Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Pablo, Domizi"'
Autor:
Jolanda Sarno, Pablo Domizi, Yuxuan Liu, Milton Merchant, Christina Bligaard Pedersen, Dorra Jedoui, Astraea Jager, Garry P. Nolan, Giuseppe Gaipa, Sean C. Bendall, Felice-Alessio Bava, Kara L. Davis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Resistance to glucocorticoids (GC) is associated with an increased risk of relapse in B-cell progenitor acute lymphoblastic leukemia (BCP-ALL). Performing transcriptomic and single-cell proteomic studies in healthy B-cell progenitors, we her
Externí odkaz:
https://doaj.org/article/72794963275b43be963a12304dd22407
Autor:
Yu-Chen Lo, Timothy J. Keyes, Astraea Jager, Jolanda Sarno, Pablo Domizi, Ravindra Majeti, Kathleen M. Sakamoto, Norman Lacayo, Charles G. Mullighan, Jeffrey Waters, Bita Sahaf, Sean C. Bendall, Kara L. Davis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Challenges in batch normalization and data integration limit the comparison of existing mass cytometry datasets. Here, the authors report CytofIn that can integrate mass cytometry datasets from the public domain and reveal cellular features associate
Externí odkaz:
https://doaj.org/article/62feaf98a89e4b25a5f743a4912683d7
Autor:
Lu Cui, Shih-Yu Chen, Tristan Lerbs, Jin-Wook Lee, Pablo Domizi, Sydney Gordon, Yong-hun Kim, Garry Nolan, Paola Betancur, Gerlinde Wernig
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Fibroblast contributions to lung fibrosis and in particular their crosstalk with immune cells in the lung are incompletely understood. Here, the authors show an overall immune suppressive environment transcriptionally controlled and maintained by fib
Externí odkaz:
https://doaj.org/article/c31003c7ba9446ada3f7ab8183096f6b
Autor:
Johan Jeong, Astraea Jager, Pablo Domizi, Mara Pavel-Dinu, Linda Gojenola, Masayuki Iwasaki, Michael C. Wei, Feng Pan, James L. Zehnder, Matthew H. Porteus, Kara L. Davis, Michael L. Cleary
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2825-2835 (2019)
Abstract: Chromosomal rearrangements involving the mixed lineage leukemia (MLL) gene, also known as KMT2A, are often observed in human leukemias and are generally associated with a poor prognosis. To model these leukemias, we applied clustered regula
Externí odkaz:
https://doaj.org/article/0bff7eac6dd34ab39fa5dce1d7fa2b86
Autor:
Fabiana Evaristo-Mendonça, Gabriela Sardella-Silva, Tais Hanae Kasai-Brunswick, Raquel Maria Pereira Campos, Pablo Domizi, Marcelo Felippe Santiago, Ricardo Augusto de Melo Reis, Rosalia Mendez-Otero, Victor Túlio Ribeiro-Resende, Pedro Moreno Pimentel-Coelho
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Externí odkaz:
https://doaj.org/article/024e11170e7f49518ae3ad162a732fed
Autor:
Fernanda Gubert, Juliana F. Vasques, Tatiane D. Cozendey, Pablo Domizi, María Fernanda Toledo, Tais H. Kasai-Brunswick, Camila Hochman-Mendez, Mário Campos Junior, Verônica Marques Zembrzuski, Marli P.S. Loureiro, José M.B. Lima, Claudio H. Gress, Giselda M.K. Cabello, Pedro H. Cabello, Tamara Borgonovo, Isadora M. Vaz, Rosane Silva, Rosalia Mendez-Otero
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
Induced pluripotent stem cell (iPSC) line were generated from erythroblasts of a Brazilian patient with familiar form of amyotrophic lateral sclerosis (ALS). NGS analysis demonstrated that patient carried a mutation in SOD1 gene, as well as a deletio
Externí odkaz:
https://doaj.org/article/10afc6d7f50e40469bca00049c6738f4
Autor:
Fernanda Gubert, Juliana F. Vasques, Tatiane D. Cozendey, Pablo Domizi, María Fernanda Toledo, Tais H. Kasai-Brunswick, Marli P.S. Loureiro, José M.B. Lima, Claudio H. Gress, Giselda M.K. Cabello, Pedro H. Cabello, Tamara Borgonovo, Isadora M. Vaz, Rosane Silva, Rosalia Mendez-Otero
Publikováno v:
Stem Cell Research, Vol 37, Iss , Pp - (2019)
Induced pluripotent stem cell (iPSC) lines were generated from erythroblasts of two patients with amyotrophic lateral sclerosis (ALS) and two healthy individuals. One familial and one sporadic ALS patients were used, both with genetic alterations in
Externí odkaz:
https://doaj.org/article/f097656aa55746a99fd0a9b218d040ff
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210207 (2019)
The process of neuronal differentiation is associated with neurite elongation and membrane biogenesis, and phosphatidylcholine (PtdCho) is the major membrane phospholipid in mammalian cells. During neuroblast differentiation, the transcription of two
Externí odkaz:
https://doaj.org/article/539663920da947458bce02d6e62f3b45
Autor:
Fabiana Evaristo-Mendonça, Gabriela Sardella-Silva, Tais Hanae Kasai-Brunswick, Raquel Maria Pereira Campos, Pablo Domizi, Marcelo Felippe Santiago, Ricardo Augusto de Melo Reis, Rosalia Mendez-Otero, Victor Túlio Ribeiro-Resende, Pedro Moreno Pimentel-Coelho
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are dynamic cells that can sense the environment, adapting their regulatory functions to different conditions. Accordingly, the therapeutic potential of BM-MSCs can be modulated by preconditioni
Externí odkaz:
https://doaj.org/article/1c89eb8b6eb746cd84f3a8bb0e07edee
Publikováno v:
Cytometry A
The application of machine learning and artificial intelligence to high-dimensional cytometry data sets has increasingly become a staple of bioinformatic data analysis over the past decade. This is especially true in the field of cancer biology, wher