Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Pablo Cabezas"'
Autor:
Sonia Alcalá, Lara Villarino, Laura Ruiz-Cañas, José R. Couceiro, Miguel Martínez-Calvo, Adrián Palencia-Campos, Diego Navarro, Pablo Cabezas-Sainz, Iker Rodriguez-Arabaolaza, Alfonso Cordero-Barreal, Lucia Trilla-Fuertes, Juan A. Rubiolo, Sandra Batres-Ramos, Mireia Vallespinos, Cristina González-Páramos, Jéssica Rodríguez, Angelo Gámez-Pozo, Juan Ángel Fresno Vara, Sara Fra Fernández, Amparo Benito Berlinches, Nicolás Moreno-Mata, Ana María Torres Redondo, Alfredo Carrato, Patrick C. Hermann, Laura Sánchez, Susana Torrente, Miguel Ángel Fernández-Moreno, José L. Mascareñas, Bruno Sainz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-27 (2024)
Abstract Background Previous studies by our group have shown that oxidative phosphorylation (OXPHOS) is the main pathway by which pancreatic cancer stem cells (CSCs) meet their energetic requirements; therefore, OXPHOS represents an Achille’s heel
Externí odkaz:
https://doaj.org/article/a0e8a35f5983431287f4bb493ff1d8e0
Autor:
Ana Quelle-Regaldie, Nerea Gandoy-Fieiras, Paula Rodríguez-Villamayor, Sandra Maceiras, Ana Paula Losada, Mónica Folgueira, Pablo Cabezas-Sáinz, Antón Barreiro-Iglesias, María Villar-López, María Isabel Quiroga-Berdeal, Laura Sánchez, María Jesús Sobrido
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Niemann Pick disease type C (NPC) is an autosomal recessive neurodegenerative lysosomal disorder characterized by an accumulation of lipids in different organs. Clinical manifestations can start at any age and include hepatosplenomegaly, intellectual
Externí odkaz:
https://doaj.org/article/404006b531494bb6951427f80b353822
Autor:
Emilia Alors-Perez, Ricardo Blázquez-Encinas, Sonia Alcalá, Cristina Viyuela-García, Sergio Pedraza-Arevalo, Vicente Herrero-Aguayo, Juan M. Jiménez-Vacas, Andrea Mafficini, Marina E. Sánchez-Frías, María T. Cano, Fernando Abollo-Jiménez, Juan A. Marín-Sanz, Pablo Cabezas-Sainz, Rita T. Lawlor, Claudio Luchini, Laura Sánchez, Juan M. Sánchez-Hidalgo, Sebastián Ventura, Laura Martin-Hijano, Manuel D. Gahete, Aldo Scarpa, Álvaro Arjona-Sánchez, Alejandro Ibáñez-Costa, Bruno Sainz, Raúl M. Luque, Justo P. Castaño
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, requiring novel treatments to target both cancer cells and cancer stem cells (CSCs). Altered splicing is emerging as both a novel cancer hallmark and an attractive
Externí odkaz:
https://doaj.org/article/2e57a0d7fd7f42d6a9f88e1c0cae6aca
Autor:
Sandra Valle, Sonia Alcalá, Laura Martin-Hijano, Pablo Cabezas-Sáinz, Diego Navarro, Edurne Ramos Muñoz, Lourdes Yuste, Kanishka Tiwary, Karolin Walter, Laura Ruiz-Cañas, Marta Alonso-Nocelo, Juan A. Rubiolo, Emilio González-Arnay, Christopher Heeschen, Laura Garcia-Bermejo, Patrick C. Hermann, Laura Sánchez, Patricia Sancho, Miguel Ángel Fernández-Moreno, Bruno Sainz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Long-term cultures of pancreatic cancer stem cells (PaCSCs) are difficult to obtain. Here, the authors present a 2D culture method, based on the use of galactose, to establish cell cultures from pancreatic ductal adenocarcinoma xenotransplants enrich
Externí odkaz:
https://doaj.org/article/318cab6a23144c398f4c1aba8ef19747
Autor:
María Molina-Vega, Maite Asenjo-Plaza, María José Banderas-Donaire, María Dolores Hernández-Ollero, Silvia Rodríguez-Moreno, Juan J Álvarez-Millán, Pablo Cabezas-Sanchez, Fernando Cardona-Díaz, Juan Alcaide-Torres, Lourdes Garrido-Sánchez, Daniel Castellano-Castillo, Francisco J Tinahones, José C Fernández-García
Publikováno v:
Asian Journal of Andrology, Vol 22, Iss 4, Pp 372-378 (2020)
Erectile dysfunction (ED), a condition closely related to cardiovascular morbidity and mortality, is frequently associated with obesity. In this study, we aimed to determine the prevalence of ED and evaluate the associated risk factors in a cohort of
Externí odkaz:
https://doaj.org/article/3595b9c6db0840eda271501018499151
Autor:
Pablo Cabezas-Sainz, Jorge Guerra-Varela, María J. Carreira, Javier Mariscal, María Roel, Juan A. Rubiolo, Andrés A. Sciara, Miguel Abal, Luis M. Botana, Rafael López, Laura Sánchez
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Zebrafish (Danio rerio) is a model organism that has emerged as a tool for cancer research, cancer being the second most common cause of death after cardiovascular disease for humans in the developed world. Zebrafish is a useful m
Externí odkaz:
https://doaj.org/article/744eb7bc4a5640048bcf339d37548112
Autor:
Oscar A. Lenis-Rojas, Sandra Cordeiro, Marta Horta-Meireles, Jhonathan Angel Araujo Fernández, Sabela Fernández Vila, Juan Andrés Rubiolo, Pablo Cabezas-Sainz, Laura Sanchez, Alexandra R. Fernandes, Beatriz Royo
Publikováno v:
Molecules, Vol 26, Iss 18, p 5535 (2021)
Cisplatin and its derivatives are commonly used in chemotherapeutic treatments of cancer, even though they suffer from many toxic side effects. The problems that emerge from the use of these metal compounds led to the search for new complexes capable
Externí odkaz:
https://doaj.org/article/719b6affd54745608726e7a8ff19619b
Publikováno v:
Applied Sciences, Vol 11, Iss 16, p 7721 (2021)
Background: Zebrafish (Danio rerio) is a model organism for the study of human cancer. Compared with the murine model, the zebrafish model has several properties ideal for personalized therapies. The transparency of the zebrafish embryos and the deve
Externí odkaz:
https://doaj.org/article/5196c163c19a404caeefc63fd526b65c
Publikováno v:
Cuadernos de Trabajo Social, Vol 32, Iss 2 (2019)
Los cambios sociales que se están produciendo en nuestras sociedades exigen y obligan a los profesionales del Trabajo Social a afrontar nuevos retos en la forma de analizar y abordar la complejidad de las diversas realidades sociales. Ello explica q
Externí odkaz:
https://doaj.org/article/e5d80471f26442818186cb4b4335b1c7
Autor:
Ana Martínez-Escribano, Julia Maroto-García, Maximiliano Ruiz-Galdón, Rocío Barrios-Rodríguez, Juan J. Álvarez-Millán, Pablo Cabezas-Sánchez, Isaac Plaza-Andrades, María Molina-Vega, Francisco J. Tinahones, María Isabel Queipo-Ortuño, José Carlos Fernández-García
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1697 (2020)
Hypoandrogenemia, a frequent finding in men with obesity, is defined by low concentrations of serum testosterone. Although immunoassay (IA) is the most used method for the determination of this steroid in clinical practice, liquid chromatography-mass
Externí odkaz:
https://doaj.org/article/ff53d493d3cc4f0fb27b5f7668976bb7