Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Pablo J. Álvarez"'
Autor:
Consolación Melguizo, Jose Prados, Raquel Luque, Raúl Ortiz, Octavio Caba, Pablo J. Álvarez, Beatriz Gonzalez, Antonia Aranega
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 12, Pp 16624-16635 (2012)
Carboplatin-paclitaxel is a reference regimen in the treatment of locally advanced or disseminated non-small cell lung cancer (NSCLC). This paper discusses the multidrug resistance developed with this drug combination, which is one of the major obsta
Externí odkaz:
https://doaj.org/article/c685080fe4c14bf68c5df57420223a03
Autor:
Antonia Aránega, Juan Marchal, Consolación Melguizo, Raúl Ortíz, Alberto Ramírez, Macarena Peran, Fernando Rodríguez, Jose Prados, Pablo J. Álvarez, Esmeralda Carrillo, Houria Boulaiz
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 11, Pp 7445-7458 (2011)
Breast cancer research has developed rapidly in the past few decades, leading to longer survival times for patients and opening up the possibility of developing curative treatments for advanced breast cancer. Our increasing knowledge of the biologica
Externí odkaz:
https://doaj.org/article/e1bc5db1e7094b2991d5f1c0dcd52a6a
Autor:
Antonio Jesús Láinez-Ramos-Bossini, Consolación Melguizo, Raul Ortiz Quesada, Gloria Perazzoli, Pablo J. Álvarez, Mario Rivera-Izquierdo, Laura Cabeza, Jose Prados
Publikováno v:
Expert Opinion on Biological Therapy. 19:233-248
Adipose-derived mesenchymal stem cells (ASCs) represent a new therapeutic strategy in biomedicine with many potential applications, especially in musculoskeletal disorders. Preclinical and clinical studies based on the administration of ASCs support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78a16879f28438d9fa6b46305460367
https://doi.org/10.1080/14712598.2019.1563069
https://doi.org/10.1080/14712598.2019.1563069
Publikováno v:
Nutrition and Cancer. 70:569-578
Curcumin, the main active compound of the curcuma root, shows antioxidant, anti-inflammatory, and antitumor properties which have been demonstrated in preclinical and clinical trials. Its antitumor activity is mediated by its ability to act directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e172819cd5197e9cbbce600a545c109
https://doi.org/10.1080/01635581.2018.1464347
https://doi.org/10.1080/01635581.2018.1464347
Autor:
Beatriz Clares, Raúl Ortiz, Consolación Melguizo, Jose Prados, Celia Vélez, Pablo J. Álvarez, Antonia Aránega, Laura Cabeza, José L. Arias
Publikováno v:
The AAPS Journal. 17:918-929
The clinical use of 5-fluorouracil, one of the drugs of choice in colon cancer therapy, is limited by a nonuniform oral absorption, a short plasma half-life, and by the development of drug resistances by malignant cells. We hypothesized that the form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0082eb119dbc02a680b3421a546d6dbf
https://doi.org/10.1208/s12248-015-9761-5
https://doi.org/10.1208/s12248-015-9761-5
Autor:
Alejandro Villagrasa, Fernando Rodríguez-Serrano, Jose Manuel Garrido, Antonia Aránega, Pablo J. Álvarez, Antonio Osuna
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 19:303-313
Exosomes are small extracellular vesicles secreted to the extracellular environment by several cell types, including tumor cells. It has been demonstrated that exosomes have an important role in intercellular communication, but they have recently bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c12ae5f753f3238e58ad542742575c
https://doi.org/10.1007/s10911-015-9332-5
https://doi.org/10.1007/s10911-015-9332-5
Autor:
Jose Prados, Esther Carrasco, Fernando Rodríguez-Serrano, Ibtissam Messouri, Consolación Melguizo, Pablo J. Álvarez, Antonia Aránega, Rachid Chahboun, Enrique Alvarez-Manzaneda, María Isabel Vázquez-Vázquez
Publikováno v:
European Journal of Medicinal Chemistry. 79:1-12
This article describes the antitumor properties of a new family of merosesquiterpenes, which were synthesized by Diels–Alder cycloaddition of the labdane diene trans-communic acid, highly abundant in Cupressus sempervirens, or its methyl ester, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997f091879c9bc7e9fc416f00dc08fc9
https://doi.org/10.1016/j.ejmech.2014.03.071
https://doi.org/10.1016/j.ejmech.2014.03.071
Autor:
Jose Prados, Consolación Melguizo, A. Aránega, Laura Cabeza, Fernando Rodríguez-Serrano, Gloria Perazzoli, Raúl Ortiz, Pablo J. Álvarez
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 13:1204-1216
The number of patients with colorectal cancer, the third most frequently diagnosed malignancy in the world, has increased markedly over the past 20 years and will continue to increase in the future. Despite recent advances in chemotherapy, currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a9bee30215479832e86fe5758cd8a
https://doi.org/10.2174/18715206113139990325
https://doi.org/10.2174/18715206113139990325
Autor:
Jose Prados, Antonia Aránega, Raúl Ortiz, Fernando Rodríguez-Serrano, Inmaculada Robles-Fernandez, Consolación Melguizo, Ana R. Rama, Pablo J. Álvarez, Enrique Alvarez-Manzaneda
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 8:203-215
Cancer is the main cause of death in developing countries. Its development requires multiple steps in which the occurrence of certain events determines the state transition from a normal to a tumor cell. These events are related to the loss of mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9220288340be4c1b9ab056256f07c2
https://doi.org/10.2174/1574891x113089990034
https://doi.org/10.2174/1574891x113089990034
Autor:
Jaime Antonio Oliver, Cristina Jiménez-Luna, Consolación Melguizo, Octavio Caba, A. Aránega, Fernando Rodríguez-Serrano, José C. Prados, Pablo J. Álvarez
Publikováno v:
Recent Patents on Biomarkers. 3:110-119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b090c09b882321101f4e722d54a547a7
https://doi.org/10.2174/2210309011303030003
https://doi.org/10.2174/2210309011303030003