Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Pablo I, Nikel"'
Autor:
Manuel Nieto-Domínguez, Aboubakar Sako, Kasper Enemark-Rasmussen, Charlotte Held Gotfredsen, Daniela Rago, Pablo I. Nikel
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Fluorinated amino acids serve as an entry point for establishing new-to-Nature chemistries in biological systems, and novel methods are needed for the selective synthesis of these building blocks. In this study, we focused on the enzymatic s
Externí odkaz:
https://doaj.org/article/049232b111b04c82b66602c0a5cf1c8d
Autor:
Enrico Orsi, Lennart Schada von Borzyskowski, Stephan Noack, Pablo I. Nikel, Steffen N. Lindner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Achieving cost-competitive bio-based processes requires development of stable and selective biocatalysts. Their realization through in vitro enzyme characterization and engineering is mostly low throughput and labor-intensive. Therefore, str
Externí odkaz:
https://doaj.org/article/6572b641865e49c0a19309dde2ab21ea
Autor:
Yannic S. Ackermann, Jan de Witt, Mariela P. Mezzina, Christoph Schroth, Tino Polen, Pablo I. Nikel, Benedikt Wynands, Nick Wierckx
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Bio-upcycling of plastics is an emerging alternative process that focuses on extracting value from a wide range of plastic waste streams. Such streams are typically too contaminated to be effectively processed using traditional recycling tec
Externí odkaz:
https://doaj.org/article/d3045fcc20144667a3fa442714adecda
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Paenibacillus polymyxa is a non‐pathogenic, Gram‐positive bacterium endowed with a rich and versatile metabolism. However interesting, this bacterium has been seldom used for bioproduction thus far. In this study, we engineered P. polymy
Externí odkaz:
https://doaj.org/article/462df2868a654271967fcdfc67e60dd1
Autor:
Laura Pause, Anna Weimer, Nicolas T. Wirth, Anh Vu Nguyen, Claudius Lenz, Michael Kohlstedt, Christoph Wittmann, Pablo I. Nikel, Bin Lai, Jens O. Krömer
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract Providing an anodic potential in a bio‐electrochemical system to the obligate aerobe Pseudomonas putida enables anaerobic survival and allows the cells to overcome redox imbalances. In this setup, the bacteria could be exploited to produce
Externí odkaz:
https://doaj.org/article/88cacac332a543de822f59d6844b9bde
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Thymidylate kinases (TMPKs) play an essential role in DNA biosynthesis across all domains of life by catalyzing dTMP phosphorylation to dTDP. In Pseudomonas putida KT2440, a model Gram-negative soil bacterium, tmk is disrupted by a 65-kb gen
Externí odkaz:
https://doaj.org/article/3028ca7db09342f291900aafd12e2812
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 9, Pp 2426-2438 (2022)
Summary Randomized strain and pathway engineering are critical to improving microbial cell factory performance, calling for the development of high‐throughput screening and selection systems. To facilitate this effort, we have developed two 96‐we
Externí odkaz:
https://doaj.org/article/2136c7bbe2b0494e8c786b7a6de19e97
Autor:
Sheng‐Jie Yue, Peng Huang, Song Li, Yu‐Yuan Cai, Wei Wang, Xue‐Hong Zhang, Pablo I. Nikel, Hong‐Bo Hu
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 9, Pp 2324-2336 (2022)
Summary Pseudomonas chlororaphis is a non‐pathogenic, plant growth‐promoting rhizobacterium that secretes phenazine compounds with broad‐spectrum antibiotic activity. Currently available genome‐editing methods for P. chlororaphis are based on
Externí odkaz:
https://doaj.org/article/50a29588711a4f0493846f1dc48e5c7d
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 8, Pp 2250-2265 (2022)
Summary The potential of LacI/Ptrc, XylS/Pm, AlkS/PalkB, CprK/PDB3 and ChnR/PchnB regulatory nodes, recruited from both Gram‐negative and Gram‐positive bacteria, as the source of parts for formatting expression cargoes following the Standard Euro
Externí odkaz:
https://doaj.org/article/af0e1d05f0554fa6bbd7ef5d2c761260
Publikováno v:
mSystems, Vol 8, Iss 3 (2023)
ABSTRACT The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (
Externí odkaz:
https://doaj.org/article/cd1f0d54c1ac42c3930740990e16029a