Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Pablo G Camara"'
Autor:
Carl H June, David M Barrett, Stephan A Grupp, Rong Fan, Marcela V Maus, Zhiliang Bai, Stefan Lundh, Dongjoo Kim, Steven Woodhouse, Regina M Myers, Pablo G Camara, J Joseph Melenhorst
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Autologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 molecule have transformed the therapeutic landscape in patients with highly refractory leukemia and lymphoma, and the use of donor-generated allog
Externí odkaz:
https://doaj.org/article/d1c8e9cf34dd480380636e72e6720295
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 11, p e1007509 (2019)
The prevailing paradigm for the analysis of biological data involves comparing groups of replicates from different conditions (e.g. control and treatment) to statistically infer features that discriminate them (e.g. differentially expressed genes). H
Externí odkaz:
https://doaj.org/article/6bb8c3c33afe4193a3634bc9cfdbabed
Autor:
Kiya W. Govek, Patrick Nicodemus, Yuxuan Lin, Jake Crawford, Artur B. Saturnino, Hannah Cui, Kristi Zoga, Michael P. Hart, Pablo G. Camara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract High-resolution imaging has revolutionized the study of single cells in their spatial context. However, summarizing the great diversity of complex cell shapes found in tissues and inferring associations with other single-cell data remains a
Externí odkaz:
https://doaj.org/article/02a233377c224214950752a02c01c4d4
Autor:
Rachael G. Aubin, Emma C. Troisi, Javier Montelongo, Adam N. Alghalith, Maclean P. Nasrallah, Mariarita Santi, Pablo G. Camara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The molecular mechanisms underlying ependymoma tumorigenesis remain poorly understood. Here, single cell analysis of posterior fossa primary tumours and distal metastases highlights the role of pro-inflammatory cytokines in promoting epithelial-to-me
Externí odkaz:
https://doaj.org/article/5813a87138be474398527991ba01b4e8
Publikováno v:
bioRxiv
SummarySingle-cell RNA-sequencing has transformed the study of biological tissues by enabling transcriptomic characterizations of their constituent cell states. Computational methods for gene expression deconvolution use this information to infer the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a02f627b3dfebe61182109f82318f6
https://doi.org/10.1101/2023.02.06.527318
https://doi.org/10.1101/2023.02.06.527318
Autor:
Zhiliang Bai, Steven Woodhouse, Ziran Zhao, Rahul Arya, Kiya Govek, Dongjoo Kim, Stefan Lundh, Alev Baysoy, Hongxing Sun, Yanxiang Deng, Yang Xiao, David M. Barrett, Regina M. Myers, Stephan A. Grupp, Carl H. June, Rong Fan, Pablo G. Camara, J. Joseph Melenhorst
Publikováno v:
Science Advances. 8
A notable number of acute lymphoblastic leukemia (ALL) patients develop CD19-positive relapse within 1 year after receiving chimeric antigen receptor (CAR) T cell therapy. It remains unclear if the long-term response is associated with the characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed543e5e89a2b01426898429c448b356
https://doi.org/10.1126/sciadv.abj2820
https://doi.org/10.1126/sciadv.abj2820
Autor:
Kiya W. Govek, Jake Crawford, Artur B. Saturnino, Kristi Zoga, Michael P. Hart, Pablo G. Camara
High-resolution imaging-based single-cell profiling has transformed the study of cells in their spatial context. However, the lack of quantitative methods that can summarize the great diversity of complex cell shapes found in tissues and infer associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9afeb7ec5664c1d22bc829bd24739ee
https://doi.org/10.1101/2022.05.19.492525
https://doi.org/10.1101/2022.05.19.492525
Autor:
Hao Wu, Peng Hu, Yugong Ho, Pablo G. Camara, Douglas J. Epstein, Michael T. Peel, Stephen A. Liebhaber, Sixing Chen
Publikováno v:
Protein & Cell
Protein & Cell, Vol 11, Iss 8, Pp 565-583 (2020)
Protein & Cell, Vol 11, Iss 8, Pp 565-583 (2020)
The anterior pituitary gland drives highly conserved physiologic processes in mammalian species. These hormonally controlled processes are central to somatic growth, pubertal transformation, fertility, lactation, and metabolism. Current cellular mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f0d25d2768b2362ea4663b8b81f632
http://europepmc.org/articles/PMC7381518
http://europepmc.org/articles/PMC7381518
Autor:
Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara
The thalamus is the principal information hub of the vertebrate brain, with essential roles in sensory and motor information processing, attention, and memory. The molecular mechanisms regulating the formation of thalamic nuclei are unclear. We apply
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d288952ee68ca8dd0312631781b8b514
https://doi.org/10.1101/2022.02.18.481097
https://doi.org/10.1101/2022.02.18.481097
Autor:
Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara
Publikováno v:
Cell Reports. 41:111768
The thalamus is the principal information hub of the vertebrate brain, with essential roles in sensory and motor information processing, attention, and memory. The complex array of thalamic nuclei develops from a restricted pool of neural progenitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bceba3dc362fc67cb3888882f1d8fb1
https://doi.org/10.1016/j.celrep.2022.111768
https://doi.org/10.1016/j.celrep.2022.111768