Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Pablo A Alvarez"'
Autor:
David Balderas, Mané Ohanyan, Pablo A Alvarez, Erin Mettert, Natasha Tanner, Patricia J Kiley, Victoria Auerbuch
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010321 (2022)
The type III secretion system (T3SS) is an appendage used by many bacterial pathogens, such as pathogenic Yersinia, to subvert host defenses. However, because the T3SS is energetically costly and immunogenic, it must be tightly regulated in response
Externí odkaz:
https://doaj.org/article/31175d260d99424d9eccf832051d18ce
Autor:
Diana Hooker-Romero, Erin Mettert, Leah Schwiesow, David Balderas, Pablo A Alvarez, Anadin Kicin, Azuah L Gonzalez, Gregory V Plano, Patricia J Kiley, Victoria Auerbuch
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008001 (2019)
The enteropathogen Yersinia pseudotuberculosis and the related plague agent Y. pestis require the Ysc type III secretion system (T3SS) to subvert phagocyte defense mechanisms and cause disease. Yet type III secretion (T3S) in Yersinia induces growth
Externí odkaz:
https://doaj.org/article/2c5d6fed357a4d40ba63500af239e52f
Autor:
Marie Elise Wistrup Torm, Michael Pircher, Sophie Bonnin, Jesper Johannesen, Oliver Niels Klefter, Mathias Falck Schmidt, Jette Lautrup Frederiksen, Nicolas Lefaudeux, Jordi Andilla, Claudia Valdes, Pablo Loza-Alvarez, Luisa Sanchez Brea, Danilo Andrade De Jesus, Kate Grieve, Michel Paques, Michael Larsen, Kiyoko Gocho
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study tested if a high-resolution, multi-modal, multi-scale retinal imaging instrument can provide novel information about structural abnormalities in vivo. The study examined 11 patients with very mild to moderate non-proliferative dia
Externí odkaz:
https://doaj.org/article/676c9439b8bc439bab580766c1c33eea
Autor:
Ishier Raote, Ann-Helen Rosendahl, Hanna-Maria Häkkinen, Carina Vibe, Ismail Küçükaylak, Mugdha Sawant, Lena Keufgens, Pia Frommelt, Kai Halwas, Katrina Broadbent, Marina Cunquero, Gustavo Castro, Marie Villemeur, Julian Nüchel, Anna Bornikoel, Binita Dam, Ravindra K. Zirmire, Ravi Kiran, Carlo Carolis, Jordi Andilla, Pablo Loza-Alvarez, Verena Ruprecht, Colin Jamora, Felix Campelo, Marcus Krüger, Matthias Hammerschmidt, Beate Eckes, Ines Neundorf, Thomas Krieg, Vivek Malhotra
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies are lacking. A pro
Externí odkaz:
https://doaj.org/article/252118aa60de4fe1a96942bcae197b43
Autor:
Jesús Allende-González, José Antonio Gullón-Blanco, Eduardo Sánchez-Vázquez, Estela García-Coya, Juan Cascón-Hernández, Pablo Fernández Alvarez, Beatriz García Pulido, Lorena González Justo, Juan Rodríguez López, Gema Castaño de las Pozas
Publikováno v:
Open Respiratory Archives, Vol 6, Iss 3, Pp 100341- (2024)
Externí odkaz:
https://doaj.org/article/528276bc0b0a4647a529f8e655b44701
Autor:
Luis Pertierra, Gilda Varliero, Andrés Barbosa, Elisabeth Biersma, Peter Convey, Steven Chown, Don Cowan, Asunción De Los Rios, Pablo Escribano-Alvarez, Diego Fontaneto, Ceridwen Fraser, Mathew Harris, Kevin Hughes, Huw Griffiths, Peter le Roux, Xiaoyue Liu, Heather Lynch, Roksana Majewska, Pablo Martinez, Marco Molina-Montenegro, Miguel Olalla-Tarraga, Lloyd Peck, Antonio Quesada, Cristina Ronquillo, Yan Ropert-Coudert, Leopoldo Sancho, Aleks Terauds, Juliana Vianna, Annick Wilmotte, Joaquín Hortal, Michelle Greve
Publikováno v:
Biodiversity Data Journal, Vol 12, Iss , Pp 1-35 (2024)
Incomplete species inventories for Antarctica represent a key challenge for comprehensive ecological research and conservation in the region. Additionally, data required to understand population dynamics, rates of evolution, spatial ranges, functiona
Externí odkaz:
https://doaj.org/article/bc32e868c59f40f996ba0280d7a3189b
Publikováno v:
Medicina, Vol 60, Iss 8, p 1242 (2024)
D-waves (also called direct waves) result from the direct activation of fast-conducting, thickly myelinated corticospinal tract (CST) fibres after a single electrical stimulus. During intraoperative neurophysiological monitoring, D-waves are used to
Externí odkaz:
https://doaj.org/article/7f94f464ba5d421d98823f55c0e6ec23
Autor:
Jade Leiba, Tamara Sipka, Christina Begon-Pescia, Matteo Bernardello, Sofiane Tairi, Lionello Bossi, Anne-Alicia Gonzalez, Xavier Mialhe, Emilio J Gualda, Pablo Loza-Alvarez, Anne Blanc-Potard, Georges Lutfalla, Mai E Nguyen-Chi
Publikováno v:
eLife, Vol 13 (2024)
Numerous intracellular bacterial pathogens interfere with macrophage function, including macrophage polarization, to establish a niche and persist. However, the spatiotemporal dynamics of macrophage polarization during infection within host remain to
Externí odkaz:
https://doaj.org/article/3af0b99d3e344f90b3211f34a283ae51
Autor:
Andrea Carolina Aguilera, Natalia Leiva, Pablo Ariel Alvarez, Georgina Pulcini, Laura Lucía Pereyra, Carlos Ramón Morales, Miguel Ángel Sosa, Lorena Carvelli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The selective transport to lysosomes can be mediated by either mannose-6-phosphate receptors (CD-MPR and CI-MPR) or sortilin. In mammalian epididymis, some lysosomal proteins are secreted into the lumen through unknown mechanisms. To investi
Externí odkaz:
https://doaj.org/article/4af0af75f52e4d938fac44bf31307ead
Autor:
Miguel Lopez-Perez, Pablo Morales-Alvarez, Lee A. D. Cooper, Rafael Molina, Aggelos K. Katsaggelos
Publikováno v:
IEEE Access, Vol 11, Pp 6922-6934 (2023)
Machine learning (ML) methods often require large volumes of labeled data to achieve meaningful performance. The expertise necessary for labeling data in medical applications like pathology presents a significant challenge in developing clinical-grad
Externí odkaz:
https://doaj.org/article/78e821b163a84d5ebc1266c2dcb2f6b3