Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pablo Hollstein"'
Autor:
Karen Cichowski, Richard Marais, Jennifer A. Wargo, Keith Flaherty, Scott Granter, Martin McMahon, Roderick T. Bronson, Ludwine Messiaen, Zachary A. Cooper, Dennie T. Frederick, Pablo Hollstein, Bryan Johnson, Ophélia Maertens
PDF file - 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480570f94b4e301f1168448e0a451863
https://doi.org/10.1158/2159-8290.22529835
https://doi.org/10.1158/2159-8290.22529835
Autor:
Karen Cichowski, Richard Marais, Jennifer A. Wargo, Keith Flaherty, Scott Granter, Martin McMahon, Roderick T. Bronson, Ludwine Messiaen, Zachary A. Cooper, Dennie T. Frederick, Pablo Hollstein, Bryan Johnson, Ophélia Maertens
PDF file - 96K, Schwann cells (RT4) expressing an inducible RAF construct (∆RAF:ER) were treated with the indicated concentrations of hydroxy-tamoxifen (4-OHT) in the absence and presence of a short hairpin RNA (shRNA) specific for NF1. RAS-GTP lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12561c3890b197a6ba849eb361b21b9
https://doi.org/10.1158/2159-8290.22529841.v1
https://doi.org/10.1158/2159-8290.22529841.v1
Autor:
Karen Cichowski, Richard Marais, Jennifer A. Wargo, Keith Flaherty, Scott Granter, Martin McMahon, Roderick T. Bronson, Ludwine Messiaen, Zachary A. Cooper, Dennie T. Frederick, Pablo Hollstein, Bryan Johnson, Ophélia Maertens
PDF file - 175K, Dose response curves for PLX4720 in BRAFV600E mutant melanoma cell lines (WM3526 (A) and A375 (B)) in the absence or presence of a short hairpin RNA (shRNA) specific for NF1. Cells were treated with PLX4720 at the indicated concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b303d9ab150af501d17a3b4c04dfdf6
https://doi.org/10.1158/2159-8290.22529838.v1
https://doi.org/10.1158/2159-8290.22529838.v1
Autor:
Karen Cichowski, Richard Marais, Jennifer A. Wargo, Keith Flaherty, Scott Granter, Martin McMahon, Roderick T. Bronson, Ludwine Messiaen, Zachary A. Cooper, Dennie T. Frederick, Pablo Hollstein, Bryan Johnson, Ophélia Maertens
PDF file - 84K, Supplementary Table 1. NF1 and BRAF mutations identified in human melanoma cell lines. Data were generated in this study when specified and collected from publicly available databases. (CCLE: Cancer Cell Line Encyclopedia, COSMIC: Cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bed57fb5f3d27a957feea6781923264
https://doi.org/10.1158/2159-8290.22529832.v1
https://doi.org/10.1158/2159-8290.22529832.v1
Autor:
Richard M. Watanabe, Kerry R. Wiles, Kimberly Colby, Narisu Narisu, Julie A. Douglas, Leonid Segal, Tasha E. Fingerlin, Elizabeth R. Hauser, Pablo Hollstein, Kimberly F. Doheny, Victoria L. Magnuson, Kathleen M. Humphreys, Michael P. Epstein, Soumitra Ghosh, David Rha, Rachel Porter, Jason Tovar, Yong D. Suh, Jaakko Tuomilehto, William Hagopian, Francis S. Collins, Chun Li, Arun M. Unni, Carrie Pfahl, Laura J. Scott, Jason E. Hill, Anabelle Morales-Mena, George Lin, Thomas A. Buchanan, Konstantinos N. Lazaridis, Elizabeth W. Pugh, Peggy P. White, Roshni A. Kasad, Peter S. Chines, Anne U. Jackson, Kristin Patzkowski, Jessica Lambert, Michael R. Erdos, Heather M. Stringham, Timo T. Valle, Richard N. Bergman, Karen L. Mohlke, Kaisa Silander, Christian Welch, William L. Duren, Michael Boehnke
Publikováno v:
Diabetes. 53:821-829
The aim of the Finland-United States Investigation of NIDDM Genetics (FUSION) study is to identify genes that predispose to type 2 diabetes or are responsible for variability in diabetes-related traits via a positional cloning and positional candidat
Autor:
Kaisa Silander, Laura J. Scott, Michael R. Erdos, Francis S. Collins, Michael Boehnke, Tasha E. Fingerlin, Karen L. Mohlke, Anne U. Jackson, Pablo Hollstein
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(26)
To facilitate positional cloning of complex trait susceptibility loci, we are investigating methods to reduce the effort required to identify trait-associated alleles. We examined primer extension analysis by matrix-assisted laser desorption/ionizati
Autor:
Panagiotis Deloukas, Richard M. Watanabe, Narisu Narisu, Kaisa Silander, Pablo Hollstein, Timo T. Valle, George Stavrides, Michael Boehnke, Jaakko Tuomilehto, Karen N. Conneely, Michael R. Erdos, Andrew D. Skol, Laura J. Scott, Francis S. Collins, Chun Li, Sharanjeet K. Dhanjal, Anne U. Jackson, Karen L. Mohlke, Sarah E. Hunt, Tasha E. Fingerlin, Peter S. Chines, Erin C. Peck, Richard N. Bergman
Publikováno v:
Europe PubMed Central
The Finland-United States Investigation Of NIDDM Genetics (FUSION) study aims to identify genetic variants that predispose to type 2 diabetes by studying affected sibling pair families from Finland. Chromosome 20 showed our strongest initial evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f34cd0d2ec621d36ebd54ca38b9311
http://europepmc.org/abstract/med/15047633
http://europepmc.org/abstract/med/15047633