Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Pablo Henríquez"'
Autor:
Daniel Sandoval, Jessica Mella, Jorge Ojeda, Francisca Bermedo-García, Marcela Low, Sylvain Marcellini, Maite A. Castro, Mariana Casas, Enrique Jaimovich, Juan Pablo Henríquez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-15 (2024)
Abstract Background Vitamin C plays key roles in cellular homeostasis, functioning as a potent antioxidant and a positive regulator of cell differentiation. In skeletal muscle, the vitamin C/sodium co-transporter SVCT2 is preferentially expressed in
Externí odkaz:
https://doaj.org/article/cdde513d3af042a18527c1170c826e99
Autor:
Beatriz Carnicero, Ricardo Fuentes, Nataly Sanhueza, Humberto Mattos, Constanza Aguirre-Campos, David Contreras, Eduardo Troncoso, Juan Pablo Henríquez, Sebastián Boltaña
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27874- (2024)
Saxitoxin (STX) represents a marine toxin of significant concern due to its deleterious implications for aquatic ecosystems and public food safety. As a potent paralytic agent, the role of STX in obstructing voltage-gated sodium channels (VGSCs) is w
Externí odkaz:
https://doaj.org/article/dd3ee692403943c681d42dd7eb498b0c
Autor:
Jorge Ojeda, Mayra Vergara, Ariel Ávila, Juan Pablo Henríquez, Michael Fehlings, Pia M. Vidal
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
Degenerative Cervical Myelopathy (DCM) is a progressive neurological condition characterized by structural alterations in the cervical spine, resulting in compression of the spinal cord. While clinical manifestations of DCM are well-documented, numer
Externí odkaz:
https://doaj.org/article/b648de2901924368881b6133536b7ddd
Autor:
Francisca Bermedo-García, Diego Zelada, Esperanza Martínez, Lucía Tabares, Juan Pablo Henríquez
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background In a broad variety of species, muscle contraction is controlled at the neuromuscular junction (NMJ), the peripheral synapse composed of a motor nerve terminal, a muscle specialization, and non-myelinating terminal Schwann cells. W
Externí odkaz:
https://doaj.org/article/fd675740d6234605aebb58ddbe690c20
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lithium chloride has been widely used as a therapeutic mood stabilizer. Although cumulative evidence suggests that lithium plays modulatory effects on postsynaptic receptors, the underlying mechanism by which lithium regulates synaptic trans
Externí odkaz:
https://doaj.org/article/9d2ddf998bd94992978f5e5e05e0f70e
Autor:
Pablo Rozas, Cristina Pinto, Francisca Martínez Traub, Rodrigo Díaz, Viviana Pérez, Daniela Becerra, Patricia Ojeda, Jorge Ojeda, Madison T. Wright, Jessica Mella, Lars Plate, Juan Pablo Henríquez, Claudio Hetz, Danilo B. Medinas
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice overexpressing ALS-link
Externí odkaz:
https://doaj.org/article/c57fbc2a7aa8401fb63f027829c4e9a4
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 11, Pp 2425-2426 (2022)
Externí odkaz:
https://doaj.org/article/fcb66862e72344d3a2f4f53def464005
Autor:
Viviana Pérez, Francisca Bermedo-Garcia, Diego Zelada, Felipe A. Court, Miguel Ángel Pérez, Marco Fuenzalida, Johanna Ábrigo, Claudio Cabello-Verrugio, Guillermo Moya-Alvarado, Juan Carlos Tapia, Vicente Valenzuela, Claudio Hetz, Francisca C. Bronfman, Juan Pablo Henríquez
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase the expression of the p75NTR pan
Externí odkaz:
https://doaj.org/article/0b9402c28e954f8a8bcf73f82d244d49
Autor:
Michelle Viscaino, Matias Talamilla, Juan Cristóbal Maass, Pablo Henríquez, Paul H. Délano, Cecilia Auat Cheein, Fernando Auat Cheein
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 917 (2022)
Artificial intelligence-assisted otologic diagnosis has been of growing interest in the scientific community, where middle and external ear disorders are the most frequent diseases in daily ENT practice. There are some efforts focused on reducing med
Externí odkaz:
https://doaj.org/article/ae13ada94a18427594f6b57ff96b0e71
Autor:
Jorge Ojeda, Francisca Bermedo-García, Viviana Pérez, Jessica Mella, Patricia Hanna, Daniel Herzberg, Rocío Tejero, Mario López-Manzaneda, Lucia Tabares, Juan Pablo Henríquez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The neuromuscular junction (NMJ) is the peripheral synapse that controls the coordinated movement of many organisms. The NMJ is also an archetypical model to study synaptic morphology and function. As the NMJ is the primary target of neuromuscular di
Externí odkaz:
https://doaj.org/article/eacf05ddf9324bcea91ed9e5988f2756