Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pablo Montañés"'
Autor:
Auriane C. Ernault, Makiri Kawasaki, Benedetta Fabrizi, Pablo Montañés-Agudo, Shirley C. M. Amersfoorth, Rushd F. M. Al-Shama, Ruben Coronel, Joris R. De Groot
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Atrial fibrosis plays an important role in the development and persistence of atrial fibrillation by promoting reentry. Primary cilia have been identified as a regulator of fibroblasts (FB) activation and extracellular matrix (ECM) deposi
Externí odkaz:
https://doaj.org/article/ebebcfbda4be4769afb87a318b921dd0
Autor:
Guillermo de Cárcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montañés, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres, Rocío Sotillo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
PLK1 is a mitotic regulator overexpressed in cancer; however, whether this overexpression causally contributes to tumor development is unclear. Here the authors produce an inducible mouse model to overexpress PLK1 and show that actually this can act
Externí odkaz:
https://doaj.org/article/624e442f805148c5bac60f63e764f010
Autor:
Auriane C. Ernault, Arie O. Verkerk, Jason D. Bayer, Kedar Aras, Pablo Montañés-Agudo, Rajiv A. Mohan, Marieke Veldkamp, Mathilde R. Rivaud, Rosan de Winter, Makiri Kawasaki, Shirley C.M. van Amersfoorth, Eva R. Meulendijks, Antoine H.G. Driessen, Igor R. Efimov, Joris R. de Groot, Ruben Coronel
Publikováno v:
Heart rhythm, 19(9), 1461-1470. Elsevier
Background: Epicardial adipose tissue (EAT) accumulation is associated with cardiac arrhythmias. The effect of EAT secretome (EATs) on cardiac electrophysiology remains largely unknown. Objective: The purpose of this study was to investigate the arrh
Publikováno v:
Journal of molecular and cellular cardiology, 179, 72-79. Academic Press Inc.
Alternative splicing generates specialized protein isoforms that allow the heart to adapt during development and disease. The recent discovery that mutations in the splicing factor RNA-binding protein 20 (RBM20) cause a severe form of familial dilate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2f02de2b348fd195acbd039ec4b8e2
https://pure.amc.nl/en/publications/splicing-factors-in-the-heart(bcaef91f-bf13-4478-a2d4-f8bb8a48b4ed).html
https://pure.amc.nl/en/publications/splicing-factors-in-the-heart(bcaef91f-bf13-4478-a2d4-f8bb8a48b4ed).html
Autor:
Pablo Montañés-Agudo, Simona Aufiero, Eva N Schepers, Ingeborg van der Made, Lucia Cócera-Ortega, Auriane C Ernault, Stéphane Richard, Diederik W D Kuster, Vincent M Christoffels, Yigal M Pinto, Esther E Creemers
Publikováno v:
Cardiovascular research, 119(5), 1161-1174. Oxford University Press
Montañés-Agudo, P, Aufiero, S, Schepers, E N, van der Made, I, Cócera-Ortega, L, Ernault, A C, Richard, S, Kuster, D W D, Christoffels, V M, Pinto, Y M & Creemers, E E 2023, ' The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes ', Cardiovascular Research, vol. 119, no. 5, pp. 1161-1174 . https://doi.org/10.1093/cvr/cvad007
Cardiovascular Research, 119(5), 1161-1174. Oxford University Press
Montañés-Agudo, P, Aufiero, S, Schepers, E N, van der Made, I, Cócera-Ortega, L, Ernault, A C, Richard, S, Kuster, D W D, Christoffels, V M, Pinto, Y M & Creemers, E E 2023, ' The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes ', Cardiovascular Research, vol. 119, no. 5, pp. 1161-1174 . https://doi.org/10.1093/cvr/cvad007
Cardiovascular Research, 119(5), 1161-1174. Oxford University Press
Aims In the heart, splicing factors orchestrate the functional properties of cardiomyocytes by regulating the alternative splicing of multiple genes. Work in embryonic stem cells has shown that the splicing factor Quaking (QKI) regulates alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50ebc788e68dadde46220d5ca49892c
https://pure.amc.nl/en/publications/the-rnabinding-protein-qki-governs-a-musclespecific-alternative-splicing-program-that-shapes-the-contractile-function-of-cardiomyocytes(48df7777-6df4-415c-856b-d4c9b3858e67).html
https://pure.amc.nl/en/publications/the-rnabinding-protein-qki-governs-a-musclespecific-alternative-splicing-program-that-shapes-the-contractile-function-of-cardiomyocytes(48df7777-6df4-415c-856b-d4c9b3858e67).html
Autor:
Pablo Montañés-Agudo, Yigal M. Pinto
Publikováno v:
Circulation. 146:715-717
Autor:
Auriane Ernault, Arie Verkerk, Jason D. Bayer, Kedar Aras, Pablo Montañés-Agudo, Rajiv A. Mohan, Marieke Veldkamp, Mathilde Rivaud, Makiri Kawasaki, Shirley C.M. van Amersfoorth, Eva R. Meulendijks, Antoine H.G. Driessen, Igor R. Efimov, Joris R. de Groot, Ruben Coronel
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:82-83
Autor:
Auriane C Ernault, Ingeborg van der Made, Simona Casini, Simona Aufiero, Pablo Montañés-Agudo, Carol Ann Remme, Yigal M. Pinto, Esther E. Creemers
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
Journal of cell science, 135(1):jcs259191. Company of Biologists Ltd
article-version (VoR) Version of Record
Journal of cell science, 135(1):jcs259191. Company of Biologists Ltd
Eukaryotic genomes contain a tiny subset of ‘minor class’ introns with unique sequence elements that require their own splicing machinery. These minor introns are present in certain gene families with specific functions, such as voltage-gated Na+
Autor:
Pablo Montañés-Agudo, Simona Aufiero, Eva N. Schepers, Ingeborg van der Made, Yigal M. Pinto, Esther Creemers
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:161