Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pablo Martínez-Acedo"'
Autor:
Anthony C. Carvalloza, Bruce D. Pascal, Pablo Martínez-Acedo, Catherina Scharager-Tapia, Patrick R. Griffin, Ricardo Flefil, Graham M. West, Tina Moroni
Publikováno v:
Journal of the American Society for Mass Spectrometry. 26:2133-2140
The goal in proteomics to identify all peptides in a complex mixture has been largely addressed using various LC MS/MS approaches, such as data dependent acquisition, SRM/MRM, and data independent acquisition instrumentation. Despite these developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e71798f1fac65c0dd2e4830731c2f6
https://doi.org/10.1007/s13361-015-1229-4
https://doi.org/10.1007/s13361-015-1229-4
Publikováno v:
Journal of Mass Spectrometry. 49:257-265
Owing to its labile nature, a new role for cysteine sulfenic acid (-SOH) modification has emerged. This oxidative modification modulates protein function by acting as a redox switch during cellular signaling. The identification of proteins that under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2588a5b6f011cf0d8f6ded694c21411
https://doi.org/10.1002/jms.3336
https://doi.org/10.1002/jms.3336
Autor:
Daniel Pérez-Hernández, Jesús Vázquez, María Luisa Hernáez, Montserrat Carrascal, Concha Gil, Juan Miguel Redondo, Fernando García, Pedro Navarro, Marco Trevisan-Herraz, Pablo Martínez-Acedo, J.A. Bárcena, Enrique Calvo, Inmaculada Jorge, Elena Bonzón-Kulichenko, Keith Ashman, Raquel Mesa, Estefanía Núñez, Joaquín Abián
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Pedro J. Navarro et al.
The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures. However, interpretation of the large data sets generated by the
The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures. However, interpretation of the large data sets generated by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f27cb1fa49f3612845c860aa003785
https://doi.org/10.1021/pr4006958
https://doi.org/10.1021/pr4006958
Autor:
Srinivasa Subramaniam, Laura M. Bohn, Neelam Shahani, Kshitij Khare, Vincenzo Giovinazzo, Bruce D. Pascal, Pablo Martínez-Acedo, Supriya Swarnkar, Jenny Morgenweck, Catherina Scharager-Tapia
Publikováno v:
Science Signaling. 9
The striatum of the brain coordinates motor function. Dopamine-related drugs may be therapeutic to patients with striatal neurodegeneration, such as Huntington’s disease (HD) and Parkinson’s disease (PD), but these drugs have unwanted side effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df76ba459dde8022893574e03c6ecb74
https://doi.org/10.1126/scisignal.aaf6670
https://doi.org/10.1126/scisignal.aaf6670
Application of iTRAQ Reagents to Relatively Quantify the Reversible Redox State of Cysteine Residues
Autor:
David Sheehan, Jesús Vázquez, Brian McDonagh, José Antonio Bárcena, Pablo Martínez-Acedo, C. Alicia Padilla
Publikováno v:
International Journal of Proteomics
Cysteines are one of the most rarely used amino acids, but when conserved in proteins they often play critical roles in structure, function, or regulation. Reversible cysteine modifications allow for potential redox regulation of proteins. Traditiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94227d5119903162a203ce382dbbfa8
https://doi.org/10.1155/2012/514847
https://doi.org/10.1155/2012/514847
Autor:
Santiago Lamas, Eduardo Rial, Natalia Romero, Mariano Redondo-Horcajo, Pablo Martínez-Acedo, Antonio Martínez-Ruiz, Cátia F. Lourenço, José Antonio Enríquez, Jesús Vázquez, Nieves Movilla, Celia Quijano, Rafael Radi, Fernando Rodríguez-Pascual
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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10 páginas, 5 figuras -- PAGS nros. 356-365
Aims Cyclosporine A (CsA) has represented a fundamental therapeutic weapon in immunosupression for the past three decades. However, its clinical use is not devoid of side effects, among which hyperten
Aims Cyclosporine A (CsA) has represented a fundamental therapeutic weapon in immunosupression for the past three decades. However, its clinical use is not devoid of side effects, among which hyperten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9011ecf8e8be652928befbefbb75136b
https://doi.org/10.1093/cvr/cvq028
https://doi.org/10.1093/cvr/cvq028
Autor:
Jesús Vázquez, Pedro Navarro, Juan Miguel Redondo, Arántzazu Alfranca, Horacio Serrano, Estefanía Núñez, Pablo Martínez-Acedo, Inmaculada Jorge
Publikováno v:
Molecular & Cellular Proteomics. 8:1130-1149
Statistical models for the analysis of protein expression changes by stable isotope labeling are still poorly developed, particularly for data obtained by 16O/18O labeling. Besides large scale test experiments to validate the null hypothesis are lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f74f26a596911db28ea0891d8103bc4
https://doi.org/10.1074/mcp.m800260-mcp200
https://doi.org/10.1074/mcp.m800260-mcp200
Autor:
Kate S. Carroll, Perry Evans, Vadim N. Gladyshev, Neal S. Gould, Stefano M. Marino, Harry Ischiropoulos, Pablo Martínez-Acedo
Publikováno v:
Chemistrybiology. 22(7)
SummaryS-Acylation, S-glutathionylation, S-nitrosylation, and S-sulfenylation are prominent, chemically distinct modifications that regulate protein function, redox sensing, and trafficking. Although the biological significance of these modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396e1631b7f93a87eced056ea63a3a3c
https://pubmed.ncbi.nlm.nih.gov/26165157
https://pubmed.ncbi.nlm.nih.gov/26165157
Autor:
Lori A. Hazlehurst, Xiuling Li, David Hymel, Christoph Rader, Tina Moroni, Pablo Martínez-Acedo, Terrence R. Burke, Alex R. Nanna, Christopher G. Nelson, Rajesh R. Nair
Publikováno v:
Cell Chemical Biology. 24:433-442.e6
Selenomabs are engineered monoclonal antibodies with one or more translationally incorporated selenocysteine residues. The unique reactivity of the selenol group of selenocysteine permits site-specific conjugation of drugs. Compared with other natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce83ccc6b9e881b83e4e5ddee49fa7d
https://doi.org/10.1016/j.chembiol.2017.02.012
https://doi.org/10.1016/j.chembiol.2017.02.012
Autor:
Marisol Ruiz-Meana, Javier Inserte, Celia Fernandez-Sanz, Estefanía Núñez, Antonio Rodríguez-Sinovas, David Garcia-Dorado, Jesús Vázquez, Pablo Martínez-Acedo, Elisabet Miró-Casas, Victor Hernando, Ignasi Barba
Publikováno v:
Journal of molecular and cellular cardiology. 68
Mitochondria play a central role in the protection conferred by ischemic preconditioning (IP) by not fully elucidated mechanisms. We investigated whether IP protects mitochondria against ischemia-reperfusion (IR) injury through mechanisms independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85979a21ae8a4f78f91ae699221e30f0
https://pubmed.ncbi.nlm.nih.gov/24434643
https://pubmed.ncbi.nlm.nih.gov/24434643