Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pablo M. Casillas-Espinos"'
Autor:
Pablo M. Casillas‐Espinosa, Jennie Garcia‐Olivares, Rui Li, Crystal Li, Chungping Yu, Andrea E. Formella, Terence J. O'Brien
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1826-1836 (2024)
Abstract Objective We evaluated huperzine A treatment in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) model of genetic generalized epilepsy (GGE) with absence seizures. Methods Adult male GAERS (N = 15) were implanted with EEG recording e
Externí odkaz:
https://doaj.org/article/bcf50cc9ba54439390cd3c38753f2c5f
Autor:
Nishant K. Mishra, Jerome Engel, David S. Liebeskind, Vijay K. Sharma, Lawrence J. Hirsch, Scott E Kasner, Jacqueline A. French, Orrin Devinsky, Alon Friedman, Jesse Dawson, Terence J. Quinn, Magdy Selim, Adam de Havenon, Clarissa L. Yasuda, Fernando Cendes, Felix Benninger, Hitten P. Zaveri, Jorge G. Burneo, Padma Srivastava, Mamta Bhushan Singh, Rohit Bhatia, V.Y. Vishnu, Carla Bentes, Jose Ferro, Shennan Weiss, Adithya Sivaraju, Jennifer A. Kim, Marian Galovic, Emily J. Gilmore, Asla Pitkänen, Kathryn Davis, Lauren H. Sansing, Kevin N. Sheth, Jeanne T. Paz, Anuradha Singh, Sunil Sheth, Bradford B. Worrall, James C. Grotta, Pablo M. Casillas-Espinos, Zhibin Chen, John-Paul Nicolo, Bernard Yan, Patrick Kwan
Publikováno v:
Epilepsybehavior : EB. 127
Autor:
Glenn R. Yamakawa, Meshwa Patel, Runxuan Lin, Terence J. O'Brien, Richelle Mychasiuk, Pablo M. Casillas‐Espinosa
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1523-1531 (2023)
Abstract Objectives Growing evidence demonstrates a relationship between epilepsy and the circadian system. However, relatively little is known about circadian function in disease states, such as epilepsy. This study aimed to characterize brain and p
Externí odkaz:
https://doaj.org/article/b09075573573429ab4e896b4a16c581d
Autor:
Patricia G. Saletti, Wenzhu B. Mowrey, Wei Liu, Qianyun Li, Jesse McCullough, Roxanne Aniceto, I‐Hsuan Lin, Michael Eklund, Pablo M. Casillas‐Espinosa, Idrish Ali, Cesar Santana‐Gomez, Lisa Coles, Sandy R. Shultz, Nigel Jones, Richard Staba, Terence J. O'Brien, Solomon L. Moshé, Denes V. Agoston, Aristea S. Galanopoulou, for the EpiBioS4Rx Study Group
Publikováno v:
Epilepsia Open, Vol 8, Iss 2, Pp 586-608 (2023)
Abstract Objective We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recover
Externí odkaz:
https://doaj.org/article/0fa6ea6ae33d4d8783473bb3574a6e08
Autor:
Zining Liu, Peravina Thergarajan, Ana Antonic‐Baker, Zhibin Chen, Paul B. Sparks, Natasha A. Lannin, Patrick Kwan, Nigel C. Jones, Pablo M. Casillas‐Espinosa, Piero Perucca, Terence J. O'Brien, Shobi Sivathamboo
Publikováno v:
Epilepsia Open, Vol 8, Iss 1, Pp 46-59 (2023)
Abstract Objective Epilepsy is associated with an increased risk of cardiovascular disease and mortality. Whether cardiac structure and function are altered in epilepsy remains unclear. To address this, we conducted a systematic review and meta‐ana
Externí odkaz:
https://doaj.org/article/41d28ae52732432281edd50736966a1d
Autor:
Pablo M. Casillas-Espinosa, Runxuan Lin, Rui Li, Nanditha M. Nandakumar, Georgia Dawson, Emma L. Braine, Benoît Martin, Kim L. Powell, Terence J. O'Brien
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106217- (2023)
Rationale: Low-voltage-activated or T-type Ca2+ channels play a key role in the generation of seizures in absence epilepsy. We have described a homozygous, gain of function substitution mutation (R1584P) in the CaV3.2 T-type Ca2+ channel gene (Cacna1
Externí odkaz:
https://doaj.org/article/b0a167a094254b4caaf3662017799fba
Publikováno v:
Epilepsia Open, Vol 5, Iss 2, Pp 138-154 (2020)
Abstract There is a growing body of clinical and experimental evidence that neurodegenerative diseases and epileptogenesis after an acquired brain insult may share common etiological mechanisms. Acquired epilepsy commonly develops as a comorbid condi
Externí odkaz:
https://doaj.org/article/f9c0eb9e8bcc4c46963fcb13a1710235
Autor:
Kim L. Powell, Zining Liu, Claire L. Curl, Antonia J.A. Raaijmakers, Pragati Sharma, Emma L. Braine, Flavia M. Gomes, Shobi Sivathamboo, Vaughan G. Macefield, Pablo M. Casillas-Espinosa, Nigel C. Jones, Lea M. Delbridge, Terence J. O’Brien
Publikováno v:
Neurobiology of Disease, Vol 159, Iss , Pp 105505- (2021)
Objective: This study aimed to prospectively examine cardiac structure and function in the kainic acid-induced post-status epilepticus (post-KA SE) model of chronic acquired temporal lobe epilepsy (TLE), specifically to examine for changes between th
Externí odkaz:
https://doaj.org/article/2f278a222be74d4a903bacd65e7a477e
Autor:
Patricia G. Saletti, Idrish Ali, Pablo M. Casillas-Espinosa, Bridgette D. Semple, Christos Panagiotis Lisgaras, Solomon L. Moshé, Aristea S. Galanopoulou
Publikováno v:
Neurobiology of Disease, Vol 123, Iss , Pp 86-99 (2019)
Post-traumatic epilepsy (PTE) is diagnosed in 20% of individuals with acquired epilepsy, and can impact significantly the quality of life due to the seizures and other functional or cognitive and behavioral outcomes of the traumatic brain injury (TBI
Externí odkaz:
https://doaj.org/article/befb89fe79c14fd7b707fccd4ff52fc2
Autor:
Rhys D. Brady, Pablo M. Casillas-Espinosa, Denes V. Agoston, Edward H. Bertram, Alaa Kamnaksh, Bridgette D. Semple, Sandy R. Shultz
Publikováno v:
Neurobiology of Disease, Vol 123, Iss , Pp 8-19 (2019)
Posttraumatic epilepsy (PTE) is one of the most debilitating and understudied consequences of traumatic brain injury (TBI). It is challenging to study the effects, underlying pathophysiology, biomarkers, and treatment of TBI and PTE purely in human p
Externí odkaz:
https://doaj.org/article/040d54ea0a0248159b467b6e2ac74915