Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pablo E. García-Nieto"'
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-20 (2019)
Abstract Background Somatic mutations in healthy tissues contribute to aging, neurodegeneration, and cancer initiation, yet they remain largely uncharacterized. Results To gain a better understanding of the genome-wide distribution and functional imp
Externí odkaz:
https://doaj.org/article/8a832c394bf64d61ac4b4445ba96f901
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009939 (2022)
RNA sequencing has been widely used as an essential tool to probe gene expression. While standard practices have been established to analyze RNA-seq data, it is still challenging to interpret and remove artifactual signals. Several biological and tec
Externí odkaz:
https://doaj.org/article/169983e041c144fea4ce3b0cc481ba73
Publikováno v:
PLoS computational biology. 18(3)
RNA sequencing has been widely used as an essential tool to probe gene expression. While standard practices have been established to analyze RNA-seq data, it is still challenging to interpret and remove artifactual signals. Several biological and tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c080113903e244cca3c4d16766d60f6
https://pubmed.ncbi.nlm.nih.gov/35324895
https://pubmed.ncbi.nlm.nih.gov/35324895
BackgroundRNA sequencing has been widely used as an essential tool to probe gene expression. While standard practices have been established to analyze RNA-seq data, it is still challenging to detect and remove artifactual signals. Several factors suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6e37e945ac6cfe029884f6704ee8c4
https://doi.org/10.1101/2021.04.27.441712
https://doi.org/10.1101/2021.04.27.441712
Autor:
Brian S. Perez, Erin K. Schwartz, Rafael E. Herrera, Pablo E. García-Nieto, Ashby J. Morrison, Ka Man Wong, Devin A. King
Publikováno v:
Mutat Res
Exposure to the ultraviolet (UV) radiation in sunlight creates DNA lesions, which if left unrepaired can induce mutations and contribute to skin cancer. The two most common UV-induced DNA lesions are the cis-syn cyclobutane pyrimidine dimers (CPDs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b685844a9efe6ba646a2ef1215b4f50b
https://doi.org/10.1016/j.mrfmmm.2021.111758
https://doi.org/10.1016/j.mrfmmm.2021.111758
Autor:
Ashby J. Morrison, Devin A. King, Rafael E. Herrera, Philippe Collas, Jonas Paulsen, Pablo E. García-Nieto, Erin K. Schwartz
Publikováno v:
The EMBO Journal. 36:2829-2843
The development of many sporadic cancers is directly initiated by carcinogen exposure. Carcinogens induce malignancies by creating DNA lesions (i.e., adducts) that can result in mutations if left unrepaired. Despite this knowledge, there has been rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ef96d09f73be9da8a449d06201f56a
https://doi.org/10.15252/embj.201796717
https://doi.org/10.15252/embj.201796717
Publikováno v:
Genome Biology
Genome Biology, Vol 20, Iss 1, Pp 1-20 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-20 (2019)
Background Somatic mutations in healthy tissues contribute to aging, neurodegeneration, and cancer initiation, yet they remain largely uncharacterized. Results To gain a better understanding of the genome-wide distribution and functional impact of so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d00978cfb8a6ae8a2440f17566aa103
https://doi.org/10.1101/668624
https://doi.org/10.1101/668624
Autor:
Egan L Peltan, Alexander P. Paraschuk, Ka Man Wong, Graeme J. Gowans, Ashby J. Morrison, Wei Yao, Sean L. Beckwith, Devin A. King, Laura R. Lee, Tessa L. Eckley, Erin K. Schwartz, Pablo E. García-Nieto
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007216 (2018)
PLoS Genetics
PLoS Genetics
Chromatin remodeling complexes are essential for gene expression programs that coordinate cell function with metabolic status. However, how these remodelers are integrated in metabolic stability pathways is not well known. Here, we report an expansiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5db501bbd9e4d2e3ed049eb98ec7d67
https://doi.org/10.1101/184440
https://doi.org/10.1101/184440
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 216-218 (2014)
Genomics Data
Genomics Data
Cells regulate transcription by coordinating the activities of multiple histone modifying complexes. We recently identified the yeast histone H4 methyltransferase Set5 and discovered functional overlap with the histone H3 methyltransferase Set1 in ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d77f54edfbe628358c34028ed0c63c
https://doi.org/10.1016/j.gdata.2014.07.001
https://doi.org/10.1016/j.gdata.2014.07.001
Autor:
Ashby J. Morrison, Glòria Mas Martín, Devin A. King, Sean R. Collins, Pablo E. García-Nieto, Nevan J. Krogan, Or Gozani, Richard Alexander, Erin M. Green
Publikováno v:
Martín, GM; King, DA; Green, EM; Garcia-Nieto, PE; Alexander, R; Collins, SR; et al.(2014). Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons. Epigenetics, 9(4), 513-522. doi: 10.4161/epi.27645. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2rw4p9pc
Epigenetics, vol 9, iss 4
Epigenetics, vol 9, iss 4
A complex interplay between multiple chromatin modifiers is critical for cells to regulate chromatin structure and accessibility during essential DNA-templated processes such as transcription. However, the coordinated activities of these chromatin mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a88d0ffe7dc10142da31e203a2f2a7
http://www.escholarship.org/uc/item/2rw4p9pc
http://www.escholarship.org/uc/item/2rw4p9pc