Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pablo C. Echeverría"'
Autor:
Kaushik Bhattacharya, Lorenz Weidenauer, Tania Morán Luengo, Ellis C. Pieters, Pablo C. Echeverría, Lilia Bernasconi, Diana Wider, Yashar Sadian, Margreet B. Koopman, Matthieu Villemin, Christoph Bauer, Stefan G. D. Rüdiger, Manfredo Quadroni, Didier Picard
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Hop, also known as Stip1 or Sti1, facilitates substrate transfer between the Hsp70 and Hsp90 molecular chaperones. Characterization of proteostasis-related pathways in STIP1 knock-out cell lines reveals that in eukaryotes Stip1 modulates the balance
Externí odkaz:
https://doaj.org/article/82875625c72b4d9c8c7eaaf0131c13bc
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26044 (2011)
Understanding the functions of proteins requires information about their protein-protein interactions (PPI). The collective effort of the scientific community generates far more data on any given protein than individual experimental approaches. The l
Externí odkaz:
https://doaj.org/article/1b6a1b1e571740f3974f8aa3f3aa49c9
Publikováno v:
Advances in cancer research. 129
The molecular chaperone Hsp90 has attracted a lot of interest in cancer research ever since cancer cells were found to be more sensitive to Hsp90 inhibition than normal cells. Why that is has remained a matter of debate and is still unclear. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43de9d1fceeab0734782ba95334c4bbb
https://pubmed.ncbi.nlm.nih.gov/26915999
https://pubmed.ncbi.nlm.nih.gov/26915999
Publikováno v:
Nucleus (1949-1034); 2010, Vol. 1 Issue 4, p299-308, 10p
Autor:
Bhattacharya, Kaushik, Weidenauer, Lorenz, Luengo, Tania Morán, Pieters, Ellis C., Echeverría, Pablo C., Bernasconi, Lilia, Wider, Diana, Sadian, Yashar, Koopman, Margreet B., Villemin, Matthieu, Bauer, Christoph, Rüdiger, Stefan G. D., Quadroni, Manfredo, Picard, Didier
Publikováno v:
Nature Communications; 11/25/2020, Vol. 11 Issue 1, pN.PAG-N.PAG, 1p
Autor:
Jennifer Isaacs, Luke Whitesell
Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of c
Autor:
Timothy D Machajewski, Zhenhai Gao
This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense int
Autor:
Walid A. Houry
Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptid