Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Pablo C, Okhuysen"'
Publikováno v:
Case Reports in Neurology, Vol 13, Iss 2, Pp 572-577 (2021)
Cerebral ischemia is a known complication of meningitis. Most Escherichia coli meningitis-induced infarcts have been reported in the neonatal and pediatric population. To the best of our knowledge, there have been no previous reports describing bilat
Externí odkaz:
https://doaj.org/article/e0b2fb0986114fc3bc0fa749e22c3db1
Autor:
Xiaotao Zhang, Gladys Browman, Wesley Siu, Karen M. Basen-Engquist, Samir M. Hanash, Kristi L. Hoffman, Pablo C. Okhuysen, Paul Scheet, Joseph F. Petrosino, Scott Kopetz, Carrie R. Daniel
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Mouse and human studies support the promise of dry beans to improve metabolic health and to lower cancer risk. In overweight/obese patients with a history of colorectal polyps or cancer, the Beans to Enrich the Gut microbiome vs.
Externí odkaz:
https://doaj.org/article/3c16c68aeee144149a7251c73c62eb8d
Autor:
Hamzah Abu-Sbeih, Lauren Nicholas Herrera, Tenglong Tang, Mehmet Altan, Anne-Maria P. Chaftari, Pablo C. Okhuysen, Robert R. Jenq, Yinghong Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background The gut microbiome impacts the efficacy of immune checkpoint inhibitor (ICI) therapy and the development of ICI-mediated diarrhea and/or colitis (IMDC). Antibiotic therapy,especially that with anaerobic activity, has profound effe
Externí odkaz:
https://doaj.org/article/c6bc8d7909414f059f27f14893546dfb
Autor:
Denise Marie A. Francisco, Liangliang Zhang, Ying Jiang, Adilene Olvera, Javier Adachi, Eduardo Yepez Guevara, Samuel L. Aitken, Kevin W. Garey, Christine B. Peterson, Kim-Anh Do, Ryan Dillon, Engels N. Obi, Robert Jenq, Pablo C. Okhuysen
Publikováno v:
Infectious Diseases and Therapy. 12:209-225
Autor:
Anubama Rajan, Matthew J Robertson, Hannah E Carter, Nina M Poole, Justin R Clark, Sabrina I Green, Zachary K Criss, Boyang Zhao, Umesh Karandikar, Yikun Xing, Mar Margalef-Català, Nikhil Jain, Reid L Wilson, Fan Bai, Joseph M Hyser, Joseph Petrosino, Noah F Shroyer, Sarah E Blutt, Cristian Coarfa, Xuezheng Song, Bv Venkataram Prasad, Manuel R Amieva, Jane Grande-Allen, Mary K Estes, Pablo C Okhuysen, Anthony W Maresso
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008851 (2020)
Enteroaggregative Escherichia coli (EAEC) is a significant cause of acute and chronic diarrhea, foodborne outbreaks, infections of the immunocompromised, and growth stunting in children in developing nations. There is no vaccine and resistance to ant
Externí odkaz:
https://doaj.org/article/15fac49c9e804f7ab44e6b10cab5b95e
Autor:
F Matthew Kuhlmann, John Martin, Tracy H Hazen, Tim J Vickers, Madeline Pashos, Pablo C Okhuysen, Oscar G Gómez-Duarte, Elizabeth Cebelinski, Dave Boxrud, Felipe Del Canto, Roberto Vidal, Firdausi Qadri, Makedonka Mitreva, David A Rasko, James M Fleckenstein
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007825 (2019)
BackgroundEnterotoxigenic Escherichia coli (ETEC) cause significant diarrheal morbidity and mortality in children of resource-limited regions, warranting development of effective vaccine strategies. Genetic diversity of the ETEC pathovar has impeded
Externí odkaz:
https://doaj.org/article/a808e145e78f402ea679a8910db41b1f
Autor:
Pablo C Okhuysen, Mayur Ramesh, Kevin W Garey, Thomas J Louie, Julian Torre Cisneros, Alena Stychneuskaya, Nino Kiknadze, Jianling LI, Esther Duperchy, Professor Mark H Wilcox, Jose G Montoya, Lori Styles, Fong Clow, Danelle James, Erik R Dubberke, Claudia M De Oliveira, Christophe Van Steenkiste
Publikováno v:
Open Forum Infectious Diseases. 9
Background Vancomycin (VAN) therapy for C. difficile infection (CDI) is effective with > 80% clinical response (CR) but is associated with 20–30% recurrence rate (rCDI). Secondary bile acids (2° BAs) inhibit C. difficile germination and help preve
Autor:
Samuel L Aitken, Joslyn Rudoni, Kayleigh R Marx, Frank P Tverdek, Samuel A Shelburne, Pablo C Okhuysen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Patients with leukemia are disproportionately vulnerable to infections caused by S. maltophilia and mortality approaches 100% in patients with hemorrhagic pneumonia. Trimethoprim-sulfamethoxazole (SXT) is the drug of choice for treatment o
Publikováno v:
Open Forum Infectious Diseases. 9
Background Bezlotoxumab is a fully human monoclonal antibody that binds and neutralizes Clostridioides difficile toxin B. Administration of bezlotoxumab along with standard of care antibiotic (SoC) treatment of C. difficile infections (CDI) is associ
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Autor:
Zaker I. Schwabkey, Diana H. Wiesnoski, Chia-Chi Chang, Wen-Bin Tsai, Dung Pham, Saira S. Ahmed, Tomo Hayase, Miriam R. Ortega Turrubiates, Rawan K. El-Himri, Christopher A. Sanchez, Eiko Hayase, Annette C. Frenk Oquendo, Takahiko Miyama, Taylor M. Halsey, Brooke E. Heckel, Alexandria N. Brown, Yimei Jin, Mathilde Raybaud, Rishika Prasad, Ivonne Flores, Lauren McDaniel, Valerie Chapa, Philip L. Lorenzi, Marc O. Warmoes, Lin Tan, Alton G. Swennes, Stephanie Fowler, Margaret Conner, Kevin McHugh, Tyler Graf, Vanessa B. Jensen, Christine B. Peterson, Kim-Anh Do, Liangliang Zhang, Yushu Shi, Yinghong Wang, Jessica R. Galloway-Pena, Pablo C. Okhuysen, Carrie R. Daniel-MacDougall, Yusuke Shono, Marina Burgos da Silva, Jonathan U. Peled, Marcel R.M. van den Brink, Nadim Ajami, Jennifer A. Wargo, Pavan Reddy, Raphael H. Valdivia, Lauren Davey, Gabriela Rondon, Samer A. Srour, Rohtesh S. Mehta, Amin M. Alousi, Elizabeth J. Shpall, Richard E. Champlin, Samuel A. Shelburne, Jeffrey J. Molldrem, Mohamed A. Jamal, Jennifer L. Karmouch, Robert R. Jenq
Publikováno v:
Sci Transl Med
Not all patients with cancer and severe neutropenia develop fever, and the fecal microbiome may play a role. In a single-center study of patients undergoing hematopoietic cell transplant ( n = 119), the fecal microbiome was characterized at onset of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f7e0812f8761b8d4fbf1944a540f64
https://europepmc.org/articles/PMC10028729/
https://europepmc.org/articles/PMC10028729/