Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pablo C. Echeverría"'
Autor:
Kaushik Bhattacharya, Lorenz Weidenauer, Tania Morán Luengo, Ellis C. Pieters, Pablo C. Echeverría, Lilia Bernasconi, Diana Wider, Yashar Sadian, Margreet B. Koopman, Matthieu Villemin, Christoph Bauer, Stefan G. D. Rüdiger, Manfredo Quadroni, Didier Picard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Hop, also known as Stip1 or Sti1, facilitates substrate transfer between the Hsp70 and Hsp90 molecular chaperones. Characterization of proteostasis-related pathways in STIP1 knock-out cell lines reveals that in eukaryotes Stip1 modulates the balance
Externí odkaz:
https://doaj.org/article/82875625c72b4d9c8c7eaaf0131c13bc
Publikováno v:
Advances in cancer research. 129
The molecular chaperone Hsp90 has attracted a lot of interest in cancer research ever since cancer cells were found to be more sensitive to Hsp90 inhibition than normal cells. Why that is has remained a matter of debate and is still unclear. In addit
Autor:
Gregory Segala, Marcela A. Bennesch, Nastaran Mohammadi Ghahhari, Deo Prakash Pandey, Pablo C. Echeverria, François Karch, Robert K. Maeda, Didier Picard
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Endosomal fusion depends on the HOPS and CORVET complexes but whether and how their subunits modulate signal transduction is not fully understood. Here, the authors show that the HOPS/CORVET subunits Vps11 and Vps18 are E3 ubiquitin ligases that are
Externí odkaz:
https://doaj.org/article/ce61553035444a5d9885729d73ae928a
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26044 (2011)
Understanding the functions of proteins requires information about their protein-protein interactions (PPI). The collective effort of the scientific community generates far more data on any given protein than individual experimental approaches. The l
Externí odkaz:
https://doaj.org/article/1b6a1b1e571740f3974f8aa3f3aa49c9