Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pablo Ferrón"'
Autor:
Rossana Passannante, Vanessa Gómez-Vallejo, Maialen Sagartzazu-Aizpurua, Laura Vignau Arsuaga, Pablo Marco-Moreno, Garazi Aldanondo, Ainara Vallejo-Illarramendi, Pablo Aguiar, Unai Cossío, Abraham Martín, Jonas Bergare, Lee Kingston, Charles S. Elmore, Miguel Angel Morcillo, Pablo Ferrón, Jesus M. Aizpurua, Jordi Llop
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 253 (2023)
Background and objective: The determination of pharmacokinetic properties of new chemical entities is a key step in the process of drug development. Positron emission tomography (PET) is an ideal technique to obtain both biodistribution and pharmacok
Externí odkaz:
https://doaj.org/article/ed7d132499034dc9b7f57f0c9ecdfc0f
Autor:
Garazi Aldanondo, Maite Eceiza, José I. Miranda, Ainara Vallejo-Illarramendi, Maialen Sagartzazu-Aizpurua, Pablo Marco-Moreno, Aitziber Irastorza, Pablo Ferrón, Jesus M. Aizpurua, Adolfo López de Munain, Haizpea Lasa-Fernández, Endika Torres, Naroa Dadie
Publikováno v:
European Journal of Medicinal Chemistry. 213:113160
The hypothesis of rescuing FKBP12/RyR1 interaction and intracellular calcium homeostasis through molecular “reshaping” of FKBP12 was investigated. To this end, novel 4-arylthioalkyl-1-carboxyalkyl-1,2,3-triazoles were designed and synthesized, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66a6ca5e17c6c75233ec206da4a3755
https://doi.org/10.1016/j.ejmech.2021.113160
https://doi.org/10.1016/j.ejmech.2021.113160
Publikováno v:
Tetrahedron. 66:3187-3194
Conformationally restricted NADH peptidomimetics 4a–e, characterized by the presence of a (1,4-dihydronicotinamide)-(β-lactam) moiety, have been synthesized and used to study the Mg2+ cation-promoted asymmetric reduction of alkyl aroylformates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab89be882e2217e4f35a4d365a4da46
https://doi.org/10.1016/j.tet.2010.02.085
https://doi.org/10.1016/j.tet.2010.02.085
Autor:
Ana Benito, José I. Santos, José I. Miranda, Enrique Gómez-Bengoa, Raluca M. Fratila, Pablo Ferrón, Claudio Palomo, Jesus M. Aizpurua
Publikováno v:
The Journal of organic chemistry. 74(17)
Mechanistic details of the Mg(2+) ion-activated enantioselective reduction of methyl benzoylformate have been investigated at a B3LYP/6-31G* theory level, using peptide NADH models 1 rigidified with a beta-lactam ring. Computation of the reaction pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c36fb70edfb67a07898b192186d77d
https://pubmed.ncbi.nlm.nih.gov/19642693
https://pubmed.ncbi.nlm.nih.gov/19642693