a958ee71a6a
https://doaj.org/article/18a70dfd7d844727ac173a958ee71a6a
Publikováno v:
Cancers
Cancers, Vol 14, Iss 202, p 202 (2022)
Cancers, Vol 14, Iss 202, p 202 (2022)
Simple Summary Gastrointestinal (GI) cancers are high mortality malignancies due to late diagnosis, the presence of metastasis and drug resistance development. Novel and more reliable biomarkers and therapeutic targets are still needed for these dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c302e381f8e22fcb56370b556a4a37fd
Autor:
Nayan Chaudhary, Alejandro M. Chibly, Ann Collier, Jorge Martinalbo, Pablo Perez-Moreno, Heather M. Moore, Patricia Luhn, Ciara Metcalfe, Marc Hafner
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract As CDK4/6 inhibitor (CDK4/6i) approval changed treatment strategies for patients with hormone receptor-positive HER2-negative (HR+/HER2-) breast cancer (BC), understanding how exposure to CDK4/6i affects the tumor genomic landscape is critic
Externí odkaz:
https://doaj.org/article/150abe257c594c719c7fd97eca5f49ee
Autor:
Albano Caceres-Verschae, Ignacio Niechi, Víctor M. Díaz, Eduardo Silva-Pavez, Francisco Aguayo, Julio C. Tapia, César Trigo-Hidalgo, Camila Quezada-Meza, Manuel Varas-Godoy, Antonio García de Herreros, Cristopher Chavez-Almarza, Verónica A. Burzio, Lilian Jara, Pablo Pérez-Moreno
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Indexación: Scopus. Endothelin-converting enzyme-1 (ECE1) activates the endothelin-1 peptide, which upregulates pathways that are related to diverse hallmarks of cancer. ECE1 is expressed as four isoforms differing in their N-terminal domains. Prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f16f20b8c5d73e01bbdc8d17c7d3a22
https://www.frontiersin.org/article/10.3389/fonc.2020.01004/full
https://www.frontiersin.org/article/10.3389/fonc.2020.01004/full
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 4206, p 4206 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine
Long non-coding RNAs are sequences longer than 200 nucleotides that are involved in different normal and abnormal biological processes exerting their effect on proliferation and differentiation, among other cell features. Functionally, lncRNAs can re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b856602f8ef0f2fb5f7bb6d7dba5a41
https://doi.org/10.3390/jcm10184206
https://doi.org/10.3390/jcm10184206
Autor:
Pablo Pérez Moreno
No la mires. No la escuches. Buena o mala persona. La roca te corromperá. Han pasado casi diez años desde los eventos de Un mundo perfecto y la mente de Martín solo recuerda fragmentos de su antigua y peligrosa aventura; su vida ha continuado con
