Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pablo Federico Sirkin"'
Autor:
Abel L. Carcagno, Omar Pedro Pignataro, Eduardo T. Cánepa, Marcela González-Cid, María Elida Scassa, Pablo Federico Sirkin, Julieta M. Ceruti, Mariela C. Marazita
Publikováno v:
DNA Repair. 6:626-638
Genome integrity and cell proliferation and survival are regulated by an intricate network of pathways that includes cell cycle checkpoints, DNA repair and recombination, and programmed cell death. It makes sense that there should be a coordinated re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5d1a83378f1bf1a6ce2aa4160c1805
https://doi.org/10.1016/j.dnarep.2006.12.003
https://doi.org/10.1016/j.dnarep.2006.12.003
Autor:
Mariela C. Marazita, Maria Florencia Ogara, Eduardo T. Cánepa, Pablo Federico Sirkin, María Elida Scassa, Abel L. Carcagno, Julieta M. Ceruti
Publikováno v:
IUBMB Life. 59:419-426
The cyclin D-Cdk4-6/INK4/Rb/E2F pathway plays a key role in controlling cell growth by integrating multiple mitogenic and antimitogenic stimuli. The members of INK4 family, comprising p16(INK4a), p15(INK4b), p18(INK4c), and p19(INK4d), block the prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087aabe323dbb16f7d9f2234cf80f7ab
https://doi.org/10.1080/15216540701488358
https://doi.org/10.1080/15216540701488358
Autor:
Silvina Veronica Sonzogni, Maria Florencia Ogara, Eduardo T. Cánepa, Daniela Susana Castillo, Pablo Federico Sirkin, J. Pablo Radicella
DNA is continuously exposed to damaging agents that can lead to changes in the genetic information with adverse consequences. Nonetheless, eukaryotic cells have mechanisms such as the DNA damage response (DDR) to prevent genomic instability. The DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c80cc7e8f9ff4b05ae4bda6c38c4d8
https://link.springer.com/article/10.1007/s11010-014-2205-1
https://link.springer.com/article/10.1007/s11010-014-2205-1
Autor:
Pablo Federico Sirkin, Mariela C. Marazita, Silvina Veronica Sonzogni, Maria Florencia Ogara, Abel L. Carcagno, Julieta M. Ceruti, Eduardo T. Cánepa
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61143 (2013)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
The maintenance of genomic integrity is of main importance to the survival and health of organisms which are continuously exposed to genotoxic stress. Cells respond to DNA damage by activating survival pathways consisting of cell cycle checkpoints an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3516662ab6a90d70c3c3ef52e0908b18
http://europepmc.org/articles/PMC3625165?pdf=render
http://europepmc.org/articles/PMC3625165?pdf=render
Autor:
Pablo Federico Sirkin, Julieta M. Ceruti, Mariela C. Marazita, Maria Florencia Ogara, Silvina Veronica Sonzogni, Abel L. Carcagno, Eduardo T. Cánepa
Publikováno v:
IUBMB life. 61(5)
E2F1, a member of the E2F family of transcription factors, plays a critical role in controlling both cell cycle progression and apoptotic cell death in response to DNA damage and oncogene activation. Following genotoxic stresses, E2F1 protein is stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03566e9038a2651d9f2e23fb287a2845
https://pubmed.ncbi.nlm.nih.gov/19391166
https://pubmed.ncbi.nlm.nih.gov/19391166
Autor:
Mariela C. Marazita, Pablo Federico Sirkin, Julieta M. Ceruti, Eduardo T. Cánepa, María Elida Scassa, Abel L. Carcagno
p19INK4d promotes survival of several cell lines after UV irradiation due to enhanced DNA repair, independently of CDK4 inhibition. To further understand the action of p19INK4d in the cellular response to DNA damage, we aimed to elucidate whether thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f2b793931c12b2065be5dc247cd0b2
http://www.sciencedirect.com/science/article/pii/S1357272508004846
http://www.sciencedirect.com/science/article/pii/S1357272508004846